CAMBRIDGE, Mass., June 25, 2025 (GLOBE NEWSWIRE) -- Vor Bio (Nasdaq: VOR), a clinical-stage biotechnology company transforming the treatment of autoimmune diseases, today announced that it has entered into a securities purchase agreement for a private placement in public equity financing (the “PIPE”) that is expected to result in gross proceeds of approximately $175 million, before deducting expenses. Private Placement Pursuant to the terms of the securities purchase agreement, at the closing of the PIPE, V ...

周三（6月25日）纽约尾盘，现货黄金涨0.29%，报3333.42美元/盎司。 COMEX黄金期货涨0.40%，报3347.30美元/盎司。 COMEX铜期货涨1.14%，报4.9280美元/磅。 费城金银指数收涨0.08%，报203.97点。 现货白银涨0.99%，报36.2725美元/盎司。 COMEX白银期货涨1.38%，报36.225美元/盎司。 ...

Core Insights - Dakota Gold Corp. has published its 2024 Sustainability Report, aimed at enhancing understanding of its ESG strategy, practices, and risk management [1][2] - The report emphasizes transparency in communicating performance results to stakeholders, including shareholders and local communities [1] Group 1: Company Developments - The company has transitioned from exploration to development at the Richmond Hill Gold Project, marking a significant phase in its growth [3] - Dakota Gold has achieved four years without a lost time incident and zero reportable environmental incidents since drilling began in early 2022, highlighting its commitment to health and safety [3] Group 2: Project Focus - Dakota Gold is advancing the Richmond Hill Oxide Heap Leach Gold Project towards commercial production and is outlining a high-grade underground gold resource at the Maitland Gold Project [5]

Group 1 - The 2025 Annual and Extraordinary General Meeting of Alvotech was held on June 25, 2025, in Luxembourg [1] - All draft resolutions on the agenda of the 2025 AGM were approved [1] - Notarized meeting minutes and voting results will be published on the Company's special web portal [1]

Core Insights - Vor Bio has secured exclusive global rights (excluding Greater China) to develop and commercialize telitacicept, a dual-target recombinant fusion protein for autoimmune diseases [1][6] - RemeGen has received an initial payment of $125 million, which includes a $45 million upfront payment and $80 million in warrants, along with potential milestones exceeding $4 billion and tiered royalties [1][5] - Jean-Paul Kress, MD, has been appointed as the new CEO and Chairman of Vor Bio, bringing extensive experience in clinical development and commercialization [3][4] Company Developments - Vor Bio is focused on advancing telitacicept through Phase 3 clinical development to address serious autoantibody-driven conditions globally [7] - RemeGen is conducting a global Phase 3 clinical trial for telitacicept, with initial results expected in the first half of 2027 [2][6] - The strategic out-licensing of telitacicept's ex-China rights is aimed at maximizing its clinical and commercial potential on a global scale [5] Product Information - Telitacicept targets key immune pathways by inhibiting BlyS (BAFF) and APRIL, which are critical for B cell survival, thereby reducing autoreactive B cells and autoantibody production [2][5] - In a Phase 3 trial in China for generalized myasthenia gravis, telitacicept showed a 4.8-point improvement in the MG-ADL scale compared to placebo at 24 weeks [5]

Core Insights - Kodiak Sciences Inc. is presenting KSI-101, a bispecific investigational biologic targeting macular edema secondary to inflammation, at the 2025 Congress of the International Ocular Inflammation Society in Rio de Janeiro [1][6] - The company aims to address the significant unmet need in treating macular edema caused by inflammation, which can lead to vision loss [3][4] Company Overview - Kodiak Sciences is a precommercial biotechnology company focused on developing therapeutics for retinal diseases, utilizing its ABC Platform for innovative drug design [8][9] - The company is advancing its pipeline, which includes three late-phase clinical assets expected to deliver Phase 3 topline data in 2026 [9] Product Details - KSI-101 is a high-strength (100 mg/mL) bispecific protein designed to target both interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF), addressing the dual mechanisms of macular edema [6][5] - The ongoing Phase 1b study, APEX, is evaluating the safety and tolerability of KSI-101, with plans to progress into dual Phase 2b/3 studies [7]

Company Overview - Proactive is a financial news publisher that provides fast, accessible, informative, and actionable business and finance news content to a global investment audience [2] - The company has a team of experienced news journalists who produce independent content across various financial markets [2] Market Focus - Proactive specializes in medium and small-cap markets while also covering blue-chip companies, commodities, and broader investment stories [3] - The content includes insights into sectors such as biotech and pharma, mining and natural resources, battery metals, oil and gas, crypto, and emerging digital and EV technologies [3] Technology Adoption - Proactive is committed to adopting technology to enhance its content creation and workflow processes [4] - The company utilizes automation and software tools, including generative AI, while ensuring that all published content is edited and authored by humans [5]

发展多层次农业保险、完善农业保险大灾风险分散机制、推进农业保险精准投保理赔……近年来，监管 部门出台一系列政策，推动农业保险发展。在广袤的乡村大地上，保险业正发挥着越来越重要的作用。 中国证券报记者了解到，保险业通过持续创新产品、优化服务模式、深化科技赋能等措施，引金融服务 入田间地头，提升农业经营主体的抗风险能力，助力乡村全面振兴。 丰富农业保险产品体系 近年来，农业保险作为关键的风险管理工具，覆盖面与保障水平显著提升。从三大主粮作物完全成本保 险和种植收入保险，到地方特色农产品保险，农业保险产品体系日益丰富。 财政部披露的数据显示，全面实施三大粮食作物完全成本保险和种植收入保险政策，有序扩大大豆完全 成本保险和种植收入保险政策范围。全年拨付中央财政农业保险保费补贴547亿元，支持我国农业保险 保费规模1521亿元，为1.47亿户次农户提供风险保障超5万亿元。 水稻、小麦、玉米三大主粮作物承载着我国人口的口粮需求。国寿财险相关负责人表示，2024年，公司 围绕三大主粮作物的保险保障，主动作为，承保三大主粮作物种植面积超1.15亿亩，其中承保完全成本 保险约8688万亩，提供风险保障约805亿元。此外，202 ...

Core Insights - A new study indicates that Uber successfully raised fares, reduced driver pay, and increased profits through a pricing strategy known as "upfront pricing" [1][4][21] Group 1: Pricing Strategy - In 2022, Uber transitioned to "upfront pricing," which provides riders with a price and drivers with potential earnings before trip acceptance [2][3] - This pricing model utilizes various factors beyond trip length and demand to set prices, allowing for more precise pricing strategies [2][3] - The implementation of upfront pricing has been linked to a significant stock price increase of nearly 300% over three years [3][6] Group 2: Financial Impact - The study found that upfront pricing enabled Uber to systematically raise rider fares while cutting driver pay across billions of rides [4][21] - The take rate, or the percentage of fare that Uber retains, increased from approximately 32% in 2022 to about 42% by the end of 2024, with some trips seeing Uber take over 50% [19][21] - The financial performance of Uber improved significantly, culminating in the company reporting its first annual profit in 2023 [6] Group 3: Driver Experience - The analysis, based on data from a single driver, revealed that driver earnings have decreased since the introduction of upfront pricing, despite rising operational costs [8][10] - The driver in the study experienced pay cuts starting in September 2022, coinciding with the rollout of the new pricing model [10] - Many drivers have reported a significant drop in their share of fares, with one driver noting a decrease from over 50% to less than 30% of the total fare [12][13] Group 4: Economic Theory - The study suggests that Uber has mastered "price discrimination," allowing it to determine the maximum price riders are willing to pay and the minimum drivers will accept [5][6] - This concept, previously theoretical, has been operationalized by Uber through its data and algorithms, positioning the company as a leader in this pricing strategy [6]

Atlantic Lottery to leverage IGT's next-generation, cloud-based IntelligenEVO technology to enhance system performance and player experienceLONDON, June 25, 2025 /PRNewswire/ -- International Game Technology PLC (NYSE: IGT) announced today that its subsidiary, IGT Canada Solutions ULC (hereinafter "IGT"), signed an eight-year agreement with Atlantic Lottery to supply its IntelligenEVO™ video lottery central system technology across Atlantic Canada. The agreement includes the option for multiple extensions a ...