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PharmaTher Applauds FDA's New Commissioner’s National Priority Voucher (CNPV) Program, Citing Potential to Accelerate its Ketamine Programs for Mental Health, Pain, and Neurological Disorders, and National Security Applications
Globenewswire· 2025-06-18 12:00
Core Insights - PharmaTher Holdings Ltd. is focused on developing ketamine-based therapies and supports the FDA's new Commissioner's National Priority Voucher (CNPV) program to expedite the regulatory review process for its products [1][2][7] - The CNPV program significantly reduces the review time for drug applications from approximately 10-12 months to 1-2 months, allowing for accelerated approval if legal requirements are met [2] - PharmaTher has a robust chemistry, manufacturing, and controls (CMC) package for its ketamine product, with an FDA approval goal date set for August 9, 2025 [3] Clinical Developments - The company has promising clinical data for its ketamine therapies targeting rare and near-rare disorders, including Parkinson's disease and Complex Regional Pain Syndrome [4] - PharmaTher is developing innovative delivery systems such as KETAPATCH™, a microneedle patch, and a wearable pump, which aim to provide easier administration compared to traditional intravenous infusions [4] Regulatory Designations - The FDA has granted five orphan drug designations to PharmaTher for ketamine treatments addressing conditions like Amyotrophic Lateral Sclerosis (ALS) and Rett Syndrome [5] - These designations highlight the company's commitment to addressing critical unmet medical needs, particularly in mental health and pain management [6] Strategic Positioning - PharmaTher aims to leverage the CNPV program to enhance its development timeline and deliver value to patients and shareholders, aligning with national health priorities [7] - The company is positioned to become a leader in the pharmaceutical development of ketamine through its focus on novel, intellectual property-protected delivery systems [7]
How to Bloom When You’re Planted in Two Places | Ezra Freeman | TEDxTSMU
TEDx Talks· 2025-06-17 16:16
[Music] [Applause] [Music] See, I had an amazing family, incredible friends, and I didn't ever feel like anything was missing. by not knowing my birth family or my birth culture. And for as far back as I can remember, my life was full. But our stories, they always run deeper than what we can remember. Ah, over the last four years, what was once just my fun fact has now become a central part of my funky Georgian American life. something that has redefined my every move, given me a new sense of purpose, and h ...
Streaming surpasses combined broadcast and cable viewing for first time ever
CNBC· 2025-06-17 15:13
Core Insights - Streaming services have surpassed the combined share of broadcast and cable TV viewing for the first time, representing 44.8% of total TV viewership in May 2024 [2][10] - The growth of streaming has been significant, with a 71% increase over the past four years, while broadcast and cable viewing have declined by 21% and 39%, respectively [2][4] Streaming Growth Factors - The rise of streaming is attributed to three main factors: the popularity of free ad-supported streaming TV (FAST) channels, the growth of YouTube, and the adaptation of legacy media companies to cater to streaming-centric consumers [4][8] - In May 2021, only five streaming platforms exceeded 1% of total TV viewing, but this number has increased to 11 platforms as of the latest report [4] Popularity of Free Streaming Options - Free channels like Pluto TV, Roku Channel, and Tubi accounted for 5.7% of total TV viewing in May, surpassing any individual broadcast network [5] - YouTube has seen a remarkable 120% increase in viewership since 2021, representing 12.5% of all television viewing in May, marking its highest share to date [6][7] Transformation of Traditional Media - Traditional media companies are increasingly transforming into streaming-first entities, with platforms like Hulu, Paramount+, and Peacock complementing linear TV rather than competing with it [8] - Major media companies are undergoing restructuring, with Warner Bros. Discovery planning to separate into a streaming and studios company and a global networks company, while Comcast is spinning off most of its NBCUniversal cable network portfolio [9] Subscription Service Performance - Netflix has emerged as the leading paid subscription service, with a 27% increase in viewing over the past four years, maintaining its position as the top provider in total TV usage [10]
NEVADA CANYON COMPLETES SALE OF SWALES PROPERTY
Globenewswire· 2025-06-17 13:00
Reno, Nevada, June 17, 2025 (GLOBE NEWSWIRE) -- Nevada Canyon Gold Corp. (OTCQX Markets: NGLD) (The “Company” or “Nevada Canyon”) is pleased to announce the execution of an Asset Purchase Agreement ("APA") with Metals One Nevada Inc., a wholly owned subsidiary of Metals One Plc. (“Metals One”) for the Swales Gold Property Exploration Lease and Option to Purchase Agreement (the "Swales Lease"), located in Elko County, Nevada. Pursuant to the APA between Nevada Canyon and Metals One, Metals One has acquired t ...
How to Build Trustworthy AI — Allie Howe
AI Engineer· 2025-06-16 20:29
Trust is a multifaceted outcome that results when product and engineering teams work together to build AI that is aligned, explainable, and secure. Learn strategies for how to build trustworthy AI and why trust is paramount for AI systems. Trustworthy AI = AI Security + AI Safety Learn about the differences between AI Security and AI Safety and how the three focus areas of MLSecOps + AI Red Teaming + AI Runtime Security can help you achieve both and ultimately build Trustworthy AI. Trustworthy AI Issues in ...
Where Is Home? From Feeling Lost to Finding Myself | Elia Fenaroli | TEDxEatonSquarePrep
TEDx Talks· 2025-06-16 16:03
Where is home. From feeling lost to finding myself. Hello, my name is Ella and I'm a 10-year-old boy from Italy. In the summer of 2021, my whole family and I moved from a small town called Desio in the north of Italy to London.That was a big change. So, why am I standing here today. After nearly 4 years of living in the United Kingdom, I would like to share some thoughts about a very simple question with no easy answer.Where is home. Life in Italy was amazing. I lived in a quiet town near Milan in a house t ...
Dal manicomio alla famiglia: istantanee di rinascita | Giacomo Doni | TEDxPutignano
TEDx Talks· 2025-06-16 15:43
Historical Context & Social Commentary - The presentation explores the history of Italian mental asylums and the social boundaries they represented, aiming to understand and document the experiences of those excluded [3] - The speaker emphasizes the importance of recovering the stories of individuals who lived in these institutions, often reduced to clinical descriptions or names etched in wood [3][5] - The presentation highlights the shift from institutionalization to community-based care, referencing the Basaglia Law of 1978 which mandated the closure of mental asylums in Italy [20] - Before 1978, asylums housed not only the mentally ill but also those deemed "dangerous to themselves or others," including women who didn't conform to social norms, individuals with neurological disorders, illegitimate children, political opponents, and the poor [20][21] Community-Based Care & Therapeutic Approaches - The presentation discusses the therapeutic community model pioneered in the Belgian town of Geel, where individuals with mental illness were integrated into the social fabric [7][14] - The IESA (Inserimento Eterofamiliare Supportato) program in the ASL Torino 3 region of Italy is presented as a modern example of this approach, involving 191 patients and 297 families since 1997 [15] - The program emphasizes the importance of "normal" families, not necessarily medical professionals, in providing a supportive environment for patients [16] - This family-based approach aims to improve patients' independence and social skills, transforming the home into a therapeutic space [16] Individual Stories & Humanization - The story of Armida, a patient who spent her childhood in an orphanage and asylum, is used to illustrate the potential for a new life within a family setting [1][23] - The presentation shares the story of Maura, who was institutionalized at age 11 and later found a supportive family, highlighting the positive impact of family care on her life [16][17] - Maura's experience demonstrates the capacity for individuals with mental illness to offer support and empathy to others, even in times of grief [18]
Mag Mile Capital Secures $10.25 Million in Joint Venture Equity for Chicago Office-to-Multifamily Conversion Project
Globenewswire· 2025-06-16 14:24
Core Insights - Mag Mile Capital has successfully arranged $10.25 million in joint venture equity for a Class A office-to-multifamily conversion project in Chicago [1][2][3] - The equity was secured from an institutional limited partner based in Chicago, with the transaction closing in late May 2025 [2][6] - The project will convert a former Class A office space into 153 Class A multifamily rental apartments [3][4] Company Overview - Mag Mile Capital is a boutique commercial real estate mortgage banking firm headquartered in Chicago, with additional offices in several states [7] - The firm specializes in real estate bridge financing, mezzanine and permanent debt placement, and equity arrangements across various real estate asset classes [7] - Mag Mile Capital has collectively closed over $9 billion in real estate financing during its personnel's combined 32 years of experience in the industry [7] Project Details - The project is located at 111 W. Illinois in the River North neighborhood of Chicago [1][6] - The joint venture aims to fund a portion of the construction costs required for the conversion [3][4] - The transaction is significant as it represents one of the largest office-to-residential conversion projects in Chicago following the Covid-19 pandemic [4] Leadership Commentary - Matt Weilgus, SVP and Head of Originations, emphasized the importance of securing a seasoned institutional capital partner with local market expertise for the project [4] - Rushi Shah, Chairman and CEO, highlighted the significance of long-standing relationships with clients and capital partners in achieving this closing [5] - The company aims to continue delivering tailored financing and equity solutions across all commercial real estate sectors nationwide [5]
Invitation Homes (INVH) 2023 Earnings Call Presentation
2025-06-16 10:19
Investor Presentation Together with you, we make a house a home. I. Executive Summary South Florida June 2023 2 Key Takeaways And Updates We are the nation's premier single-family home leasing company, with an emphasis on the resident experience Phoenix 3 Our May QTD Same Store results reflect continued strong demand and sustained pricing power: New lease rate growth of 7.4%, versus 5.7% in 1Q23 Renewal rate growth of 6.9%, versus 8.0% in 1Q23 Blended rate growth of 7.0%, versus 7.3% in 1Q23 Average occupan ...
Very Possible This Iranian Regime Could Collapse, NUFDI's Khansarinia Says
Bloomberg Television· 2025-06-16 06:45
How vulnerable is the Iranian regime at this point. Well, after 46 years of rule, the Islamic Republic is probably at its weakest moment that it's ever been. I mean, the past few days of Israeli attacks on the Islamic Republic have not only been a significant operational and strategic weakening of this regime, but also a significant psychological weakening of this regime.Ali Khamenei has ruled this country without elections as a one man show, really for 30 years. And the generals who rise up in his armed fo ...