为验证其有效性，团队让AI设计激活荧光蛋白基因的DNA序列，并将其插入小鼠血细胞基因组的随机 位置。结果显示，基因表达完全符合预期，证明AI设计的合成增强子功能正常。 科技日报讯 （记者张梦然）《细胞》杂志5月8日发表了一项新研究：西班牙基因组调控中心团队利用 生成式人工智能（AI），设计出一种合成DNA序列，可作为"基因开关"，控制哺乳动物特定细胞中的 基因表达。这一进展堪称合成生物学领域的一个里程碑。 这项技术可根据特定需求，从零开始"创作"自然界中不存在的DNA片段。团队训练AI模型预测合适的 DNA字母组合（A、T、C、G），以实现特定细胞类型中的基因表达模式。例如，可以让干细胞开启某 个基因，从而发育成红细胞而不是血小板。随后，研究人员将这些约250个字母长度的DNA片段合成出 来，并通过病毒载体导入细胞中。 不过，要训练这样的AI模型并不容易，与增强子相关的高质量数据一直匮乏。为此，团队在过去5年中 开展了超过64000次实验，构建了迄今为止最大的血细胞合成增强子数据库。他们测试了38种不同转录 因子的结合位点排列和强度，并追踪每种增强子在血细胞发育7个阶段中的活性变化。 研究还发现了一些有趣的现 ...

Group 1 - Healthy eating is no longer an optional lifestyle choice but a fundamental aspect of pursuing a high-quality life and maintaining physical and mental health [1] - A balanced, moderate, and diverse diet is essential for health, ensuring the intake of proteins, carbohydrates, healthy fats, vitamins, and minerals [1][3] - Overconsumption of any nutrient can lead to health issues such as obesity, cardiovascular diseases, and diabetes, emphasizing the importance of moderation in dietary choices [3] Group 2 - A diverse diet not only ensures comprehensive nutrient intake but also enhances the enjoyment of food, preventing monotony and overeating [3] - The internet provides vast resources for healthy eating, allowing access to nutritional knowledge, dietary plans, and diverse culinary cultures [3] - The application of internet technologies like big data and artificial intelligence is driving the trend towards more precise and personalized healthy eating solutions [5] Group 3 - The industry is witnessing a transformation as companies leverage the internet for marketing and sales, utilizing platforms like mini-programs and social media for targeted outreach [5]

作为欧洲家用电梯行业的创新引领者,SWIFT 斯伟特近年来在全球家用电梯市场表现瞩目。近日,品牌联 合创始人兼首席执行官 Tommy Lowback 接受专访,深度解析 SWIFT 斯伟特背后的技术创新、全球化战 略布局,以及他对家用电梯行业未来发展的独到见解。 技术驱动革新:重新定义家用电梯的家庭适配性 采访中,Tommy Lowback 重点介绍了 SWIFT斯伟特的核心技术优势。品牌诞生于瑞典,沿袭了北欧在精 密工程和人性化设计方面的传统,所研发的 SWIFT斯伟特 家用电梯采用先进的螺母螺杆驱动系统,并融合 自主研发的 SWIFT Eco-Drive 生态驱动技术,为家庭用户带来更加平稳、安静且节能的乘梯体验。实 现"平均每四次运行中有一次免费"。即便在断电情况下,电梯仍可支持 10 至 20 次全速运行,有效解决传 统电梯依赖市电的痛点。 "我们希望家用电梯真正服务于家庭,而不仅仅是单一的楼层通行工具。" Tommy 表示。SWIFT Pro 还搭 载了 Dynamic Display 智能触摸屏,智能触摸屏可通过场景模式适配不同家庭成员需求,从老年用户青睐 的极简控制面板到年轻群体的个性化灯光设置 ...

Core Insights - The future development trends of automatic bagging machines will focus on intelligence, environmental sustainability, diversity, simplicity, and customization [8] Group 1: Intelligent Development - Intelligent manufacturing will be a key direction for the future of automatic bagging machines, integrating more intelligent control systems for real-time monitoring and adjustments [1] - The incorporation of data collection and analysis will enhance production efficiency and reduce labor costs while improving product quality consistency [1][6] Group 2: Environmental Sustainability - The use of eco-friendly materials will become a significant trend, with companies seeking biodegradable and recyclable packaging solutions [3] - This shift aligns with global environmental protection efforts and meets the growing consumer demand for sustainable products [3] Group 3: Technological Diversity - Future automatic bagging machines will offer diverse designs and functionalities, catering to different product characteristics [5] - Custom packaging solutions will be developed for fragile items and food products, adhering to safety standards [5] Group 4: Simplified Operation and Maintenance - Advances in technology will lead to lower failure rates and reduced maintenance needs for automatic bagging machines [5] - User-friendly interfaces will allow operators to easily manage the machines with minimal training, decreasing reliance on highly skilled personnel [5] Group 5: Customization and Market Competitiveness - Personalization will become an important trend, with manufacturers needing to innovate and provide tailored packaging solutions based on specific customer requirements [5] - This flexibility will enhance market competitiveness and meet the increasing consumer demand for personalized products [5] Group 6: Integration with IoT - The combination of automation and networking through IoT technology will enable real-time connections between automatic bagging machines and other production line equipment [6] - This integration will optimize production efficiency and reduce costs, positioning automatic bagging machines as essential components of the overall production system [6]

1 | | 以及个性化制剂的兴起，对生产设备提出了更高的灵活性和合规性 | | --- | --- | | | 要求；带量采购和一致性评价的推进，促使仿制药生产走向标准化， | | | 对设备的精度和一致性提出了新的挑战。国产替代进程加速，高端 | | | 市场逐步实现渗透。 | | | 2、智能化、数字化生产成为核心方向 | | | 智能制药工厂建设加速推进：MES 系统、SCADA 系统、智能机器人逐 | | | 渐普及应用。数据可追溯性成为 GMP 合规的核心要素：生产过程的 | | | 自动记录、审计追踪、电子签名等功能已不可或缺。设备远程监控 | | | 与预测性维护相结合：设备不再仅是硬件设施，而是集成了控制系 | | | 统与数据平台的高度智能化单元。 | | | 2025 年 3 月 17 日，国家药监局发布了《药品生产质量管理规范（2010 | | | 年修订）》无菌药品附录（征求意见稿），旨在推动无菌药品生产 | | 交流内容 | 行业的高质量发展。此次修订意在实现药品检查标准与 PIC/S 标准 | | | 的协调统一，以契合国际药品监管的先进理念和要求，从而提升我 | | | 国无菌药 ...

【华泰计算机】HIMS：25Q1业绩超预期，复合司美风险解除，建议重点关注 25Q1业绩超预期：收入5.86亿美元，同比+111%（指引：5.2-5.4亿)；净利润4950 万美元，同比+344.7%；调整后EBITDA为9105.7万美元（指引：5500-6500 万美元），同比+181.5%，调整后EBITDA利润率15.5%。 核心指标： ①订阅用户236.6万 公司预计将在25Q2末完成之前使用复合司美格鲁肽的订阅用户向其他替代品的完全过渡，将导致Q2收入环比一次 性下降，但公司有信心在今年下半年继续保持增长势头。 #公司复合司美格鲁肽产品停售的风险将在Q2一次性释放，公司已与诺和诺德建立战略合作关系，合作品牌司美 格鲁肽，且未来有可能和更多的品牌药企建立合作关系。 【华泰计算机】HIMS：25Q1业绩超预期，复合司美风险解除，建议重点关注 25Q1业绩超预期：收入5.86亿美元，同比+111%（指引：5.2-5.4亿)；净利润4950 万美元，同比+344.7%；调整后EBITDA为9105.7万美元（指引：5500-6500 万美元），同比+181.5%，调整后EBITDA利润率15.5%。 核心 ...

"你用它用得越多，它就越懂你！"杨元庆表示，"天禧让你更聪明！"（文猛） 新浪科技讯5月7日上午消息，在今日举行的2025联想创新科技大会（Tech World）上，联想集团董事长 兼CEO杨元庆在与"联想AI挚友"大张伟互动时表示AI正变得越来越强大，但他不会取代人类，未来AI 时代人类卷的是创造力，今后他会让人类天马行空，让AI负重前行。 会上，联想集团重磅发布面向个人与企业的"超级智能体"——天禧个人超级智能体，以创新突破加速混 合式AI的全面落地。凭借感知与交互、认知与决策、自主与演进三大核心能力，超级智能体将成为个 性化AI的超级入口，助力个人释放创造力，帮助企业激发新增长动能。 据杨元庆介绍，天禧超级个人智能体具备三大核心功能： • 感知与交互：天禧实现了多模态感知和意图驱动的自然交互，比如当你用手机刷到朋友圈里有好友分 享的游记很吸引人，就可以用语音告诉天禧"这地方看起来不错，找时间去一趟"。天禧立即能激活智能 情境感知功能，识别出照片中的景点信息，根据你习惯的度假时间，以及日程表上的空闲时段，提出度 假时间候选，并通过自然交互确认你的精准意图。 • 认知与决策：天禧能调用跨设备数据所整合的个人 ...

Group 1 - The "May Day" holiday in Shandong has seen a rise in personalized cultural and tourism consumption trends, shifting from mere sightseeing to fulfilling personal "wish lists" during travel [2][3] - The Taishan scenic area experienced a peak in visitor numbers, with 76,000 tourists entering on May 1 alone, highlighting the growing interest in immersive experiences [2] - The Le Ling Film City catered to visitors' desires for immersive experiences by allowing them to participate in film production activities, attracting 46,800 visitors on the first day of the holiday [2] Group 2 - Various cities in Shandong hosted comic exhibitions, which attracted many enthusiasts and stimulated local tourism and hospitality sectors [3] - Family-oriented travelers showed a preference for relaxing vacations, with 45% of visitors to Jiuru Mountain being families, an increase of 10 percentage points from previous years [3] - The Jiuru Mountain scenic area introduced themed activities that engaged families, with an average daily participation of over 3,000 in flower art and chocolate-making workshops [3] Group 3 - Historical towns like Qingzhou Ancient City and Tai'erzhuang Ancient City saw increased visitor engagement through innovative cultural experiences, such as immersive performances and interactive activities [4] - The holiday also marked a peak in inbound tourism, with significant numbers of South Korean tourists arriving at ports like Yantai and Weihai, facilitated by relaxed visa policies [4] - The ease of travel between China and South Korea has encouraged business collaborations, as noted by a South Korean visitor planning to strengthen ties with local enterprises [4]

"五一"假期，在味蕾游、演出游、赶海游等多样玩法推动下，人们出游热情高涨，文旅热度创近年 新高。江苏智慧文旅平台监测显示，5月1日至5月5日16时，全省纳入监测的644家A级旅游景区、195个 省级以上乡村旅游重点村、75家夜间文旅消费集聚区和84家博物馆，去重后共接待游客3533.02万人 次，游客消费总额达162.72亿元，同比分别增长15.62%和14.79%。 拼假，让游玩周期更长 这个假期，延长假期或"请4休11"拼假的趋势较去年更为显著，返程高峰期延后，整体游玩周期同 比拉长。 小长假与签证利好政策叠加，出境游市场强劲增长。各大平台数据显示，出境游方面，人均预订量 同比大增，延续去年"五一"的相同态势，表明消费者更倾向于一次出游玩得更深入、体验更丰富。 飞猪数据显示，出境游机票、酒店、邮轮等商品预订量激增，国际邮轮预订量同比增长超60%。江 苏游客的出境游机票订单量同比增长40%。日本、泰国、韩国、马来西亚及中国香港等是出境游热门目 的地；冰岛、匈牙利、希腊、沙特阿拉伯、挪威等"12小时飞行圈"目的地增速较快，预订量同比增长超 170%。 南京吴女士和两个闺蜜请了5月6日至9日4天假，4月30日出 ...

Castle Biosciences (CSTL) Q1 2025 Earnings Call May 05, 2025 04:30 PM ET Speaker0 Good afternoon and welcome to Castle Biosciences First Quarter twenty twenty five Conference Call. As a reminder, today's call is being recorded. We will begin today's call with opening remarks and introductions, followed by a question and answer session. I would like to turn the call over to Camilla Zuccaro, Vice President of Investor Relations and Corporate Affairs. Please go ahead. Speaker1 Thank you, operator. Good afterno ...