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Core Insights - Axsome Therapeutics is collaborating with the Alzheimer's disease advocacy community to raise awareness about the increasing impact of Alzheimer's disease in the U.S. and the significance of brain health during Alzheimer's & Brain Awareness Month [1][2] Industry Overview - There are currently over 7 million Americans living with Alzheimer's disease, a number projected to rise to approximately 14 million by 2060 [2] - Alzheimer's disease is the most common form of dementia, characterized by cognitive decline and various behavioral symptoms [2] - Nearly 12 million individuals serve as caregivers for those affected by Alzheimer's disease, highlighting the extensive burden on public health [2] - The Global Burden of Disease classification indicates that Alzheimer's disease has escalated from the 12th to the 6th most burdensome disease in the U.S. from 1990 to 2016, based on disability-adjusted life years (DALYs) [2][8] Company Initiatives - Axsome Therapeutics is actively participating in raising awareness and sharing resources related to Alzheimer's disease, alongside advocacy and patient communities [2] - The company is involved in scientific and medical conferences throughout the year to further its mission [2] Research and Development Focus - Axsome Therapeutics is dedicated to addressing central nervous system (CNS) disorders through innovative treatments, focusing on novel mechanisms of action to improve patient outcomes [3][5] - The company's neuroscience portfolio includes FDA-approved treatments for various conditions, including major depressive disorder and narcolepsy [5]

Core Insights - The presentation titled "The New Frontier of Longevity Science: Living Well Beyond Your Years" will be led by Dr. Jeffrey A. Lieberman and Dr. David A. Sinclair, focusing on advances in longevity science and the potential to extend human lifespan beyond 100 years while maintaining quality of life [2][3] Group 1: Presentation Details - The event will take place on March 10, 2025, from 2:30 p.m. to 3:30 p.m. at the JW Marriott Austin as part of SXSW 2025's Health & MedTech Track [3] - Following the presentation, Dr. Lieberman will sign copies of his book "Malady of the Mind: Schizophrenia and the Path to Prevention" at the SXSW Bookstore [4] Group 2: Speakers' Backgrounds - Dr. Jeffrey A. Lieberman is a clinical neuroscientist and psychiatrist known for his research on brain disorders and mental illness, with over 800 scientific articles published and cited more than 100,000 times [5] - Dr. David A. Sinclair is a Professor of Genetics at Harvard Medical School, recognized for his research on aging and age-related diseases, with over 180 peer-reviewed articles published and cited over 97,000 times [6][8] Group 3: Key Topics of Discussion - The presentation will cover pivotal advancements in medicine, including human genome sequencing and the discovery of Sirtuin genes, which have made altering the aging process scientifically plausible [7] - It will also discuss holistic strategies and pharmaceutical therapies aimed at enhancing health and targeting aging at the cellular level [7] - Enhanced therapeutic strategies for brain longevity will be explored, including techniques like transcranial magnetic stimulation and psychedelics [7]