Core Insights - NANO Nuclear Energy Inc. congratulates its partner LIS Technologies for receiving a Radioactive Material License from the State of Tennessee, allowing LIS to procure uranium hexafluoride (UF₆) feedstock and advance its patented laser uranium enrichment technology [1][2][4] Group 1: Company Developments - LIS Technologies is the only U.S.-origin developer of patented advanced laser technology for uranium enrichment, enabling it to handle various forms of uranium and support technology development for a commercial uranium laser enrichment facility [2][3] - NANO Nuclear and LIS Technologies have a collaboration agreement where NANO Nuclear will develop fuel cycle capabilities to integrate LIST's enriched UF₆ into a manufacturing process, supporting both NANO Nuclear's micro modular reactors and the broader nuclear energy industry [3][4] Group 2: Strategic Importance - The achievement of the Radioactive Material License is seen as a major milestone for the U.S. nuclear fuel supply chain, with NANO Nuclear emphasizing the importance of restoring domestic enrichment capacity for advanced reactors [4] - NANO Nuclear believes that LIST's laser enrichment technology could eventually produce commercial quantities of Low Enriched Uranium (LEU) and High-Assay Low Enriched Uranium (HALEU) fuel, contributing to U.S. domestic enrichment capabilities [4] Group 3: Financial and Regulatory Context - In late 2024, LIST was selected by the U.S. Department of Energy for a $3.4 billion contract aimed at expanding U.S. domestic commercial enrichment capabilities, with NANO Nuclear acting as a key subcontractor [4]

Core Viewpoint - NANO Nuclear Energy Inc. celebrates its commercial partner LIS Technologies Inc. receiving a Radioactive Material License from the State of Tennessee, marking a significant milestone for the U.S. nuclear fuel supply chain and the development of advanced nuclear technologies [1][6]. Group 1: License and Technology Development - The Radioactive Material License allows LIST to procure uranium hexafluoride (UF₆) feedstock and advance research and development for a commercial uranium laser enrichment facility in the U.S. [2] - LIST is recognized as the only U.S.-origin developer of patented advanced laser technology for uranium enrichment, which is crucial for NANO Nuclear's fuel cycle capabilities [3]. Group 2: Collaboration and Strategic Importance - NANO Nuclear and LIST have a collaboration agreement where NANO Nuclear will develop fuel cycle capabilities to integrate LIST's enriched UF₆ into a manufacturing process, supporting both NANO Nuclear's micro modular reactors and the broader nuclear energy market [3]. - The partnership aims to restore secure domestic enrichment capacity and support the next generation of advanced reactors, reinforcing a vertically integrated U.S. nuclear fuel platform [6]. Group 3: Government Support and Future Prospects - In late 2024, LIST was awarded a contract by the U.S. Department of Energy as part of a $3.4 billion initiative to enhance U.S. domestic enrichment capabilities, with NANO Nuclear serving as a key subcontractor [6]. - NANO Nuclear believes that LIST's laser enrichment technology has the potential to produce commercial quantities of Low Enriched Uranium (LEU) and High-Assay Low Enriched Uranium (HALEU) fuel in the future [6].

Registration No. 333-[_______] UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 As filed with the U.S. Securities and Exchange Commission on October 21, 2024. FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 NANO NUCLEAR ENERGY INC. (Exact Name of Registrant as Specified in its Charter) (Primary Standard Industrial Classification Code Number) Nevada 4911 88-0861977 (I.R.S. Employer Identification No.) 10 Times Square, 30Floor New York, New York 10018 (212) 634-9206 (Ad ...