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Plus Therapeutics Announces FDA Clearance of its Investigational New Drug Application using REYOBIQTM for the Treatment of Childhood Brain Cancer
GlobeNewswire News Room· 2025-06-25 11:30
Core Insights - Plus Therapeutics has received FDA clearance for its Investigational New Drug application for REYOBIQ, aimed at treating pediatric patients with high-grade glioma and ependymoma [2][5] - The Phase 1/2a trial, named ReSPECT-PBC, is supported by a $3 million grant from the U.S. Department of Defense and will focus on determining the maximum tolerated dose and safety of REYOBIQ in children aged 6 to 21 [1][4][7] Company Overview - Plus Therapeutics is a clinical-stage pharmaceutical company based in Houston, Texas, specializing in targeted radiotherapeutics for central nervous system cancers [9] - The company is advancing a pipeline that includes treatments for recurrent glioblastoma, leptomeningeal metastases, and pediatric brain cancer [9] Trial Design and Objectives - The ReSPECT-PBC trial is a two-part, single-arm study designed to assess the safety and tolerability of REYOBIQ, with a focus on pediatric patients with rare and aggressive brain tumors [4][7] - The trial will enroll approximately 56 patients, with 24 in Phase 1a for dose escalation and 32 in Phase 2a to assess efficacy [7] Treatment Potential - REYOBIQ is designed to deliver high doses of beta radiation directly to brain tumors while minimizing damage to surrounding healthy tissue, potentially improving outcomes for patients with limited treatment options [5][8] - The targeted delivery method via convection enhanced delivery (CED) aims to bypass the blood-brain barrier, which is a significant challenge in treating CNS tumors [4][5]
Seres Therapeutics(MCRB) - 2025 Q1 - Earnings Call Presentation
2025-06-25 11:20
Seres Therapeutics Investor Presentation May 2025 Disclaimers 2 Seres Therapeutics, Inc. © 2025 2 Transforming patient outcomes using proprietary consortia of live biotherapeutics Strong Foundation Forward Looking Statements This communication contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this communication that do not relate to matters of historical fact should be considered forward-looking statements, including s ...
Amkor Technology (AMKR) Earnings Call Presentation
2025-06-25 09:03
Enabling the Future Amkor Technology Investor Presentation May 2025 © 2025 Amkor Technology, Inc. 1 Disclaimer Non-GAAP Measures This presentation contains certain measures that are not defined terms under U.S. generally accepted accounting principles ("GAAP"). These non-GAAP measures should not be considered in isolation or as a substitute for, or superior to, measures of liquidity or performance prepared in accordance with U.S. GAAP and may not be comparable to calculations of similarly titled measures by ...
Phathom Pharmaceuticals: Potential Blockbuster Gastric Acid-Reducing Drug With New Mechanism
Seeking Alpha· 2025-06-25 08:54
With a robust academic background including an MBA in Finance from NYU-Stern, and an MD from Delhi University, my journey in the financial world has been diverse and enriching. My postgraduate training in medicine was conducted at Harvard and Cornell affiliated hospitals, thus laying a solid foundation for my current expertise. As a registered investment advisor and professional money manager, I bring nearly a decade of experience in writing about income investing and biotech/pharma investing. My role at Va ...
WISeSat Signs a Service Agreement with Astrocast to Allow Access to Astrocast's Operational Satellite Constellation
GlobeNewswire News Room· 2025-06-25 05:00
FOR IMMEDIATE RELEASE WISeSat Signs a Service Agreement with Astrocast to Allow Access to Astrocast’s Operational Satellite Constellation Geneva, Switzerland – June 25, 2025 – WISeKey International Holding Ltd (“WISeKey”) (SIX: WIHN, NASDAQ: WKEY), a leading global cybersecurity, blockchain, and IoT company, today announces that its subsidiary, WISeSat.Space, a provider of secure satellite communications and space infrastructure, signed a strategic collaboration agreement with Astrocast, a Swiss-based nanos ...
WISeSat Signs a Service Agreement with Astrocast to Allow Access to Astrocast’s Operational Satellite Constellation
Globenewswire· 2025-06-25 05:00
FOR IMMEDIATE RELEASE WISeSat Signs a Service Agreement with Astrocast to Allow Access to Astrocast’s Operational Satellite Constellation Geneva, Switzerland – June 25, 2025 – WISeKey International Holding Ltd (“WISeKey”) (SIX: WIHN, NASDAQ: WKEY), a leading global cybersecurity, blockchain, and IoT company, today announces that its subsidiary, WISeSat.Space, a provider of secure satellite communications and space infrastructure, signed a strategic collaboration agreement with Astrocast, a Swiss-based nanos ...
Verizon Business wins multisite private 5G contract fueling a multibillion dollar regeneration project
Globenewswire· 2025-06-25 04:01
Core Insights - Verizon Business, Thames Freeport, and Nokia have formed a strategic partnership to implement Verizon Private 5G Networks in key logistics, manufacturing, and innovation sites along the River Thames Estuary in the UK, aiming for a multiyear, multibillion-dollar operational transformation and economic revival in the region [2][4]. Group 1: Economic Impact - The deployment of Private 5G Networks is expected to create a scalable connectivity foundation for advanced data, AI, edge computing, and IoT infrastructure, enhancing port and manufacturing operations [3][10]. - Thames Freeport has already generated 1,400 jobs and aims to reach 5,000 by 2030, focusing on high-skilled training for local communities [4][10]. Group 2: Technological Advancements - The Private 5G Networks will enable capabilities such as AI-driven data analytics, predictive maintenance, process automation, autonomous vehicle control, safety monitoring, and real-time logistics orchestration [5][9]. - Nokia will provide the hardware and software for the networks, incorporating the Nokia Digital Automation Cloud (DAC) platform and Nokia MX Industrial Edge (MXIE) [5][9]. Group 3: Strategic Goals - The Thames Freeport initiative aims to stimulate trade, foster innovation, support energy transition, create jobs, and improve local living conditions [10][11]. - The use of IoT for autonomous operations and AI for environmental monitoring will enhance operational efficiency and sustainability at the Freeport [11][12].
Nokia selected by Verizon as hardware and software provider for Thames Freeport multisite private 5G deal
Globenewswire· 2025-06-25 04:00
Core Insights - Nokia has been selected by Verizon as the hardware and software provider for the deployment of Private 5G Networks at Thames Freeport, which is expected to drive a multi-year, multi-billion dollar operational transformation in the region [1][5][10] Group 1: Partnership and Economic Impact - The partnership aims to enhance logistics, manufacturing, and innovation across key sites along the River Thames Estuary, contributing to economic revival and job creation [1][3] - Thames Freeport has already created 1,400 jobs and aims to reach 5,000 by 2030, focusing on high-skilled training for local communities [3][10] Group 2: Technological Advancements - The Verizon Private 5G Networks will enable advanced capabilities such as AI-driven data analytics, predictive maintenance, process automation, and real-time logistics orchestration [4][9][11] - The deployment will incorporate Nokia's Digital Automation Cloud (DAC) platform and MX Industrial Edge (MXIE), facilitating a scalable connectivity foundation for IoT and edge computing [4][9] Group 3: Strategic Goals and Future Vision - The initiative is part of a broader mission for economic regeneration, operational excellence, and innovation leadership, aiming to stimulate trade and attract global investment [6][10] - The deployment is positioned as one of the largest commercial private 5G rollouts in a European port, showcasing the potential of private wireless networks for industrial transformation [9][10]
首个芯片设计企业业绩预告出炉,泰凌微(688591.SH)上半年归母净利已超24年全年
Xin Lang Cai Jing· 2025-06-25 03:15
二季度已临近尾声,A股上市公司已经陆续开始披露半年度业绩预告。Choice金融终端数据显示,截至 6月24日晚间,A股共有21家上市公司对外披露了2025年半年度的业绩预告,范围涵盖多家行业龙头公 司。 科创板层面,至撰稿时已有影石创新、甬矽电子、圣诺生物、广大特材、泰凌微、达梦数据、京仪装 备、青达环保8家企业披露了业绩预告。值得注意的是,泰凌微是今年首家披露业绩预告的芯片设计企 业。 一季度高增长水平得以延续 上半年利润已超去年全年 今年3月下旬,泰凌微凭借"历史最好一季度表现"和一系列超预期的基本面数据表现引发市场追捧,从 此次半年度预告中可见,今年一季度的优异表现和高增速在二季度得到了延续,业绩处于成长期的逻辑 进一步巩固。 具体来看,预计2025年半年度实现营业收入5.03亿元左右,同比增加37%左右;归母净利润9900万元左 右,增幅267%左右;归母扣非净利润9500万元左右,增幅265%左右,若剔除本期计提的约2200万的股 份支付费用以及相关所得税的影响,则净利润可以来到约1.19亿元的规模。 无论是否剔除该部分的影响,上半年扣非前后归母净利润均已经超过了2024年全年的水平。 报告期里,各 ...
チャリティじゃなく、チャンスを | Tatsuo Yamashita | TEDxAPU
TEDx Talks· 2025-06-24 16:50
「障がいが重すぎるから、養護学校にも入れない」そんな理不尽な現実に立たされた少年が、出会いと挑戦を通じて理事長となり、今では1,000人を超える障がいのある人たちの雇用を支える存在に。 人生を変えたのは、人との出会い。そして、自らもその“出会い”になろうと歩み続けた道のり。このトークでは、障がい、挫折、葛藤を超えてきた山下さんが、「No Charity, but a Chance(保護ではなく、機会を)」という太陽の家の理念のもと、希望と行動の大切さを語ります。 できない理由ではなく、“できる方法”を探す。誰もが社会の一員として輝ける未来へ。それは、あなたの出会いから始まるかもしれません。 At the age of one, he developed polio due to persistent high fever, and became wheelchair-bound. In 1984, he joined Mitsubishi Corporation Taiyo Co., Ltd., an IT company, and became its president and CEO in 2014 a ...