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天大元英进院士团队:开发兆级别人类基因组DNA合成和跨物种转移新技术
合成生物学与绿色生物制造· 2025-07-11 15:57
Core Viewpoint - Synthetic biology aims to "synthesize and design life," with significant advancements in genome synthesis and assembly, particularly in higher organisms, despite facing challenges related to repetitive sequences and cross-species DNA transfer [1][2]. Group 1: Technological Breakthroughs - Tianjin University's team achieved the first precise assembly and cross-species delivery of megabase-scale human DNA, marking a significant milestone in synthetic biology [2]. - The newly developed SynNICE technology enables the precise assembly of highly repetitive human genomic sequences in yeast and facilitates the efficient transfer of synthetic DNA into mouse embryos [3][5]. Group 2: Research Findings - The study successfully demonstrated de novo DNA methylation patterns in mouse embryos, indicating that the synthetic genome can be recognized and modified by the host cell environment [5][7]. - A hierarchical assembly strategy was employed to synthesize a 1.14 Mb region of the human Y chromosome, which is crucial for understanding male infertility [3][7]. Group 3: Implications for Disease Treatment - The research opens new avenues for treating chromosomal abnormalities and could lead to innovative therapeutic strategies for related diseases [7][9]. - The potential for using genetically modified pigs as organ donors for humans could be enhanced, addressing the global organ shortage issue by improving the longevity of transplanted organs [9][10]. Group 4: Future Prospects - The SynNICE technology platform is expected to facilitate large-scale genomic modifications, potentially transforming organ transplantation practices and enhancing the understanding of genetic diseases [11][12]. - The advancements in synthetic genome assembly and transfer techniques are anticipated to propel the field of synthetic biology forward, providing new models for studying epigenetic modifications and chromosomal disorders [10][11].
第十一届尼山世界文明论坛闭幕,多场平行论坛引关注
Xin Jing Bao· 2025-07-11 14:36
Group 1: Forum Overview - The 11th Nishan World Civilization Forum concluded in Qufu, Shandong, with over 560 participants engaging in discussions on "the relationship between civilizations and global modernization" through 38 activities including keynote speeches and high-level interviews [1][2] - The forum featured a financial culture forum for the first time, focusing on how traditional Chinese culture can empower modern financial development [2][3] Group 2: Financial Culture Forum - The financial culture forum attracted over 70 domestic and international guests, representing various industries and research fields, discussing moral norms and economic ethics embedded in traditional Chinese culture [2][3] - International guests shared experiences from countries like the USA, Germany, and Malaysia, while representatives from major Chinese financial institutions explored new practical paths [2] Group 3: Traditional Medicine and Cultural Exchange - The forum included a Traditional Chinese Medicine (TCM) cultural experience area, where international guests participated in various TCM services, highlighting the integration of Confucian culture and TCM [4][5] - The TCM cultural forum, established in 2021, serves as a platform for promoting TCM culture and its achievements, aligning with the theme of "TCM culture and modern civilization" [4][6] Group 4: Regional Development and Healthcare - Jining's local government emphasized the integration of Confucian philosophy and TCM principles, promoting high-quality healthcare development in line with the Healthy China strategy [5][6] - Jining has established itself as a regional medical hub, with all counties and districts providing comprehensive TCM services, and aims to contribute to national TCM development through ongoing reforms [6]
日债爆雷波及全球长债市场,美国30年期国债收益率一度逼近5%!
Sou Hu Cai Jing· 2025-07-11 14:24
Group 1 - The core issue of the "long bond crisis" is not just supply and demand but also the impact of currency basis swaps leading to a global bond market crash [2][5] - The Japanese long-term bonds and U.S. long-term bonds have shown unprecedented coupling, where a crisis in one country's bonds can trigger a crisis in others, indicating a high level of interconnectedness in the bond markets [12][9] - The global public debt is projected to reach a historical high of $102 trillion in 2024, up from $97 trillion in 2023, exacerbating the situation as developed countries reduce their purchases of long-term bonds due to aging populations [1] Group 2 - The recent sell-off in Japanese long-term bonds has led to a significant increase in yields, with the 30-year Japanese government bond yield rising from 2.85% to 3.10%, a 25 basis point increase [1] - The sell-off in Japanese bonds has caused a ripple effect, leading to increased yields in German and U.S. bonds, with the German 30-year bond yield rising from 3.1% to 3.21% and U.S. 30-year bonds exceeding 4.9% [1] - Historical patterns indicate that this is not the first occurrence of a "long bond crisis," as similar events were observed in April and May, highlighting the increasing sensitivity and deteriorating liquidity in long-term bond markets [8][6]
鑫慷嘉爆雷疑云:黄先生是谁?
经济观察报· 2025-07-11 14:12
那么,在鑫慷嘉事件中,这位关键人物"黄先生"到底是谁呢? 黄先生是否就是黄鑫? 真实的鑫慷嘉目前处于一种什么状况?2025年7月9日,记者来到深圳市龙岗区南湾街道宝岭社区 龙泉别墅8区K70栋,即深圳鑫慷嘉大数据服务有限公司(下称"深圳鑫慷嘉")的注册地试图一探 究竟。但在现场,记者并未发现有与鑫慷嘉相关的企业标识。记者经多方查询后得知,因"通过登 记的住所或者经营场所无法联系",深圳鑫慷嘉已于2月份被深圳市市场监督管理局龙岗监管局列 入经营异常名录。 对此,林大松向记者表示,运营鑫慷嘉的主体是贵州鑫慷嘉大数据服务有限公司(下称"贵州鑫慷 嘉")。出于推行所谓"四大战区"发展策略的需要,他们虽然亦分别在很多地方注册了一些公司, 但主要是为了广告宣传,并没有实质性的办公,深圳鑫慷嘉就属于这一情形。 值得注意的是,从参与创设到退出,黄鑫从来没有在贵州鑫慷 嘉担任具体管理职务。在贵州鑫慷嘉"主要人员"一栏中,亦没 有姓黄的人士。那么,被视为鑫慷嘉灵魂人物的"黄先生",究 竟是谁呢? 作者:邹永勤 封图:图虫创意 "加入鑫慷嘉,幸福千万家!"这句在近半年来十分火爆的洗脑式宣传语句,突然变得极具讽刺意 味,原因是作为宣 ...
鑫慷嘉爆雷疑云:黄先生是谁
Jing Ji Guan Cha Wang· 2025-07-11 13:50
Core Viewpoint - The "DGCX Xin Kang Jia Data" trading platform, known as "Xin Kang Jia," is facing severe allegations of financial misconduct, including withdrawal suspensions and platform crashes, leading to a significant loss of trust among its 1.8 million members and over 10 billion yuan involved [1][10]. Company Structure and Operations - Xin Kang Jia operates under the entity "Guizhou Xin Kang Jia Data Service Co., Ltd.," which was established in March 2021 by three individuals, including Huang Xin, who later transferred their shares to Liu Hailiang in April 2024 [2][3]. - The platform's rapid growth is attributed to its promotion of a "state-owned enterprise" identity and the use of digital currency for transactions, employing a "pyramid scheme" model to attract investments through member recruitment [4][5]. Allegations and Legal Issues - The platform has been linked to illegal fundraising activities, with regulatory bodies in various provinces issuing warnings about its operations, labeling it as a typical pyramid scheme [10][11]. - The name "DGCX" in the platform's title falsely implies a connection to the Dubai Gold and Commodities Exchange, which has not authorized any operations in China [9][10]. Current Status and Future Prospects - Following the withdrawal of key shareholders and the announcement of a company dissolution, the platform has been unable to facilitate withdrawals since June 26, 2023, leading to a crisis among its members [10][11]. - Despite the turmoil, some members remain hopeful for a recovery, with plans to potentially shift operations to Hong Kong, where a new company has been registered [7][8].
无法提现!年化365%的平台突然崩盘!创始人彻底失联,投资者称“我们是来填坑的”
21世纪经济报道· 2025-07-11 12:39
Core Viewpoint - The article discusses the collapse of the digital financial platform "DGCX Xin Kang Jia," which promised a daily return of 1% but ultimately left investors unable to withdraw their funds, highlighting the deceptive practices and risks associated with such platforms [1][3][12]. Summary by Sections Platform Operations and Collapse - "DGCX Xin Kang Jia" operated under the guise of a virtual currency investment platform, claiming to connect with the Dubai Gold and Commodity Exchange (DGCX) and promising an annualized return of 365%, significantly higher than traditional bank products [12][14]. - Despite multiple warnings from regulatory bodies starting in January 2025, the platform continued to attract investments until its collapse in June 2025 [3][17]. Investor Experiences - Many investors, like a mother from Shanxi, were lured into investing without understanding the risks, often influenced by friends or family [4][21]. - Some early investors managed to withdraw their funds before the collapse, indicating a predatory structure where later investors were essentially funding the returns of earlier ones [5][15]. Deceptive Practices - The platform employed a multi-level marketing structure, incentivizing users to recruit new members, which is characteristic of Ponzi schemes [15][23]. - The platform's operations included misleading claims about the legitimacy of its USDT transactions, which were used to obscure the true nature of the investment and evade regulatory scrutiny [14][15]. Regulatory Warnings and Public Response - Regulatory agencies issued multiple warnings about the platform's illegal activities, but these did not deter the influx of investments, reflecting a general lack of due diligence among investors [17][20]. - The article emphasizes the importance of recognizing the signs of fraudulent investment schemes, such as promises of high returns and reliance on recruitment for returns [21].
泰山保险自主开展线下金融教育宣传活动
Qi Lu Wan Bao· 2025-07-11 10:44
为进一步推进金融教育宣传常态化,积极承担消费者权益保护主体责任,帮助社会公众增强维护自身合法权益的意识和能力,5月至6月间,泰山保险多家分 公司积极组织开展线下金融教育宣传活动,推动金融知识惠及更多消费者。 天津分公司∣聚焦村镇老年群体金融教育 5月25日,天津综合业务一部团队联合宁河区苗庄镇镇政府和当地派出所,开展村镇老年人金融教育宣传活动。活动现场针对老年人易受骗的特点,重点讲 解了养老诈骗、非法代理骗局、高息非法集资等常见骗局的手段、特点,同时,发放宣传手册,帮助老年人巩固金融知识。活动现场参与群众超100人次, 发放宣传材料100余份,解答咨询50余例,切实解决老年人"信息滞后"难题。通过本次下沉服务,填补了偏远地区金融教育空白。 山西分公司∣金融护航爱心护考 高考期间,山西分公司及其各分支机构在考点附近设置爱心护考服务点,为考生和家长提供扇子、矿泉水等物资,设置休息区域,供家长休息等待,并利用 休息期间向家长发放宣传资料,主动普及金融知识。针对家长们关心的保险理赔、个人信息保护、金融诈骗等内容,进行了详细解答,结合案例,普及防范 金融诈骗技巧,有效帮助家长们了解保险知识,提高风险防范意识。此次活动将 ...
四川邛崃山首次发现“仙女的拖鞋”野生种群 将改写学术界传统“认知”
Huan Qiu Wang Zi Xun· 2025-07-11 09:48
来源:环球网 此次在邛崃山系(成都区域)发现雅致杓兰居群,是物种分布记录的重大突破。此前雅致杓兰国内仅在 滇西北和藏南有记录,邛崃山发现将其分布区向东扩展了数百公里,表明该物种可能具有比已知更强的 环境适应性。同时,邛崃山作为横断山脉北端的重要山系,该物种的发现,也证明了邛崃山可能会成为 高山植物应对气候变化的"避难所"。雅致杓兰目前已被世界自然保护联盟(IUCN)物种红色名录收 录,其受威胁等级评定为"濒危"(EN)。在我国,它被列为国家二级重点保护野生植物,受到法律严 格保护。 那么该物种为何如此珍稀濒危?成都市保护地和野保中心相关负责人表示,杓兰属植物普遍面临生存危 机,绝大多数种类都处于受威胁状态。其中,杓兰种子细小且胚乳退化(种子自身储存的营养很少), 在自然条件下几乎无法独立萌发,必须依赖与特定微生物的共生关系才能完成其生活史。 此外,雅致杓兰分布海拔狭窄,且需要腐殖质丰富的特定生境。这种狭窄的海拔范围使其对气候变化极 为敏感。因此,像邛崃山这样潜在的气候避难所对其长期生存至关重要。"2024年对同属濒危种福氏杓 兰的保护遗传学研究发现,该物种存在严重的遗传瓶颈事件,遗传多样性非常低,种群结构复杂 ...
太保产险山东分公司积极开展7·8全国保险公众宣传日活动
Qi Lu Wan Bao· 2025-07-11 07:29
Core Viewpoint - The company actively engages in public insurance education and awareness activities to enhance the image of the insurance industry and fulfill its social responsibilities, particularly during the "7.8 National Insurance Publicity Day" [1][2][8] Group 1: Public Engagement Activities - The company organized a series of events including a financial knowledge fair and a walking event, where they set up a "Financial Energy Station" to educate the public on topics such as claims guidance and fraud prevention [2] - Interactive games and quizzes were utilized to make learning about insurance enjoyable for citizens, promoting the concepts of love and responsibility in insurance [2] - The company performed a program titled "Three Sentences of Financial Knowledge" to entertain and educate the audience, receiving positive feedback from attendees [2] Group 2: Community Outreach - The company initiated the "Five Entering" campaign, where managers and volunteers visited community centers to disseminate insurance knowledge, focusing on the "three appropriateness" principle and warning against fraudulent practices [4] - Educational efforts included discussions on insurance contracts, rational investment, and financial crime prevention, aimed at enhancing consumer understanding and interaction [4] - The company also engaged with local businesses to promote fire safety and risk management, gathering insights on consumer needs and experiences [4] Group 3: Grassroots Financial Education - The company is committed to building a "grid-based" financial education system, conducting outreach activities that are closer to the community and addressing local needs [5] - Financial education teams visited rural markets to provide financial knowledge, assist with inquiries, and raise awareness about financial fraud risks [5] - The focus is on creating a more effective and impactful educational outreach that resonates with the community [5][6] Group 4: Future Commitment - The company plans to continue enhancing insurance literacy among the public, ensuring that more people understand and trust insurance services, thereby supporting their quality of life [8]