Summary of Roivant Sciences (ROIV) Conference Call Company Overview - Roivant Sciences is a clinical stage biopharma company focused on developing valuable medicines with a portfolio of late-stage programs [4][5] - The company has approximately $5 billion in cash, primarily from a previous transaction involving an anti T1 antibody [6] Key Programs and Pipeline - **Anti FcRn Franchise**: Developed through subsidiary Immunovant, focusing on indications like Graves' disease and myasthenia gravis (MG) [5][59] - **JAK1/TYK2 Inhibitor**: Targeting dermatomyositis, non-infectious uveitis, and cutaneous sarcoidosis [5] - **PHLD Program**: Known as Mosley Siguat, with significant data expected in the near future [5] - Upcoming phase three readout for dermatomyositis expected in the second half of the year, which could lead to a commercial launch [7][24] Market Opportunities - The dermatomyositis market is estimated to have around 40,000 to 70,000 patients, with the potential for Roivant to be the first oral novel medication in this space [27][28] - The company anticipates a significant commercial opportunity, with pricing expected to be competitive with existing therapies like IVIG [52][51] Business Development (BD) Strategy - The current biotech market presents opportunities for Roivant as valuations decrease and expectations shift [11][12] - The company is exploring indication expansions organically, particularly in the FcRn and JAK1/TYK2 areas [13][14] - Roivant is open to various therapeutic areas, including immunology, respiratory, and rare diseases, while being cautious about competitive dynamics in oncology and gene therapy [20] Regulatory and Clinical Considerations - The company is focused on achieving orphan drug designation for its dermatomyositis treatment, which provides benefits in user fees and FDA engagement [41][42] - The primary endpoint for the phase three trial is a statistically significant improvement in the Total Improvement Score (TIS) [30][40] - Placebo effects are a concern, but the company is implementing strategies to mitigate these risks, including a mandatory steroid taper in the trial protocol [34][39] Immunovant and Future Prospects - Immunovant's lead drug, IMG1402, is in pivotal trials for multiple indications, with promising data supporting deeper IgG suppression leading to better clinical outcomes [59][60] - The company aims to redefine success metrics in MG, moving towards deeper clinical responses rather than just baseline improvements [63][65] - Roivant holds a 58% stake in Immunovant and is optimistic about the potential for multiple blockbuster indications [72][74] Legal Matters - Roivant is involved in patent litigation against Pfizer and Moderna regarding their COVID-19 vaccines, with expectations for a trial in the near future [76][77] Conclusion - Roivant Sciences is positioned for significant growth with a robust pipeline and strategic focus on valuable therapeutic areas, while navigating challenges in the current biotech landscape and legal environment [4][11][76]

Mr. Pedro Escudero CEO and CIO DOMA, Perpetual Capital Management LLC Dear Mr. Escudero, This letter is in response to your letter dated May 9, 2025. YOKNEAM, Israel, May 28, 2025 /PRNewswire/ -- InMode Ltd. (Nasdaq: INMD) ("InMode"), a leading global provider of innovative medical technologies, today sent a letter to DOMA Perpetual Capital Management LLC ("DOMA") CEO and CIO Pedro Escudero in response to issues presented in his public letter dated May 9, 2025. The letter can be viewed here The full text of ...

Core Points - Preferred Bank has announced a new $125 million stock repurchase plan, which has been approved by shareholders [1] - The bank completed its previous $150 million stock repurchase plan, repurchasing a total of 2,146,252 shares at an average price of $70.13 per share [1] - The final tranche of the previous repurchase involved buying back 818,059 shares for $65.7 million [1] Company Overview - Preferred Bank is one of the largest independent commercial banks in California, chartered by the State of California and insured by the FDIC [3] - The bank operates from its main office in Los Angeles and has twelve full-service branches in California, as well as branches in New York and Texas [3] - Preferred Bank offers a wide range of deposit and loan products to commercial and consumer customers, focusing on small and mid-sized businesses, entrepreneurs, and high net worth individuals [3]

Core Viewpoint - The analysis compares Uber and Grab, highlighting Uber's global reach and diversified services against Grab's regional focus and adaptability in Southeast Asia [3][4][9]. Group 1: Uber's Performance and Strategy - Uber's ride-sharing and delivery platforms are experiencing strong demand, contributing to positive financial results [4]. - In Q2 2025, Uber's gross bookings are projected to be between $45.75 billion and $47.25 billion, reflecting a 16-20% growth on a constant currency basis compared to Q2 2024 [5]. - Uber's earnings estimates for 2025 are $2.84, with a year-over-year growth estimate of -37.72%, but a positive outlook for 2026 with a 22.90% growth estimate [6]. - The company is pursuing strategic partnerships to enter the robotaxi market, avoiding high R&D costs, and is actively engaging in acquisitions and geographic diversification [6]. - Uber generated a record $6.9 billion in free cash flow in 2024 and announced a $1.5 billion accelerated stock buyback program, indicating confidence in its business strategy [7]. Group 2: Grab's Growth and Challenges - Grab has successfully adapted to local conditions in Southeast Asia, evolving from a taxi-hailing app to a comprehensive service platform [9]. - In Q1 2025, Grab's On-Demand Gross Merchandise Value (GMV) increased by 16% year-over-year, with expected revenues between $3.33 billion and $3.40 billion for 2025, indicating a 19-22% growth [10]. - Grab has partnered with Amazon Web Services (AWS) to enhance operational efficiency and drive growth across its services [11][12]. - Grab's earnings estimates for 2025 are $0.05, with a significant year-over-year growth estimate of 266.67% [13]. Group 3: Valuation and Market Position - Uber's forward sales multiple is 3.58, above its three-year median of 2.54, while Grab's is 5.78, exceeding its median of 4.85 [16]. - Uber's market capitalization stands at $191.95 billion, positioning it well to navigate economic uncertainties [18]. - Grab, with a market capitalization of $20.5 billion, faces challenges due to its narrower geographical focus and intense competition in the delivery segment [19]. - The analysis concludes that Uber is a more favorable investment compared to Grab, despite both companies currently holding a Zacks Rank of 3 (Hold) [20].

Core Viewpoint - Chevron is positioned as an excellent dividend stock for passive income investors, despite a recent decline in stock price and low oil prices [1][3][13] Financial Performance - Chevron's stock has fallen approximately 16% from its 52-week high, which occurred less than two months ago [1] - Brent crude oil prices are at multi-year lows, impacting Chevron's margins and leading to lower revenue and earnings growth [3] - The company has become more efficient, with expected incremental free cash flow (FCF) of $9 billion by 2026 at a Brent price of $60 per barrel [5] Operational Efficiency - Chevron has the lowest upstream breakeven in its peer group, around the low $30-per-barrel Brent range, outperforming competitors like ExxonMobil and Shell [6] - The company anticipates a 50% increase in Gulf Coast production by 2026, driven by the expansion of its deepwater Anchor project [7] Shareholder Returns - Chevron has consistently executed stock buybacks, with $11.26 billion in 2022, $14.94 billion in 2023, and $15.23 billion planned for 2024 [8] - The company plans to spend $2.5 billion to $3 billion on buybacks in the second quarter of 2024, while maintaining a strong cash return to shareholders [9] - Chevron's quarterly dividend expenditure is around $3 billion, with a 38-year history of increasing dividends, resulting in a yield of 4.8% [10][11] Financial Health - The company's debt ratio stands at 14.4%, which is below its target range of 20% to 25%, indicating a strong balance sheet [12] Investment Outlook - Chevron is viewed as a reliable dividend stock with a strong track record, capable of generating high FCF and supporting future buybacks and dividend increases [13][14]

Group 1: Company Overview - O'Reilly Automotive is primarily a retailer of auto parts, serving both do-it-yourself and professional markets, with approximately 6,400 stores across North America [2] Group 2: Growth Strategies - The company plans to open around 200 new locations in 2025, and same-store sales increased by 3.6% in the first quarter of 2025, contributing to reasonable top-line growth [4] Group 3: Financial Performance - In the first quarter of 2025, O'Reilly's sales increased by 4%, while earnings rose only about 2%, indicating a disparity between sales growth and earnings growth [5][6] - Despite a 4% increase in sales, the company's net income fell from $547 million in Q1 2024 to $538 million in Q1 2025 due to rising selling, general, and administrative costs [8] - Earnings per share increased from $9.20 in Q1 2024 to $9.35 in Q1 2025, attributed to a 3% reduction in share count, despite lower net income [9][10] Group 4: Operational Challenges - The increase in operating costs has been a significant factor affecting profitability, with the earnings advance year over year being around 1.6%, suggesting that stock buybacks only partially mitigated the impact of rising costs [11]

Advanced Micro Devices Inc. AMD is riding its strongest rally in two years – and now, it's firing on all cylinders with a fresh catalyst: a $6 billion stock buyback plan. The announcement, coupled with a string of recent wins, has sent AMD shares soaring over 21% in the past month.AMD Stock Technical Breakout In ProgressChart created using Benzinga ProAMD has broken past resistance at around $115 and is charging toward its 200-day simple moving average (SMA) of $127.18. With the stock trading above its five ...

Financial Data and Key Metrics Changes - The company experienced strong new client organic flows of $400 million in Q1 2025, following $1.4 billion in Q4 2024, totaling $1.8 billion over the past two quarters [4] - Total Assets under Management (AUM) was $34.3 billion, with discretionary AUM at $22.7 billion, remaining flat year over year [5][8] - Revenue for the quarter was $31.4 million, an increase of $1.1 million or 3.7% year over year, primarily driven by market appreciation [8] - Reported net income for the quarter was approximately $3.9 million, translating to $0.26 per Class A share [10] - Total assets decreased from $194.4 million at the end of 2024 to approximately $159.9 million as of March 31, 2025 [11] Business Line Data and Key Metrics Changes - The company noted a robust new business pipeline, particularly in Global Value strategies, with significant potential for future growth [19] - The OCIO pipeline has slowed, but there is optimism for future flows as the company builds relationships with consultants [19][20] Market Data and Key Metrics Changes - The company is expanding its presence in Europe and Southeast Asia, with a focus on building relationships and establishing a proactive marketing strategy [36][39] - The firm is working on obtaining a European license to market its services more effectively [36] Company Strategy and Development Direction - The company plans to continue investing in talent and initiatives to enhance its presence in institutional and wealth markets [5] - A $12 million stock repurchase program was completed, indicating a commitment to returning capital to shareholders while investing in growth [6][28] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about securing more significant organic flows throughout 2025 despite short-term market volatility affecting results [5][21] - The company is navigating a period of hesitation in the search environment due to global macroeconomic uncertainties, but remains confident in long-term growth prospects [22][63] Other Important Information - A quarterly dividend of $0.20 per share was declared, to be paid on or about June 20, 2025 [7] - The company is focused on maintaining a healthy balance sheet to support ongoing capital returns and growth initiatives [6] Q&A Session Summary Question: Could you comment on the pipeline and what you're seeing for OCI as well as Global going forward? - Management noted that the nature of searches has changed, focusing on cultivating consultant relationships rather than traditional RFPs, and expressed confidence in the pipeline for Global Value strategies [15][16] Question: How are things in Europe and Singapore regarding AUM? - Management highlighted strong relationships in Europe and ongoing efforts to establish a proactive marketing presence, with a focus on regulatory compliance [34][36] Question: Can you share any color on potentially a new buyback? - Management indicated that they are seriously considering another buyback, emphasizing the importance of returning capital to shareholders while investing in growth [42][43] Question: How do you view the operating leverage and timing of revenue versus expenses? - Management acknowledged the challenges of achieving operating leverage in the current environment but expressed optimism about long-term growth and increasing margins [56][58] Question: Is the trend of international investors pulling capital from the U.S. a concern for Silvercrest? - Management stated that the majority of their assets are U.S.-based and expressed confidence in their global strategies to mitigate any potential impacts [65][67]

Core Viewpoint - U.S. corporate share buybacks have surged significantly, indicating a strong preference for repurchasing shares over dividend payments, with a total of $262 billion in buyback announcements since April 1 [2][9]. Group 1: Buyback Trends - April marked the strongest monthly pace for corporate share buybacks in years, acting as a stabilizing force in volatile markets [1][3]. - The trend of increasing buybacks following market corrections was observed during the Silicon Valley Bank crisis and the early stages of the Ukraine war [3]. - Companies are utilizing buybacks to boost earnings per share (EPS), signal confidence, and fend off activist investors, leading to a notable increase in share prices [9]. Group 2: Major Corporate Buybacks - Apple Inc. announced a staggering $100 billion buyback, reinforcing its long-standing practice of repurchasing shares [4]. - Alphabet Inc. followed with a $70 billion share repurchase, while Wells Fargo & Co. committed $40 billion to its own stock [5]. - Other notable buybacks include KLA Corp at $5 billion, Dick's Sporting Goods at $3 billion, and Shell PLC at $3.5 billion, showcasing a broad interest across various sectors [6]. Group 3: Sector-Specific Buybacks - The technology sector is particularly active, with Broadcom Inc. and Applied Materials Inc. each announcing $10 billion buyback plans [7]. - Consumer and industrial companies are also participating, with Graphic Packaging Holding Co., Ingersoll Rand Inc., and Cirrus Logic Inc. committing between $500 million and $1.5 billion, and MGM Resorts International announcing a $2 billion buyback [8].

Financial Data and Key Metrics Changes - The company reported a GAAP net loss of $10.6 million or negative $0.22 per basic common share for Q1 2025, which includes a provision for credit losses of $3.8 million or negative $0.08 per basic common share [23] - The book value at March 31 was $8.24 per common share, a decline of about $0.23 per share from Q4, primarily due to the GAAP net loss [24] - The aggregate CECL reserve at March 31 was approximately $180 million or $3.72 per common share, down from $201 million or $4.12 per common share in the previous quarter [24] Business Line Data and Key Metrics Changes - The total loan portfolio commitments ended the first quarter at $2 billion, with an outstanding principal balance of $1.9 billion and about $93 million of future fundings [14] - The loan portfolio yield for Q1 was 6.8%, up from 6.6% in the prior quarter, while excluding nonaccrual loans, the yield was 8.5% compared to 8.8% previously [15] - The company resolved two nonaccrual loans totaling about $97 million in UPB during the first quarter, reducing the risk-rated V loan count from seven at year-end to three remaining [10][11] Market Data and Key Metrics Changes - The commercial real estate market showed improved sentiment at the beginning of 2025, with tightening credit spreads and enhanced liquidity, although recent tariff announcements have introduced renewed uncertainty [8] - The company noted that commercial real estate is better positioned today compared to previous years, with a lower reset basis across most property types and markets [8] Company Strategy and Development Direction - The company plans to maintain higher liquidity, extend debt maturities, and engage in value-enhancing activities while navigating market volatility [12] - The company anticipates returning to new originations in the latter part of the year, which is expected to improve run rate profitability and earnings over time [13] Management's Comments on Operating Environment and Future Outlook - Management expressed cautious optimism regarding the commercial real estate market, noting that while there are headwinds, the debt markets remain open and functioning [11] - The management team emphasized the importance of resolving nonaccrual loans and maintaining liquidity to maximize value during uncertain times [21] Other Important Information - The company repurchased about 900,000 shares of common stock during the first quarter and has about 3.9 million shares remaining under its existing buyback authorization [12] - The company has three remaining nonaccrual loans rated five, with a total balance of about $223 million [25] Q&A Session Summary Question: How does the company balance stock buybacks versus originating new loans? - Management indicated that they are currently focused on preserving liquidity and have been active in stock buybacks, with plans to balance this against new originations later in the year [28][29] Question: What is the status of the risk-rated loans and potential downgrades? - Management noted that the majority of the portfolio is performing well, with no negative credit migration in the first quarter, and they are closely monitoring the risk-rated loans [30][32] Question: Can you clarify the realized losses and their timing? - Management confirmed that the $37 million write-off includes $22 million related to one resolution, and they expect to recognize these in distributable EPS [40][41] Question: What percentage of the portfolio matures in 2025? - Management clarified that a little over 20% of the portfolio has a final maturity in 2025, with loans maturing in 2026 and beyond as well [49][50] Question: What is the reserve on risk-rated four loans? - The reserve on risk-rated four loans is approximately $13.1 million, which relates to a balance of $174 million [53][54] Question: What is the status of the Miami office property? - Management indicated that the Miami office property is a high-quality Class A asset with potential, and they are actively reviewing resolution alternatives and leasing discussions [63][64]