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【华创医药】归创通桥-B(02190.HK)深度研究报告:神经和外周介入第一梯队,受益集采,布局海外
华创医药组公众平台· 2025-04-01 04:47
根据《证券期货投资者适当性管理办法》及配套指引,本资料仅面向华创证券客户中的金融机构专业投资者,请勿对本资料进行任何形式的转发。若您不是华创证券客户中的金融机构专业投资者,请勿订 阅、接收或使用本资料中的信息。 本资料难以设置访问权限,若给您造成不便,敬请谅解。感谢您的理解与配合。 摘要 神经+外周介入双引擎驱动,受益集采,布局海外。 公司在神经介入、外周介入产品线布局全面,截止2025/3/20,公司共战略布局66款产品及候选产 品,已在国内商业化产品共计47款。公司抓住集采机遇,推动产品放量,实现收入的强劲增长,2021-2024年收入CAGR达到131%,并在2024年实现扭 亏为盈,全年净利润为1亿元,截至2024年底,账上资金总额达到25亿元,充裕现金流为产品管线自研/并购、商业化拓展提供支持。2024年海外收入 2258万元,同比增长58.2%,海外拓展已初具规模,有望为公司贡献长期业绩增量。 神经 介入:渗透率、国产化率双 低赛道,公司以丰富产品组合拥抱集采 。 1)行业:渗透率、国产化率双低的高潜力赛道。 国内神介手术受众群体大,近些年手术渗透率快速提升,神经介入耗材市场规模同步快速增长,20 ...
【华创医药】归创通桥-B(02190.HK)深度研究报告:神经和外周介入第一梯队,受益集采,布局海外
华创医药组公众平台· 2025-04-01 04:47
根据《证券期货投资者适当性管理办法》及配套指引,本资料仅面向华创证券客户中的金融机构专业投资者,请勿对本资料进行任何形式的转发。若您不是华创证券客户中的金融机构专业投资者,请勿订 阅、接收或使用本资料中的信息。 本资料难以设置访问权限,若给您造成不便,敬请谅解。感谢您的理解与配合。 摘要 神经+外周介入双引擎驱动,受益集采,布局海外。 公司在神经介入、外周介入产品线布局全面,截止2025/3/20,公司共战略布局66款产品及候选产 品,已在国内商业化产品共计47款。公司抓住集采机遇,推动产品放量,实现收入的强劲增长,2021-2024年收入CAGR达到131%,并在2024年实现扭 亏为盈,全年净利润为1亿元,截至2024年底,账上资金总额达到25亿元,充裕现金流为产品管线自研/并购、商业化拓展提供支持。2024年海外收入 2258万元,同比增长58.2%,海外拓展已初具规模,有望为公司贡献长期业绩增量。 神经 介入:渗透率、国产化率双 低赛道,公司以丰富产品组合拥抱集采 。 1)行业:渗透率、国产化率双低的高潜力赛道。 国内神介手术受众群体大,近些年手术渗透率快速提升,神经介入耗材市场规模同步快速增长, 2 ...
2毛钱的仿制药暴雷,问题出在哪儿?
虎嗅APP· 2025-03-29 09:59
以下文章来源于凤凰网财经 ,作者风暴眼 凤凰网财经 . 你好,我们是凤凰网财经,全球华人都在看的财经公众号,传播最有价值的财经报道,你值得关注!欢 迎访问:http://finance.ifeng.com/ 本文来自微信公众号: 凤凰网财经 (ID:finance_ifeng) ,作者:玲子,原文标题:《2毛钱的仿制药暴 雷,最担心的事还是发生了》,题图来自:AI生成 2024年底,北方一家制药公司的办公室里,几位研发、采购人员围坐一圈,在稿纸上、白板上疾笔写下一 串串数字。3分钱/片的阿司匹林肠溶片、0.22元/支的间苯三酚注射液,按照理论成本,无论换多少种计算方 法,他们也算不出这个价格。此时,第十批集采的中标价刚刚出炉,整个医药圈都骚动起来。 "至少需要五六毛!"有人把笔一搁,最后一轮演算,成本价最多还是只能压到这里。研发主管郭青沉思片 刻,试图给出合理解释:"估计是为了打出品牌"。马上有人附和:"如果企业技术很厉害,应该有更好的方 式控制成本吧……" 郭青在仿制药研发领域摸爬滚打了七年,经手过50余个研发项目。他所在的公司曾参与集采竞标,有几款 产品顺利中标。通常,他会遇到两三毛钱的压价,觉得这在预期 ...
2毛钱的仿制药暴雷,最担心的事还是发生了
凤凰网财经· 2025-03-28 13:17
凤凰网《风暴眼》出品 文|玲子 2024 年底,北方一家制药公司的办公室里,几位研发、采购人员围坐一圈,在稿纸上、白板上疾笔写下一串串数字。 3 分钱 / 片的阿司匹林肠溶 片、 0.22 元 / 支的间苯三酚注射液,按照理论成本,无论换多少种计算方法,他们也算不出这个价格。此时,第十批集采的中标价刚刚出炉,整个 医药圈都骚动起来。 "至少需要五六毛!"有人把笔一搁,最后一轮演算,成本价最多还是只能压到这里。研发主管郭青沉思片刻,试图给出合理解释:"估计是为了打出 品牌"。马上有人附和:"如果企业技术很厉害,应该有更好的方式控制成本吧……" 郭青在仿制药研发领域摸爬滚打了七年,经手过 50 余个研发项目。他所在的公司曾参与集采竞标,有几款产品顺利中标。通常,他会遇到两三毛钱 的压价,觉得这在预期范围之内,规模效应带来的持续订单和利润,与暂时的让价相比,总是更有诱惑力的。但第十批集采的激烈厮杀,他却前所未 见。 而近期,就在第十批集采落地前夕,饱受争议的超低价中标药间苯三酚注射液忽然被曝出不符合要求,两家涉事药企遭同步重罚 —— 委托方四川海 梦智森生物制药有限公司(下称"海梦智森")与受托方太极集团四川太极制 ...
石四药集团(02005)发布年度业绩 股东应占溢利10.61亿港元 同比减少19.53% 拟派末期息每股0.095港元
智通财经网· 2025-03-28 04:17
Core Viewpoint - The company reported a decline in revenue and profit for the fiscal year ending December 31, 2024, with a focus on improving market accessibility and product approvals despite challenging market conditions [1][2]. Group 1: Financial Performance - The company's revenue for the year was HKD 57.73 billion, a decrease of 10.67% year-on-year [1]. - Shareholders' profit was HKD 10.61 billion, down 19.53% compared to the previous year [1]. - Basic earnings per share were HKD 0.3582, with a proposed final dividend of HKD 0.095 per share [1]. Group 2: Product Approvals and Market Access - The company successfully completed the market access for 44 generic names and 56 specifications, with significant approvals in various provinces [2]. - The company participated in over a thousand bidding activities, achieving notable success in national and regional procurement initiatives [2]. - The company has 162 products listed in the national medical insurance directory, with new products successfully entering the 2024 updated directory [2]. Group 3: Business Segments Performance - The infusion and ampoule water products maintained stable performance, with total sales volume reaching 2.036 billion bottles (bags), a year-on-year increase of 6.7% [3]. - Sales revenue for infusion products was HKD 37.35 billion, a decrease of 7.6% due to market demand and pricing pressures [3]. - The oral formulation segment saw significant growth, with sales revenue reaching approximately HKD 5.02 billion, up about 4.9% year-on-year [4]. Group 4: Raw Material Drug Segment - The raw material drug segment experienced a sales revenue decline of 11.7%, totaling approximately HKD 7.85 billion [4]. - Caffeine sales volume increased by about 44% to 5,478 tons, while sales of metronidazole decreased by 43% [4]. - The company anticipates a stabilization and recovery in the raw material drug business in the coming year [4].
不用伪装的戾气
猫笔刀· 2025-03-27 14:21
昨晚评论席互动的时候聊到了网络实名制,我说起点是2013年,很多读者没概念,我说具体一点,最重要的措施是2013年9月1日施 行的《 电话用户真 实身份信息登记规定 》。 在这之前普通人可以随意购买电话卡,不用绑定个人信息,这既意味着可以匿名电话,也意味着可以匿名上网,因为上网的前置基础是电 话卡。电话卡实名登记后,互联网上的所有行为,本质上都可以定位到具体的个人。 我读高中、大学那会,去网吧交钱就给开机,后来才有了必须登记身份证这一环节,也是为了互联网行为穿透到个人。不然你在网吧上网 乱讲话,到时候警察查过来网吧老板吃不了兜着走。 至于全面落实网络实名制还要再晚两年,到了2015年3月互联网所有平台账号都落实实名制,从那以后你想给别人的评论点个赞,都要验 证过手机号才行。 至于读者留言说就算有了实名制,很多网民还是浑身戾气。那是因为这些人知道谁能开盒他,有戾气也要憋着,至于网民和网民之间没有 开盒的威胁,人性的阴暗面根本不用装 …… 今天a股成交1.19万亿,量能比昨天少少反弹了一些,今天小微盘股的表现不佳,个股中位数-0.63%,正好把昨天的+0.63%又跌了回 去。今天涨最好的还是化学原料+2.9%,这 ...
中国中药利润大跌98.5%背后:过亿补税侵蚀业绩,合规漏洞凸显
Bei Jing Shang Bao· 2025-03-26 12:15
Core Viewpoint - China Traditional Chinese Medicine (CTCM) reported a significant decline in net profit by 98.5% for the fiscal year 2024, primarily due to over 100 million yuan in tax payments that severely impacted profitability and highlighted compliance management issues within the company [1][6][7]. Financial Performance - CTCM's revenue for 2024 was 16.51 billion yuan, a decrease of 8.9% year-on-year [4][5]. - The net profit for 2024 was only 20.77 million yuan, marking a drastic drop of 98.5% compared to the previous year [3][5]. - Gross profit fell to approximately 7.86 billion yuan, down 15.3% from 9.27 billion yuan in the previous year, resulting in a gross margin of 47.6%, a decline of 3.6 percentage points [5]. Business Segment Performance - The production and operation of traditional Chinese medicine materials saw a revenue decline of 25.3% [3]. - The Chinese herbal pieces segment experienced a revenue increase of 17.9%, reaching 3.31 billion yuan, although its gross margin was only 23.2% [5]. - The Chinese medicine formula granules segment, once a key revenue driver, saw a 23.5% drop in revenue to 6.97 billion yuan, with a gross margin decrease from 56.9% to 48.3% [5]. Tax Compliance Issues - CTCM acknowledged that the significant drop in net profit was influenced by tax payments totaling approximately 1.53 billion yuan for the years 2017 to 2023, with 1.02 billion yuan already paid [6][7]. - The tax payments are expected to reduce the net profit attributable to shareholders by about 129 million yuan [6]. Market and Strategic Challenges - The company faces intensified market competition and structural changes in demand, particularly due to the implementation of national centralized procurement policies [4][5]. - CTCM's R&D investment for 2024 was 596 million yuan, a decrease of 13.1% from the previous year, which may hinder its competitive position in the market [5]. Stock Performance and Privatization Attempts - CTCM's stock price has been under pressure, with a significant drop following failed privatization attempts by its controlling shareholder, China National Pharmaceutical Group [8][10]. - The stock price fell by 44.5% to 2.12 HKD after the privatization announcement failed, reflecting investor concerns about the company's future [8][10]. Regulatory Environment - The company is under increasing regulatory scrutiny, necessitating a stronger focus on compliance and quality assurance to regain market trust [7][11].
套现近亿元!眼科器械龙头遭减持
思宇MedTech· 2025-03-24 03:42
合作伙伴征集:2025全球手术机器人大会 报名:首届全球眼科大会 | 名额有限 报名:首届全球心血管大会 | 奖项申报 报名:首届全球骨科大会 | 奖项评选 近日, 爱博医疗(688050.SH) 发布公告,披露了 公司股东白莹通过大宗交易方式累计减持公司股份110 万股 ,占公司股份总数的0.58%,减持价格为87.58元/股, 金额为9633万元 。本次减持完成后,白莹及其 一致行动人合计持有公司股份1516.72万股,占公司股份总数的8.002%。 值得注意的是,白莹作为 公司的天使投资人 ,并未参与公司的日常管理,而 此次减持却发生在公司营收和净 利润连续7年双增长的"高光时刻" 。自登陆科创板以来,爱博医疗的净利润逐年增长,从2018年的2031万元 增长至2024年的3.87亿元,七年复合增长率(CAGR)达78%, 累计涨幅18倍 。这增长速度,连茅台(同 期CAGR 29%)看了都得连连称赞。 然而,尽管财务数据亮眼, 业绩一路高歌,但公司股价却像被按了暂停键 ,资本退潮迹象明显。这一现象背 后折射出眼科器械行业的深层变化,包括带量采购对利润的挤压、国产替代的激烈竞争,以及企业转型的压 力。 ...
开源证券晨会纪要-2025-03-14
KAIYUAN SECURITIES· 2025-03-13 23:45
Investment Rating - The report maintains a "Buy" rating for several companies, including Century Internet, Huayi Group, and 361 Degrees, indicating a positive outlook for their future performance [19][25][31]. Core Insights - The report highlights significant growth in capital expenditure for Century Internet, projecting a 101-141% increase in 2025, driven by strong demand in the AIDC sector [15]. - The AI and cloud computing sectors are experiencing increased investment from both domestic and international giants, which is expected to accelerate AI application deployment [16]. - The report emphasizes the robust growth potential in the AIDC cloud computing market, with recommendations for various companies across different segments [17]. - Huayi Group is expected to see a revenue increase of 19.4% in 2024, with a focus on expanding production capacity and optimizing customer structure [19]. - 361 Degrees anticipates breaking the 10 billion yuan revenue mark in 2024, with a strong emphasis on exploring new retail formats [25]. - The report notes that the toy market, particularly in the building block segment, is rapidly growing, with a projected increase in market size from 773.1 billion yuan in 2023 to 993.7 billion yuan by 2028 [32]. - Shandong Pharmaceutical Glass is positioned to benefit from the increasing demand for borosilicate glass, with projected net profits growing significantly over the next few years [36][37]. Summary by Sections Technology Sector - The report discusses the trading congestion indicators for the technology sector, suggesting that high trading volumes may indicate a risk of price corrections [3]. - Relative valuation metrics show that technology growth stocks are not at historical extremes but are also not particularly cheap, with TMT and robotics sectors at high percentiles [4][5]. Communication Sector - Century Internet's capital expenditure is expected to reach 100-120 billion yuan in 2025, reflecting a strong growth trajectory in the AIDC market [15]. - The demand for AIDC services is anticipated to accelerate, supported by significant contracts from major clients [15]. Consumer Goods Sector - Huayi Group's new factory efficiency is expected to impact Q4 earnings positively, with optimistic projections for Adidas orders [19]. - 361 Degrees is actively exploring new retail formats and anticipates a revenue increase of 19.6% in 2024 [25]. Toy Industry - The report highlights the rapid growth of the building block toy market, with a significant market share held by companies like Bluko, which is leveraging a strong IP portfolio [31][32]. Pharmaceutical Glass Industry - Shandong Pharmaceutical Glass is expected to see substantial growth in net profits due to the increasing adoption of borosilicate glass in the pharmaceutical sector [36][37].
刚刚,政府工作报告现场传来这些重磅消息!
证监会发布· 2025-03-05 04:07
今年发展主要预期目标 国内生产总值增长 中国政府网 www.gov.cn 国务院客户端 国务院 State Council App 今年赤字率拟按 4%左右安排。 国务院 国务院客户端 中国政府网 State Council App 拟发行超长期特别国债 1.3万亿元、比上年增 加3000亿元。 拟发行特别国债5000 亿元,支持国有大型商 业银行补充资本。 国务院客户端 国务院 State Council App 拟安排地方政府专项债 券4.4万亿元、比上年 增加5000亿元,重点 用于投资建设、土地收 储和收购存量商品房、 消化地方政府拖欠企业 账款等。 国务院客户端 报告 优化和创新结构性货 币政策工具,更大力 度促进楼市股市健康 发展,加大对科技创 新、绿色发展、提振 消费以及民营、小微 企业等的支持。 中国政府网 = 国务院各户端 State Council App 安排超长期特别 国债3000亿元 支持消费品以旧 换新。 国务院客户端 国务院 中国政府网 State Council App 建立未来产业投 入增长机制,培 育生物制造、量 子科技、具身智 能、6G等未来 产业。 中国政府网 ● 国务 ...