Core Viewpoint - Tonghua Dongbao (600867.SH), a major domestic insulin manufacturer, has significantly revised its 2024 annual performance forecast, indicating a substantial shift from profit to loss due to various factors including price reductions from a new round of insulin procurement and legal liabilities [1][2][3][4] Financial Performance Summary - The company now expects a net profit attributable to shareholders of approximately -42.72 million yuan for 2024, a decrease of about 1.211 billion yuan or 103.66% year-on-year [1] - The forecast for net profit excluding non-recurring gains and losses is now -9.1954 million yuan, down approximately 1.177 billion yuan or 100.79% compared to the previous year [1] - In January 2024, the initial forecast estimated a profit of 40.53 million yuan, which would have represented a decrease of about 1.127 billion yuan or 96.53% year-on-year [1] Operational Adjustments - The decline in net profit is attributed to the impact of a new insulin procurement policy, which led to price reductions and inventory adjustments by commercial clients, resulting in decreased sales revenue [1] - The company has terminated the clinical research and development of the THDB0207 injection project, which is expected to reduce profits by 270 million yuan in 2024 [2] Legal and Financial Liabilities - The company is required to pay 61.31 million yuan in damages to Ganli Pharmaceutical due to a trademark infringement lawsuit, which was previously estimated at 30 million yuan [2] - This legal ruling necessitated an adjustment in the company's financial liabilities and losses, impacting the overall profit forecast [2] Additional Financial Adjustments - The second revision of the performance forecast indicates a shift from profit to loss for both net profit attributable to shareholders and net profit excluding non-recurring gains and losses [3] - The company plans to transfer three R&D projects from its subsidiaries, which is expected to affect deferred tax assets and reduce net profit by 52.74 million yuan [3] - The previously recognized loss of 254 million yuan related to the THDB0207 project has been adjusted to be classified as a regular loss rather than a non-recurring one, impacting the net profit by 215 million yuan [3] Market Reaction - The repeated adjustments to the performance forecast within a short span of three months have raised concerns and skepticism in the market regarding the company's financial stability and operational transparency [4]

长江商报消息 ●长江商报记者 沈右荣 国产胰岛素"双雄"之一的通化东宝（600867.SH）业绩再变脸。 4月27日晚，通化东宝发布业绩预告更正公告。更正后的业绩为，2024年，公司预计实现归属于母公司 股东的净利润（简称"归母净利润"）约为亏损4272.32万元，同比下降103.66%；预计实现扣除非经常性 损益的净利润（简称"扣非净利润"）为亏损919.54万元，同比下降100.79%。 这是通化东宝年内第二次更正2024年度经营业绩预告。 今年1月20日，公司预计归母净利润、扣非净利润均大幅下降，但处于盈利状态。今年2月27日，公司更 正后的业绩，较上年同期进一步下降，此时，仍然是盈利的。 如今，在2024年年度报告披露前夕，通化东宝再度更正业绩预告，归母净利润、扣非净利润均由盈转 亏。 业绩预告频繁更正，涉及研发项目终止、侵权官司败诉、资产转让等多方面因素。其中，因为侵犯商标 权，公司被判赔付6131.21万元。 年度亏损，这还是通化东宝自2005年以来的首次。2023年，通化东宝盈利超过11亿元。 值得一提的是，通化东宝的大股东质押率达95.20%。 年报披露前2天再更正预告 在年度报告披露的前2天 ...

Core Insights - The company reported a significant decline in both revenue and net profit for the year 2024, indicating substantial challenges faced during the period [1][2][3] Financial Performance - Revenue for 2024 was 2.549 billion yuan, down 11.98% from 2.896 billion yuan in the previous year, with the core in vitro diagnostic products segment also experiencing a similar decline [2] - Net profit attributable to shareholders was 127 million yuan, a sharp decrease of 59.44% compared to 313 million yuan in the previous year, primarily due to reduced revenue and a goodwill impairment loss of 94 million yuan [3] - The net profit excluding non-recurring items was 138 million yuan, down 56.20% from 316 million yuan, indicating challenges in the core business profitability [4] - Basic earnings per share fell to 0.2091 yuan, a decrease of 59.29% from 0.5136 yuan, reflecting a decline in shareholder returns [5] Expense Analysis - Sales expenses slightly decreased to 647 million yuan, a minor reduction of 0.86%, suggesting inefficiencies in marketing expenditures [6] - Management expenses decreased by 10.37% to 165 million yuan, indicating effective internal cost control measures [7] - Financial expenses were reduced by 29.50% to 16.43 million yuan, reflecting improved debt management [8] Cash Flow Analysis - Net cash flow from operating activities decreased by 29.70% to 634 million yuan, indicating potential issues in sales collections [11] - Net cash outflow from investing activities increased by 34.67% to -677 million yuan, primarily due to increased investments in the IVD Tianfu Industrial Park [12] - Net cash outflow from financing activities increased by 17.00% to -127 million yuan, highlighting pressures from dividend distributions [13] R&D and Innovation - R&D expenses remained stable at 323 million yuan, reflecting the company's commitment to innovation [10] - R&D investment for 2024 was 419 million yuan, accounting for 21.91% of self-owned product revenue, indicating a focus on product development [14] - The number of R&D personnel increased from 1,172 to 1,221, enhancing the company's innovation capabilities [15]

湖南方盛制药股份有限公司 HUNANFANGSHENG PHARMACEUTICAL CO., LTD. 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重 大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 根据《上海证券交易所上市公司自律监管指引第 3 号——行 业信息披露》之《第六号—医药制造》《关于做好主板上市公司 2024 年第一季度报告披露工作的重要提醒》的相关规定，湖南 方盛制药股份有限公司（以下简称"公司"）现将 2025 年第一 季度主要经营数据披露如下： 一、报告期主要经营数据（单位:元 币种:人民币） | | | | 主营业务分行业情况 | | | | | --- | --- | --- | --- | --- | --- | --- | | 分行业 | 营业收入 | 营业成本 | 毛利率% | 营业收入比 上年增减 | 营业成本比 上年增减 | 毛利率比上年增减 | | 工业小计 | 390,041,365.07 | 105,304,938.38 | 73.00% | -1.78% | 13.28% | 减少 3.59 个百分点 | | 医疗业务及其他 | ...

证券代码：002907 证券简称：华森制药 重庆华森制药股份有限公司 投资者关系活动记录表 编号：2025-003 投资者关系活动类别 特定对象调研 分析师会议 媒体采访 业绩说明会 □新闻发布会 □路演活动 □现场参观 □其他 参与单位名称及 人员姓名 深圳市林园投资管理有限责任公司 董事长林园 上海承风金萍私募基金管理有限公司 董事长余承 成都唯赢投资咨询有限公司 投资总监汪海 等一行 时间 2025 年 4 月 27 日 、2025 年 4 月 28 日 地点 公司 2 楼会议室 上市公司接待人姓名 周智如（证券事务代表） 徐 君（证券事务专员） 刘 璐（证券事务专员） 投资者关系活动 主要内容介绍 一、公司在遵守信息披露制度的前提下，介绍公司经营业 绩、产品布局、市场开发和生产管理等情况，沟通内容与公司 公告内容一致。 二、采取问答方式，由周智如女士负责回答： 1.公司 2025 年一季度增长放缓，具体原因是什么？ 答：在 2025 年一季度，公司实现营业收入 2.39 亿元，整 体收入较上年同期增加 4.62%，收入增速放缓主要为上年同期流 感高发，患者多出现咽喉不适症状，公司权重产品甘桔冰梅片 受 ...

2025年4月26日， 昊海生物发布了2024年年报。 # 财报数据 2024年公司实现营业 收入26.98亿元 ，同比 增长1.64% 。归属于母公司股东的净利润为4.20亿元，同比增 长1.04%。整体毛利率为69.88%，同比下降0.63个百分点。 费用变动 现金流 正式报名：首届全球心血管大会 | 赠送纸质白皮书 合作伙伴征集：2025全球手术机器人大会 昊海生物科技（股票代码：688366.SH / 06826.HK）成立于2007年1月24日，是一家专注于生物医用材料 研发、生产和销售的高科技生物医药企业。公司总部位于上海，注册资金1.2亿元人民币，主要从事生物材 料、生物制剂、基因工程药品的研发、生产和销售。 昊海生物科技的主营业务涵盖以下领域： 医疗美容与创面护理产品 公司是 国内第一 大手术防粘连剂生产商，2023年市场份额为28.82%，连续十七年稳居市场首位。 玻尿酸产品 ：公司是国内知名玻尿酸生产商之一，自主研发掌握了单相交联、低温二次交联、线性无颗 粒化交联以及有机交联等交联工艺。第一代产品"海薇"、第二代产品"姣兰"和第三代产品"海魅"已获得 市场广泛认可。 表皮修复基因工程制剂 ...

证券代码：002262 证券简称：恩华药业 江苏恩华药业股份有限公司投资者关系活动记录表 编号：2025-002 | 投资者关系活动 | √特定对象调研 □分析师会议 | | --- | --- | | 类别 | □媒体采访 □业绩说明会 | | | □新闻发布会 □路演活动 | | | □现场参观 √其他 参会股东调研 | | 参与单位名称及 | 国盛证券：胡偌碧；国金证券：刘创；平安证券：韩盟盟；西部证券自营： 李远剑、周密；大成基金：阳洪宇；中信证券：朱家成；易米基金：刘家 | | 人员姓名 | 曦；永赢基金：张晓榕；成都五福源投资管理有限公司：石志伟；林刚、 | | | 杜雄、于满意、王志祥、周长萍、聂凤忠、张安忠、王聪、武文俊、宗宗、 | | | 蒋允刚、杜群飞。 | | 时间 | 2025 年 4 月 25 日上午 10:10-11：10 | | | 徐州市经济技术开发区龙湖西路31号恩华科技大厦3楼301会议室。 | | 地点 | | | 上市公司接待人 | 董事长孙彭生、董事会秘书段保州、财务负责人李岗生、证券事务代表吴 | | 员姓名 | 继业。 | | | 就公司 2024 年度报告及公司 ...

Core Viewpoint - In 2024, Zhendong Pharmaceutical faced multiple operational challenges leading to a significant deterioration in its financial condition, with a reported revenue decline of 18.06% and a net loss of 1.33 billion yuan [1][3]. Financial Performance - The company's total revenue for 2024 was 2.971 billion yuan, down from the previous year [1][3]. - The net profit attributable to shareholders was a loss of 1.329 billion yuan, a substantial increase from a loss of 43.98 million yuan in 2023 [1][3]. - The non-recurring net profit also showed a loss of 686 million yuan, significantly higher than the previous year's loss of 116 million yuan [1][3]. Business Segments - Zhendong Pharmaceutical's two main business segments, pharmaceutical production and sales, and medicinal herb planting, both experienced declines [1][3]. - Revenue from pharmaceutical production and sales was 2.313 billion yuan, a decrease of 20.50% year-on-year [1][3]. - Revenue from medicinal herb planting and sales was 634 million yuan, down 8.99% year-on-year [1][3]. Regulatory Issues - In October 2023, a subsidiary, Landi Pharmaceutical, faced administrative penalties for 32 batches of calcium carbonate D3 granules failing inspections, resulting in a fine of 134 million yuan and a confiscation of illegal gains of 6.18 million yuan [2][7]. - In September 2024, Landi Pharmaceutical initiated arbitration against Zhendong Pharmaceutical for 1.467 billion yuan, leading to a final compensation payment of 500 million yuan by Zhendong [2][6][7]. Shareholder Actions - Since its listing, Zhendong Pharmaceutical has seen significant shareholder sell-offs, with a total of 176.2 million shares sold, amounting to 1.359 billion yuan [2][8]. - The controlling shareholder, Li Anping, has personally cashed out 706 million yuan through share reductions [2][8].

上 市 公 司 医药生物 2025 年 04 月 28 日 仟源医药 (300254) ——戒烟药全年增速超 170%，费率优化抬升利润空间 报告原因：有业绩公布需要点评 买入（维持） | 市场数据： | 2025 年 04 月 25 日 | | --- | --- | | 收盘价（元） | 8.85 | | 一年内最高/最低（元） | 11.86/7.44 | | 市净率 | 8.5 | | 股息率%（分红/股价） | - | | 流通 A 股市值（百万元） | 1,991 | | 上证指数/深证成指 | 3,295.06/9,917.06 | | 注："股息率"以最近一年已公布分红计算 | | | 基础数据: | 2025 年 03 月 31 日 | | --- | --- | | 每股净资产（元） | 1.05 | | 资产负债率% | 64.67 | | 总股本/流通 A 股（百万） | 248/225 | | 流通 B 股/H 股（百万） | -/- | 一年内股价与大盘对比走势： 04-25 05-25 06-25 07-25 08-25 09-25 10-25 11-25 12-25 01-25 ...

本周永安药业、舒泰神和尔康制药等表现较好 [Table_Main] 行业研究|医疗保健 证券研究报告 医疗保健行业周报 2025 年 04 月 28 日 [Table_Title] 即将进入业绩真空期，关注基本面向上板块 ——医药生物行业周报（2025.4.21-2025.4.25） [Table_Summary] 报告要点： 医药板块本周小幅跑赢沪深 300 指数 2025 年 4 月 21 日至 4 月 25 日，申万医药生物指数上涨 1.16%，跑 赢沪深 300 指数 0.78pct，在 31 个申万一级行业指数中排名第 15。 2025 年初至今，申万医药生物指数下跌 0.31%，跑赢沪深 300 指数 3.45pct，涨跌幅在 31 个申万一级行业指数中排名第 13。截至 2025 年 4 月 25 日，医药板块估值为 26.37 倍（TTM 整体法，剔除负值）， 相对于沪深 300 估值溢价率为 141.60%。 医药行业政策风险，产品降价风险，研发进度不及预期风险。 [Table_Invest] 推荐|维持 [Table_ 过去一年PicQuote 市场行情] -19% -10% -1% 8% ...