Core Viewpoint - The controversy surrounding the collagen content in the product "Human-Like Recombinant Collagen" from the brand Kefu Mei, owned by the company Giant Bio, has raised significant concerns regarding product integrity and testing methods [1][2][3]. Group 1: Controversy Details - KOL "Dr. Big Mouth" (Hao Yu) claimed that tests showed the collagen content in Kefu Mei's product was only 0.0177% using HPLC amino acid quantification [1]. - Giant Bio responded by stating their tests indicated collagen content greater than 0.1%, contradicting the claims made by Hao Yu, but third-party test results are still pending [2]. - Hao Yu further questioned Giant Bio's testing methods, suggesting that the use of the biuret method could lead to inflated results due to the presence of sodium polyglutamate in the product [3]. Group 2: Previous Issues and Impact - This is not the first controversy for Kefu Mei in 2023, as the brand was previously accused of illegally adding epidermal growth factor (EGF), which led to a public trust crisis [4][5]. - The Shaanxi Provincial Drug Administration investigated the previous claims and found no violations after sampling [6]. - The outcome of the current controversy is crucial for Giant Bio's future performance, as Kefu Mei is projected to generate revenue of 4.542 billion yuan in 2024, contributing over 80% to the company's total revenue [6]. Group 3: Market Reaction - Despite the unresolved testing results, the controversy has significantly impacted Giant Bio's stock price [7]. - As of May 29, Giant Bio's market capitalization was 72.9 billion HKD, having lost 12.8 billion HKD since early May [8].

作 者丨凌晨 编 辑丨骆一帆 最新的进展是，该博主在5月27日晚，公开了一份自称为"巨子生物向各大平台的举报材料"。 近日，一条"巨子生物疑似造假：重组胶原竟然测不到胶原！"的视频及图文网帖，引爆讨 论。 其中，检测方法对于成分含量影响的争议，双方各执一词。 可复美送检方法被公开？ 21世纪经济报道记者查阅多篇知网文献发现，双缩脲法在蛋白质检测中仍有争议。 2008年《河北化工》刊文《蛋白质含量测定方法的比较》中提到，双缩脲法中样品的取用量 对测定结果的准确性有显著影响。双缩脲法可快速测定蛋白质含量，试剂单一，方法简便， 但灵敏度差，测定范围为 1～20 mg 蛋白质。适用于需要快速,但并不需要十分精确的蛋白质 测定。 2019年，来自广东医科大学药学院、广东省医疗器械质量监督检验所的六位行业人士撰文中 提到："缩脲法测定Ⅰ型胶原蛋白含量，测定方法经济，简便，测定结果准确，重现性 好。"其中，Ⅰ型胶原蛋白是皮肤的主要成分，广泛应用于皮肤修复和化妆品行业。 据显示，上述材料名为"关于申请协调删除恶意诋毁诽谤内容的函"。 其中提到巨子生物采用《中华人民共和国药典》2020版四部通则0731第三法及中华人民共和 国 ...

Core Viewpoint - The controversy surrounding the authenticity of collagen content in a product by Juzhi Biotechnology has sparked significant discussion, particularly regarding the testing methods used to measure collagen levels [1][2]. Group 1: Testing Methods and Controversy - The testing method used by Juzhi Biotechnology, known as the Biuret method, has been questioned for its reliability in complex cosmetic formulations, as it may yield inflated results due to interference from other ingredients [5][7]. - A blogger has raised concerns that the Biuret method cannot accurately distinguish between collagen and other peptide components, such as sodium polyglutamate, which could lead to misleading results [5][6]. - The blogger also highlighted discrepancies between the product versions sent for testing by Juzhi Biotechnology and their own submissions, indicating potential inconsistencies in the testing process [6]. Group 2: Regulatory Attention and Market Impact - The controversy has attracted regulatory scrutiny, with local market supervision authorities acknowledging the issue and beginning investigations [9][10]. - Following the controversy, the 1.0 version of the product has reportedly been removed from major e-commerce platforms, while the 2.0 version remains available for sale [10].

Group 1 - The annual 618 shopping festival is a significant opportunity for both consumers and businesses to drive growth in a competitive market [2] - JD.com has upgraded its "Navigation Plan" during the 618 period, offering substantial incentives and new marketing strategies to help merchants enhance their promotional performance [2][5] - The BRIDGE smart product effectiveness solution has been introduced by JD.com to address the challenges faced by brands in the evolving marketing landscape [5][8] Group 2 - BRIDGE is built on the ACME marketing methodology, focusing on essential capabilities for brand growth, and provides a comprehensive framework for brands to achieve sustainable growth [5][7] - The BRIDGE solution consists of six components: Business Insights, Relationship, Integrated Content Marketing, Dynamic Traffic Aggregation, Goods Operations, and Effect, addressing various brand operational challenges [7][10] - The solution emphasizes practical application and is designed to be directly executable, enhancing brands' ability to navigate complex market dynamics [8][10] Group 3 - JD.com has launched three major upgrades in its smart services, focusing on product capability enhancement, data openness, and intelligent marketing strategies to support brand growth [15][17] - The content marketing upgrade aims to strengthen partnerships with social media platforms, creating a seamless link between content seeding and conversion on JD.com [17][20] - The intelligent marketing cloud and data integration initiatives are designed to break down data silos, enabling brands to gain deeper insights into consumer behavior and optimize their marketing strategies [20][22] Group 4 - The BRIDGE solution facilitates targeted strategies for various marketing scenarios, including new customer acquisition, existing customer re-engagement, and new product launches [9][11] - For instance, OPPO utilized the BRIDGE framework to enhance its marketing efficiency during the launch of the Find X8 series, ensuring precise targeting of potential customers [11][13] - The integration of market trends and consumer insights into product development processes is exemplified by successful collaborations, such as with Nestlé and Starbucks, leading to significant sales achievements [13][14]

交易量柱通常代表在与图表所设定时间框架相同的时间段内买入和卖出的单位总数。例如，在日线图中，每一根交易量柱表示当天的市场总交易量；在小 时图中，每根交易量柱表示该小时内的交易量。 不过，在外汇品种中，交易量的计算方式可能略有不同，具体取决于经纪商。 当市场中价格波动时，通常是因为它乘着更高交易量的浪潮前进。有时，这些浪潮是推动价格进入趋势的大潮的一部分；而另一些时候，在交易量的"海 洋"中出现的漩涡会导致价格出现一定程度的无序波动。或者，市场可能风平浪静、交易量低迷，从而形成窄幅震荡区间。 无论市场水面状态如何，价格最终总是"浮"在交易量之上。 许多技术分析者只关注价格行为本身，而忽略了交易量——至少在我浏览各种交易论坛或社交群组时经常看到这种情况，而我自己也承认曾犯过同样的错 误。然而，将价格行为与交易量结合起来观察，可以揭示出一层全新的、可操作的信息。 让我们来看一下交易量在技术分析中的作用，以及如何将这一知识应用于实际交易中。 什么是外汇市场中的"交易量"？ 交易量如何计算？ 外汇市场是场外交易（OTC）市场，也就是说，没有统一的中央交易所。外汇经纪商的图表上只显示他们自身的交易量信息，而不是整个行业的 ...

Core Viewpoint - The controversy surrounding the alleged fraud of the collagen essence product from Giant Biological (02367.HK) continues to escalate, with significant focus on the testing methods used to validate the claims made by Dr. Hao Yu, who has accused the product of containing only 0.0177% of recombinant collagen [1][3][5]. Group 1: Allegations and Responses - Dr. Hao Yu claims that the key component "glycine" is missing from the collagen essence, raising doubts about the product's authenticity [3]. - Giant Biological has issued a statement denying the allegations, asserting that their internal testing shows collagen content greater than 0.1%, contradicting Dr. Hao's findings [5][6]. - The company emphasizes adherence to regulatory standards and claims that all products undergo rigorous quality control processes [6][8]. Group 2: Testing Methods - The testing methods used by Dr. Hao Yu have been questioned by Giant Biological, which argues that the methods are not recognized by industry standards and lack proper validation [1][10]. - Dr. Hao Yu defends his use of high-precision HPLC amino acid quantification method, stating it is widely accepted internationally and has been validated for accuracy [1][10]. - Giant Biological has committed to obtaining third-party testing results to further validate their claims, indicating that they are awaiting the results from multiple authoritative testing agencies [2][8]. Group 3: Industry Context - The lack of established industry standards for measuring recombinant collagen content in cosmetics has been highlighted as a significant issue in this controversy [10]. - Dr. Hao Yu's background in organic chemistry and experience in the cosmetics industry lend credibility to his claims, although he asserts that there is no competitive motive behind his allegations [11][14]. - The ongoing debate raises questions about product quality and consumer trust in the cosmetic industry, particularly regarding the accuracy of ingredient labeling [16].

Core Points - The 9th China Brand Boao Summit was successfully held in Hainan on May 24, 2025, focusing on the theme "Building Brand Development Together" [1] - The summit aimed to promote strong Chinese brands and featured notable companies such as DJI, Meituan, Xiaomi, and Huawei [1] - The "Leading Brand in Strategic Consulting" award was introduced to encourage the development of high-level professional brand consulting firms in China [1][9] Group 1 - The "Leading Brand in Strategic Consulting" award received significant attention from over 50 well-known strategic consulting companies across major cities like Shanghai, Beijing, and Shenzhen [1] - Victory Bird Brand Strategy Consulting was recognized as a representative of a new generation of strategic consulting firms, winning the award for its "Scientific Strategy" methodology [1][3] - Experts acknowledged the "Scientific Strategy" proposed by Victory Bird, emphasizing the importance of scientifically-based strategic customization for business development [3] Group 2 - The "Strategic Triangle" tool introduced by Victory Bird effectively combines strategy with preparation, campaigns, and tactics, creating a strategic loop [3] - The founder of Victory Bird, Zhu Hongwen, highlighted the need for a unique methodology in China's strategic consulting industry, which is still in its early stages [4] - Victory Bird's rapid growth is notable, having secured a strategic consulting contract with the state-owned listed company Yantang Dairy on April 12, 2025, based on its innovative methodology and excellent practical results [5][6] Group 3 - Zhu Hongwen became the first recipient of the "Chinese Brand Observer" title, showcasing Victory Bird's professional standards in the field [9] - The emphasis on behavioral and neuroscience in developing strategic methods tailored for Chinese enterprises is a significant aspect of Victory Bird's approach [9] - The emergence of numerous strategic consulting firms in China over the past decade indicates a rising trend in the industry [9]

研究人员进一步发现，未被回收的PET饮料包装大多流入了厨余垃圾处理厂、垃圾填埋场、垃圾焚烧 厂，甚至有部分散落在海滩等自然环境中，其中垃圾焚烧厂是流失的PET饮料包装最大"出口"。通过逆 向核算，扣除这些流失的部分，其回收率在96.86%—97.63%之间。综合正、逆向"双线"核算，我国PET 饮料包装回收率已高达96.48%—97.63%，相当于每年超过430万吨的饮料瓶实现了正规渠道回收利用。 多方合力推动提升回收率 "在废弃塑料中，PET塑料瓶是回收率最高的产品，再生PET瓶片也是最成熟的再生塑料产品。"宁夏银 川某环境科技有限公司总经理李双平告诉记者，"回收后的瓶子，需要进行拆包、分类、滚筛、脱标、 色选、破碎、清洗等工序，破碎后的塑料瓶薄片将浸泡在工业洗涤槽中，然后通过沉浮分离箱内的桨轮 系统进行混合，像瓶盖、标签纸这样低密度的塑料会漂浮在水面上，其他塑料则会沉积到底部。" 据了解，再生PET材料可广泛应用于服装面料领域，这是目前应用最多的领域。再生PET粒料经"瓶到 瓶"回收工艺可用于生产食品级包装容器。此外，PET瓶回收料可以制备非结晶PET片材、包装用带材、 波纹形遮阳蓬等。再生PET经玻璃纤 ...

Core Viewpoint - The ongoing dispute regarding the detection methods for recombinant collagen in cosmetics has raised significant concerns about the reliability of testing methods used by the company, Juzhi Biotechnology, and the implications for consumer trust [1][4]. Group 1: Detection Methods - Juzhi Biotechnology referenced the "Detection Methods for Recombinant Collagen Content" from the Chinese medical industry standard YY/T 1947-2025, which includes two main types of detection methods [1][2]. - The first method is the "mass spectrometry method," which is primarily used for tissue regeneration materials and is not suitable for complex cosmetic formulations due to potential interference from other ingredients [2][3]. - The second method includes six techniques, with the Kjeldahl method being the most likely choice for Juzhi Biotechnology, despite its limitations in accurately assessing specific proteins in complex formulations [2][3]. Group 2: Product Withdrawal and Consumer Trust - Juzhi Biotechnology's product, Human-Like Recombinant Collagen Essence, has been removed from major sales channels, raising questions about the company's testing results [4]. - The claim that testing for recombinant collagen content requires raw materials from Juzhi is misleading, as the product itself can be purchased for independent testing [4][5]. - The company's practice of not selling raw materials externally may pose risks, as it limits independent verification and peer review of their recombinant collagen [4][5]. Group 3: Questions and Concerns - There are significant concerns regarding the independence of any future sample testing if Juzhi Biotechnology provides the samples themselves, as this could lead to questions about the integrity of the results [5]. - Two critical questions remain unanswered by Juzhi Biotechnology: the absence of the core amino acid glycine in the tests and the potential misrepresentation of dipeptides as "mini collagen" [5].

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