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GRAIL Announces Positive Top-Line Results From The Galleri® PATHFINDER 2 Registrational Study
Prnewswire· 2025-06-18 13:01
Core Insights - GRAIL, Inc. announced positive top-line performance and safety results from the PATHFINDER 2 study, which involved 25,578 participants and aimed to evaluate the Galleri multi-cancer early detection test [1][5] Group 1: Study Results - The PATHFINDER 2 study demonstrated that adding Galleri to standard cancer screening significantly increased cancer detection rates compared to the previous PATHFINDER study [2] - In the PATHFINDER study, Galleri had a positive predictive value (PPV) of 43%, specificity of 99.5%, and cancer signal origin (CSO) accuracy of 88%. The PATHFINDER 2 study showed a substantially higher PPV while maintaining consistent CSO accuracy and specificity [3] Group 2: Safety and Regulatory Aspects - No serious safety concerns were reported in the PATHFINDER 2 study, indicating a favorable safety profile for the Galleri test [4] - GRAIL plans to submit the PATHFINDER 2 study results to the U.S. FDA as part of the Galleri premarket approval application, which is currently in process under a Breakthrough Device Designation [5][6] Group 3: Future Directions - Detailed results from the PATHFINDER 2 study are expected to be presented at a leading international oncology meeting later this year [6] - The study aims to evaluate the Galleri test's performance across various measures, including PPV, negative predictive value (NPV), sensitivity, specificity, and CSO prediction accuracy [7]
Beyond Air Stock Dips After Mixed Q4 Results: Here's What To Know
Benzinga· 2025-06-17 20:32
Financial Performance - Beyond Air reported quarterly losses of nine cents per share, beating the analyst consensus estimate of a loss of 12 cents [1] - Quarterly revenue was $1.15 million, missing the Street estimate of $1.39 million, but up from $470,000 in the same period last year [1] Business Development - CEO Steve Lisi stated that commercial momentum is building, reflected in topline results, with LungFit PH now installed and in regular use at over 45 hospitals nationwide [2] - There is increasing recognition among clinicians and administrators of the advantages of Beyond Air's cylinder-free system compared to conventional nitric oxide delivery methods [2] Future Outlook - Beyond Air expects first-quarter revenue to be at least $1.7 million and has issued fiscal 2026 revenue guidance in a range of $12 million to $16 million [3] - Following the earnings report, Beyond Air stock was down 9.16% at 26 cents in extended trading after gaining 58.69% in the regular session [3]
Airline Stocks Bounce Back on Monday's Trading: Here's Why
ZACKS· 2025-06-17 18:31
Group 1 - The airline industry has shown a significant recovery, with major players like Delta Air Lines, United Airlines, American Airlines, and Southwest Airlines experiencing stock price increases of 5.14%, 6.11%, 5.11%, and 1.48% respectively on June 17, 2025 [1] - The NYSE ARCA Airline index rose by 3.36% to $55.32, indicating a positive market reaction following the recovery [2] - The decline in oil prices, down about 2% due to easing tensions between Israel and Iran, has positively impacted the profitability outlook for airlines [4][5] Group 2 - The recent rise in airline stocks is viewed as a recovery from a downturn on June 13, 2025, when the NYSE ARCA Airline index fell by 4.3% amid geopolitical tensions that caused oil prices to surge by 7% [6][10] - The easing of the Israel-Iran conflict has alleviated fears of global oil supply disruptions, boosting investor confidence in the airline sector [5][8] - Despite the positive developments, the airline industry continues to face challenges such as delivery delays from Boeing and Airbus, fluctuating passenger demand, rising labor costs, and increased competition from low-cost carriers [9][10]
Verinin Gücü: İstatistikle Dünyayı Anlamak | Fatma Noyan Tekeli | TEDxHBVAL Youth
TEDx Talks· 2025-06-17 16:01
Hoş geldiniz. Aslında ben böyle hayatımla ilgili bir başarı hikayesi anlatmayacağım sizlere. Böyle girişimcilikle ilgili veya mutluluğa giden yollarla ilgili bilgiler veremeyeceğim ne yazık ki.Çünkü o konularda uzman değilim. Eee ismim Fatma Oyan Tekeli. Yıldız Tekif Üniversitesi İstatistik bölümünde öğretim üyesiyim.İstatistikçiyim. En iyi bildiğim şey veri. O yüzden size veriyle ilgili bilgi vermek istiyorum.Veri nedir. Eee, niçin bu kadar önemli. Böyle bir toplantıda, böyle bir platformda, eee, veriyi an ...
Copa Holdings' May 2025 Traffic Improves Year Over Year
ZACKS· 2025-06-17 14:31
Core Insights - Copa Holdings, S.A. (CPA) reported strong traffic numbers for May 2025, driven by high air travel demand, with revenue passenger miles (RPM) increasing year-over-year [1][8] - To meet the rising demand, CPA increased its capacity, with available seat miles (ASM) growing by 7% year-over-year, while RPM surged by 7.5% [2][8] - The load factor improved to 87.6% from 87.3% in May 2024, indicating that traffic growth outpaced capacity expansion [2][8] Company Performance - CPA holds a Zacks Rank of 1 (Strong Buy), with shares rising 18% year-to-date, contrasting with a 10.7% decline in the Zacks Airline industry [3] - Other airlines, such as Volaris and Ryanair, also reported positive traffic numbers, with Volaris showing a 9% increase in capacity but a decrease in load factor, while Ryanair transported 18.9 million passengers, reflecting a 4% year-over-year increase [5][6][9]
Mercurity Fintech Partners with Franklin Templeton to Advance Real-World Asset Tokenization with BENJI Tokens and FOBXX Fund
Globenewswire· 2025-06-17 13:00
Core Viewpoint - Mercurity Fintech Holding Inc. has announced a strategic partnership with Franklin Templeton to integrate the BENJI token and the Franklin OnChain U.S. Government Money Fund into its platform for tokenized real-world assets, aiming to bridge traditional and digital finance [1][6]. Group 1: Partnership Details - The partnership will leverage Franklin Templeton's BENJI token, which provides direct access to the regulated U.S. money market fund FOBXX, combining the stability of government-backed securities with the flexibility of digital assets [2][6]. - This collaboration aims to modernize investment access while maintaining regulatory standards, making institutional-grade financial products more accessible through blockchain technology [6]. Group 2: Operational Benefits - The blockchain-based structure of the BENJI token addresses traditional inefficiencies in money market fund operations, such as reducing settlement times and simplifying asset transfers, while ensuring regulatory compliance [3]. - Mercurity Fintech's platform will allow both institutional and retail investors to access money market opportunities, earn yields on holdings, and facilitate seamless crypto-to-fiat conversions [4]. Group 3: Company Strategy - Mercurity Fintech plans to utilize tokenized treasury products like BENJI to generate returns on capital reserves, enhancing its digital asset ecosystem [5]. - The company's subsidiary, Chaince Securities, will manage investment transactions and advisory services for these tokenized assets, providing compliant distribution and efficient market access [5][8]. Group 4: Company Background - Mercurity Fintech Holding Inc. is a fintech group that offers technology and financial services powered by blockchain infrastructure, aiming to bridge traditional finance and digital innovation [7]. - Chaince Securities, a wholly-owned subsidiary, specializes in investment banking and brokerage services, supporting the vision of integrating traditional finance with blockchain innovation [8]. Group 5: Franklin Templeton Overview - Franklin Templeton is a global investment management organization with over $1.53 trillion in assets under management as of April 30, 2025, and has extensive capabilities in various investment solutions [9].
Oxbridge / SurancePlus to Speak at Yield Day NYC and Attend Permissionless IV
GlobeNewswire News Room· 2025-06-17 12:00
GRAND CAYMAN, Cayman Islands, June 17, 2025 (GLOBE NEWSWIRE) -- Oxbridge Re Holdings Limited (Nasdaq: OXBR) (“Oxbridge Re”), together with its subsidiary SurancePlus, is engaged in the tokenization of Real-World Assets (“RWAs”), initially with tokenized reinsurance securities and in providing reinsurance solutions to property and casualty insurers in the Gulf Coast region of the United States. Today, the company is pleased to announce its upcoming participation in Yield Day NYC and Permissionless IV, two le ...
搜索智能体RAG落地不佳?UIUC开源s3,仅需2.4k样本,训练快效果好
机器之心· 2025-06-17 00:10
当前,Agentic RAG(Retrieval-Augmented Generation)正逐步成为大型语言模型访问外部知识的关键路径。但在真实实践中,搜索智能体的强化学习训练并未展现 出预期的稳定优势。一方面,部分方法优化的目标与真实下游需求存在偏离,另一方面,搜索器与生成器间的耦合也影响了泛化与部署效率。 我们(UIUC & Amazon)提出的 s3(Search-Select-Serve) 是一种 训练效率极高、结构松耦合、生成效果导向的 RL 范式 。该方法使用名为 Gain Beyond RAG (GBR) 的奖励函数,衡量搜索器是否真的为生成带来了有效提升。实验表明,s3 在使用仅 2.4k 训练样本 的情况下,便在多个领域问答任务中超越了数据规模大百 倍的强基线(如 Search-R1、DeepRetrieval)。 论文标题:s3: You Don't Need That Much Data to Train a Search Agent via RL 研究动机 RAG 的发展轨迹:从静态检索到 Agentic 策略 b. Search-R1 :将检索与生成联合建模,以最终答案是否 Exa ...
Why gas prices could climb higher, claiming Social Security payments, how to retire early
Yahoo Finance· 2025-06-16 20:27
Welcome to Wealth. I'm Alec Canal and this is Yahoo Finance's guide to building your financial footprint. Our community of experts will give you the resources, tools, tips, and tricks you need to grow your money.On today's show, we'll check in on oil prices after they jump to their highest level since January. Our very own Nes Fay will explain how that could impact your prices at the pump and more Americans are claiming social security benefits. A financial planner will break down how you should look at tho ...
İnsanın İnsan Olma Serüveni | Ayşe Nevin Yıldız | TEDxHacettepeUniversity
TEDx Talks· 2025-06-16 16:30
Eee, ben, eee, özgeçmişime bakanlar zaten görmüştür. Hacettepe Üniversitesi'nde İletişim Fakültesi'nde öğretim üyesiyim. Eee, temel çalışma alanım insan hakları, eee, medya ve toplumsal cinsiyet mevzusu.Eee, bugün bir ifade özgürlüğü konuşması yaparak aslında bitirmek istiyorum. Eee, çünkü birinci oturumundan, oturumdan beri insanlık tarihinde bizi var edenin aslında birbirimizle konuşmak olduğunu görüyoruz. Yani kültürün kendisi zaten konuşma yeteneği olmayan, dil yeteneği olmayan bir varlıktan değil, insa ...