Core Viewpoint - The article emphasizes the importance of high-standard connectivity of market facilities as a foundational prerequisite for breaking geographical barriers and accelerating the flow of factors, which is essential for building a unified national market [1]. Infrastructure Connectivity - The construction of the Tianshan Victory Tunnel, the longest highway tunnel in the world, is expected to significantly reduce logistics costs by approximately 70 million yuan for logistics companies in Xinjiang [1]. - The integration of transportation networks, including highways, railways, and airways, is enhancing the efficiency of the flow of people, vehicles, and goods across regions [2]. - The implementation of multimodal transport solutions, such as the "Hefei-Ningbo Zhoushan Port" sea-rail intermodal service, has reduced transit times for large export shipments from 40 days to 27 days [3]. Digital and Soft Connectivity - The introduction of virtual service windows allows businesses to complete administrative tasks remotely, enhancing the efficiency of inter-regional business operations [7]. - The establishment of a multi-level interconnected government data sharing platform aims to facilitate cross-regional and cross-departmental data sharing, improving the overall experience for businesses and citizens [7]. - The promotion of electronic procurement platforms has enabled suppliers to sell across the province with a single registration, significantly increasing the number of available products and suppliers [9]. Economic Integration and Resource Flow - The development of a unified infrastructure system supports both domestic and international market connections, facilitating the flow of resources and goods across regions [14]. - The successful transportation of high-value products via the China-Europe Railway Express demonstrates the growing sophistication of logistics networks connecting China with Central Asia [14]. - The construction of the Pinglu Canal is expected to enhance trade routes from the southwestern region of China to Southeast Asia, further integrating domestic and international markets [14][15]. Future Outlook - The continuous improvement of infrastructure and digital platforms is anticipated to enhance the efficiency of economic circulation, fostering stronger development momentum in the future [15].

Core Viewpoint - The recent updates to the prospectus for Baiaosaitu-B (02315.HK) have reignited interest in its cross-market listing process, highlighting the complexities faced by domestic innovative pharmaceutical companies in balancing technological breakthroughs and commercial realization [2] Business Overview - Baiaosaitu, founded in 2009, focuses on providing innovative model animals and preclinical pharmaceutical research services based on its proprietary gene editing technology, with a core strategy centered around the "thousand mice, ten thousand antibodies" initiative [3][5] - Currently, the company has 10 drug pipelines, with 5 in clinical trials and the rest in preclinical development, indicating that commercial production has not yet commenced for any products [3] Financial Performance - The company's revenue has shown a steady increase, reaching 534 million yuan, 717 million yuan, and 980 million yuan over the past three years, while the net profit improved from a loss of 602 million yuan to a profit of 34 million yuan in 2024 [3][4] - Despite the positive turnaround, the cumulative unabsorbed losses still stand at 1.754 billion yuan as of the end of the reporting period [3] Revenue Structure - The revenue primarily relies on four segments: model animal sales, antibody development, preclinical pharmacology and efficacy evaluation, and gene editing services [3] - The antibody development segment has consistently reported losses, with net profits of -399 million yuan, -532 million yuan, and -319 million yuan from 2021 to 2023, while the innovative drug development segment also incurs annual losses of around 200 million yuan [5][6] Client Dependency - A significant portion of the company's revenue from antibody development comes from related parties, with 27.81% of total antibody development income derived from major clients, raising concerns about the independence of its business operations [6][7] R&D Investment and Team Dynamics - The company has invested a total of 2.055 billion yuan in R&D from 2021 to 2024, but there has been a noticeable decline in investment intensity, with R&D expenses dropping over 30% in 2024 compared to the previous year [8] - The R&D team has seen a drastic reduction in size, from 627 members at the end of 2022 to 337 by the end of 2024, compounded by the departure of key management personnel [8] Patent Disputes - Baiaosaitu is currently embroiled in a patent dispute with Heptares Therapeutics, which could pose risks to its future technological development and commercial strategies [9][10] Financing and Debt Pressure - The company has faced increasing debt pressure, with the asset-liability ratio rising from 58.9% in 2022 to 65.28% in 2024, indicating financial strain compared to industry peers [12][13] - The actual controller has resorted to personal borrowing to support the company, which raises concerns about the long-term implications of such financial strategies [14][15]

欢迎扫描下方二维码关注： 供稿：德宏税务 来源云南税务 欢迎扫描下方二维码关注： 温馨提醒：蓝色柳林财税室为非官方平台，是由编者以学习笔记形式建立的平台，所有笔记写作记录的文章及转发的法律法规仅供读者学习 参考之用，并非实际办税费的标准，欢迎交流学习，共同分享学习经验成果。文章版权归原作者所有，如有不妥，请联系删除。 税务机关对涉税专业服务实行分类管理。 涉税专业服务包括一般涉税专业服务和特定涉 税专业服务。 船洗税专业服 其他税务事项代办 其他税务代理 特定涉税专业服务 税务合规计划 洗税鉴证 纳税情况宙查 ③ 涉税专业服务需要报送 0) 哪些信息? 何时报送? 税务机关应当加强对涉税专业服务机构 及涉税服务人员的实名制管理，涉税专业服 务机构及涉税服务人员应当以真实身份提供 涉税专业服务。 涉税专业服务机构应当于首次提供涉税 专业服务前，如实向税务机关报送机构及其 涉税服务人员的基本信息，并根据实际情况 及时更新相关信息。 依照法律法规、部门规章规定提供涉税 专业服务的其他人员，应当于首次提供服务 前，向户籍所在地、经常居住地或者提供服 务所在地的主管税务机关如实报送本人的基 本信息。 涉税专业服务机构及 ...

【导读】瑞斯康达董事长和董事被采取刑事强制措施 中国基金报记者 李智 "专网通信"案余波仍在。 7月7日，瑞斯康达发布公告称，因涉嫌违规披露、不披露重要信息罪，北京市公安局朝阳分 局决定对公司董事长兼总经理李月杰和董事朱春城采取刑事强制措施。 董事长和董事被采取刑事强制措施 7月7日，瑞斯康达发布公告称，收到相关人员家属通知，因涉嫌违规披露、不披露重要信息 罪，根据《中华人民共和国刑事诉讼法》第八十二条的规定，北京市公安局朝阳分局决定对 公司董事长兼总经理李月杰和董事朱春城采取刑事强制措施，其中朱春城已被取保候审。 瑞斯康达表示，因董事长兼总经理李月杰被采取刑事强制措施无法正常履行相关职责，为保 证公司经营管理工作的正常开展，在李月杰无法履职期间，特指定公司董事兼副总经理韩猛 代行董事长及总经理职责。 瑞斯康达应当知悉专网通信是没有业务实质的虚假自循环业务。 上述行为导致瑞斯康达披露的2019年至2020年年度报告存在虚假记载，2019年虚增营业收 入3.51亿元，虚增营业成本2.88亿元，虚增利润总额6378.67万元；2020年虚增营业收入 2.81亿元，虚增营业成本2.28亿元，虚增利润总额5345.2 ...

有关数据显示，我国已累计培育专精特新"小巨人"企业1.46万家，其中A股上市企业超过1000家，其研 发强度、毛利率和营收增长率均显著高于A股平均水平。 中小企业"排头兵" 专家表示，中小企业是经济活力与韧性的重要源泉，而专精特新"小巨人"企业则是中小企业发展的"排 头兵"，在推进新型工业化、发展新质生产力中具有重要支撑作用。 专精特新企业"小而专"，具有专业化、精细化、特色化、创新型的特征。"小巨人"企业更是其中的佼佼 者，这些企业位于产业基础核心领域和产业链关键环节，以创新能力突出、核心技术掌握度高、细分市 场占有率领先、质量效益优良而著称。 有关数据显示，我国累计培育专精特新"小巨人"企业1.46万家，这些"小巨人"企业中近九成是制造业企 业，超八成分布在集成电路、航空航天等战略性新兴产业链上，超九成为国内外知名大企业的配套供应 商。尤其在人工智能、低空经济等未来产业，我国的"小巨人"企业数量就接近5000家。 在过去的2024年，专精特新"小巨人"企业在专利创新方面表现突出，拥有发明专利数量32.74万项，户 均22.3项，占全国企业发明专利总量的11%。专精特新"小巨人"企业发明专利密度领先，每千名 ...

作 者丨王峰 编 辑丨周上祺 少见的高温天气下，高校学生宿舍如何"避暑"话题的热度居高不下。在往常颇为凉爽的东北 地区、北方沿海地区，那些宿舍没装空调的大学生发现今年酷热难眠。据报道，青岛大学7月 7日凌晨发布情况说明称，7月6日浮山校区一物业工作人员在值班室被发现身体情况异常，急 救人员抵达现场确认其已不幸离世。有青岛大学保卫处工作人员对媒体表示，"（准备）安空 调的计划好几年了，现在正在装，已经开始装了，（宿舍）都装。" 很多高校校园历史悠久，但学生宿舍设施条件因此受限，最突出的表现之一就是没有空调。 高校学生宿舍的面积有限，布局集中，通风不好，同时人数较多，所以炎热天气下学生宿舍 的热感可能比家里、办公室更强。随着高校办学条件和人们生活条件的提高，只要努力做到 节约用电、绿色低碳，学生宿舍装空调已不是奢侈行为，而是提高学生校园体验的应有之 义。 宿舍也不仅仅是学生休息的场所，而渐渐成为一个综合性育人平台，特别是书院制在国内高 校中日渐流行，集学习、社交、文化、素质拓展等功能为一体的住宿式书院，一个书院坐拥 一处独立空间，这里既是不同院系学生共同生活的宿舍，同时也有健身房、会议室、演讲 厅，在浸润式环境下 ...

Core Insights - The article highlights a significant breakthrough in the data intelligence sector with the launch of a new generation of intelligent agents by Baidang Co., Ltd, marking a milestone in their Data Intelligence strategy [1][3] - The intelligent agent matrix includes transaction management, financial business, and operational decision-making agents, which are seen as essential for unlocking data value in enterprises [1][2] Group 1: Intelligent Agents Overview - The transaction management agent can parse over 200 types of global invoice formats in seconds and integrates over 30,000 international tax rules, addressing compliance challenges for multinational companies [1][2] - The financial risk intelligence agent monitors over 3,000 compliance indicators by integrating 18 data sources, enabling the identification of risks such as false trade and tax anomalies, and automatically generates response plans [2] - The financial marketing agent analyzes multimodal information to create enterprise profiles, optimizing product matching and enhancing marketing precision and conversion rates [2] Group 2: Strategic Vision and Industry Impact - The CEO of Baidang emphasizes that the core value lies in transforming data-driven decision-making from reports to actionable insights, indicating a shift towards modular intelligent agents rather than single general models [3] - The approach of breaking down complex scenarios into specialized intelligent agents not only lowers implementation barriers but also enhances the precision of solutions [3] - The industry is witnessing a trend towards "business expert-level AI" as companies like Baidang deepen their focus on scenario-based intelligent agents, indicating a service upgrade in enterprise solutions [3]

A股专精特新"小巨人"公司超1000家 专精特新企业"小而专"，具有专业化、精细化、特色化、创新型的特征，"小巨人"企业更是其中的佼佼者，这些企业位于产业基础核心领域和产业链关键环 节，以创新能力突出、核心技术掌握度高、细分市场占有率领先、质量效益优良而著称。 截至2025年6月底，我国累计培育专精特新"小巨人"企业1.46万家，其中A股上市公司超过1000家。 A股将发布专精特新系列指数！ 7月7日，上交所与中证指数公司分别宣布，将于7月21日正式发布上证科创板专精特新指数、上证专精特新指数及中证专精特新100指数。同日，深交所 和深 圳证券信息有限公司宣布，将于7月21日发布深证专精特新指数（代码：399268）、创业板专精特新指数（代码：399267）。 这一系列指数的推出，旨在为市场提供更丰富的专精特新上市公司表现基准，引导资金流向创新驱动型中小企业，助力专精特新企业高质量发展。 这些企业虽然市值较小，但具有较强的创新属性。数据显示，A股专精特新"小巨人"上市公司目前平均市值约67亿元；2024年，平均营业收入约13亿元，研 发强度（10.4%）、毛利率（31.6%）和营收增长率（9.8%）均显著高于 ...

★ 宏观动态 ★ 据南方+，近日，天河区在环五山创新策源区项目中，在天河区委、区政府和广州市规划和自然资源局的指导 下，市规划和自然资源局天河区分局（天河区土地开发中心）成功开出面额高达1亿元的房票。这不仅是天河 区自主实施储备项目发出的首宗房票，而且刷新了广州市单张房票面额的最高纪录，标志着天河区落实市委、 市政府"拼经济"核心工作部署取得重要进展。目前，被收储方已成功运用亿元房票，签订物业购买合同。 深交所：定于7月21日发布深证专精特新指数、创业板专精特新指数 7月7日，深交所发布深证专精特新等2条指数的公告。深圳证券交易所和深圳证券信息有限公司定于2025年7月 21日发布深证专精特新指数（简称深小巨人，代码399268）、创业板专精特新指数（简称专精特新，代码 399267）。上述2条指数均采用自由流通市值加权，于每年6月、12月的第二个星期五的下一个交易日进行样本 股定期调整，并通过深交所行情系统计算发布。 中证专精特新100指数将于7月21日正式发布 国家外汇管理局：受汇率折算和资产价格变化等因素综合作用，6月外汇储备规模上升 国家外汇管理局统计数据显示，截至2025年6月末，我国外汇储备规模为 ...

宏观研究 证 券 研 究 报 告 【每周经济观察】 ❖ 一、景气向上： 1）服务消费：航班出行有所上行。7 月前 5 日，国内航班执行数为 1.43 万架 次，同比+4%。6 月为 1.28 万架次，同比+0.8%。 2）土地溢价率：低位反弹。6 月 29 日当周，百城土地溢价率回升至 7.8%。近 三周平均为 4.3%。5 月为 4.93%。 3）物价："反内卷"带动煤炭和地产基建类价格上涨。山西产动力末煤(Q5500) 秦皇岛港平仓价、螺纹钢上海现货价、铁矿石价格指数:62%Fe:CFR 中国北方、 南华玻璃指数分别上涨 0.5%、2.9%、2%、0.7%。 ❖ 二、景气向下： 1）华创宏观 WEI 指数：仍在较高位置。截至 6 月 29 日，该指数为 6%，较 6 月 22 日的 7.63%下行 1.63 个点，但仍在较高位置。6 月 29 日当周，商品房成 交面积、秦皇岛煤炭吞吐量、沥青开工率、钢厂线材产量等指标普遍下行。4 月以来，指数上行的主要驱动因素是沥青开工率、乘用车批零和商品房成交面 积。 2）地产销售：商品房住宅销售降幅扩大。我们统计的 67 个城市，7 月前 4 日， 商品房成交面积同比 ...