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X @The Economist
The Economist· 2025-07-11 23:40
Company Overview - The world's biggest toymaker's strategies for staying creative and profitable are explored [1] Industry Insights - The "Boss Class" podcast discusses the toymaker's approach [1]
Makary Reveals What’s Broken Inside the FDA
Bloomberg Television· 2025-07-11 23:06
Opioid Crisis & Regulatory Reform - FDA 承认在阿片类药物监管方面存在失败,并对由此造成的阿片类药物滥用危机表示担忧 [1] - FDA 计划审查 OxyContin 等药物的标签,确保其准确性并与科学依据相符 [2] - FDA 致力于移除咨询委员会中所有可能的行业成员,以维护科学流程的公正性 [3] - FDA 将加强对已批准药物的上市后监测,利用大数据识别潜在的安全信号 [3][4] - FDA 将取消阻止安全流行病学研究的权限,确保安全团队能够自由工作,避免利益冲突 [5] Drug Approval & Transparency - FDA 正在进行全国范围的意见征集,听取 CEO 们对改进 FDA 的想法 [13] - FDA 致力于提高透明度,公开决策信函,使药品开发商能够了解药品未被批准的原因 [14][17] - FDA 正在利用 AI 技术来组织和分析大量的申请文件,以实现现代化 [18] - FDA 推出了一项试点计划,对于符合美国国家优先事项的药物,提供优先审查凭证,将决策时间缩短至 1-2 个月 [20] - FDA 员工数量自 2007 年以来翻了一番,存在大量冗余,需要进行整合 [21] Investment & Deregulation - FDA 采取放松监管的态度,旨在加快审批流程,同时不降低安全标准 [23] - FDA 将与行业保持沟通,确定哪些产品符合国家优先事项,例如满足未满足的公共卫生需求、实现国内生产以及提高药品的可负担性 [24] - FDA 计划对承诺在 OECD 国家和美国之间实现药品价格均等化的公司发放国家优先审查凭证,以激励市场中的良好行为 [25]
Clean Start: Investing in eco-friendly sea walls
CNBC Television· 2025-07-11 21:23
Environmental Impact & Sustainability - Traditional seawalls are environmentally unfriendly due to chemical leaching, prompting the need for eco-friendly alternatives [1] - Kind Designs' seawalls mimic mangroves and marine habitats, creating artificial reefs that sequester approximately 40 pounds (18.14 kg) of carbon per panel annually, equivalent to a tree's carbon sequestration [1][4] - The company utilizes a rapid setting cement with a 32% lower CO2 footprint compared to traditional Portland cement, and its materials are non-metallic and non-toxic [3] - Living seawalls eliminate the need for expensive offsets often required by permitting agencies to mitigate the environmental damage caused by traditional seawalls [6] Product Features & Benefits - Kind Designs' 3D-printed seawalls protect coastal communities from rising tides and function like reefs, dissipating 47% of wave energy and improving water quality [2] - The design attracts native species and creates habitats, transforming the infrastructure into living artificial reefs that promote bioalcification [4] - Installation is faster, with a curing time of 3 days compared to a month for legacy seawalls, and any contractor can install them [2][7] Financials & Investment - Kind Designs has secured $11.5 million in total VC funding from investors including Florida Opportunity Fund, Anthroposine Ventures, Go Ventures, Overlay Capital, and Mark Cuban Companies [5] - The panels cost approximately $30 per square foot, comparable to traditional panels, with additional cost savings due to the elimination of offset requirements [5]
NOW: Trump, First Lady meeting with first responders, families in Texas
MSNBC· 2025-07-11 21:05
Disaster Overview & Impact - The community and nation are deeply affected by the significant loss of life along the Guadalupe River [1] - Over 160 people in Kerr County are still missing [5] - A memorial has been set up along the Guadalupe River to honor the victims [3][4][5] Accountability & Preventability - Officials were warned about the potential for a severe flooding event as early as October [2] - There is growing evidence that officials could have and should have done more to prevent the tragedy [8] - A special legislative session is scheduled for July 21st to address these issues [8] - The Lieutenant Governor and Speaker of the House in Texas will conduct joint investigations to understand the facts leading to the event [9] - Local officials requested a siren system multiple times, but the state denied the request [10][11] Emergency Response & FEMA Involvement - FEMA instituted a policy requiring all expenses over $100,000 to be approved directly by the Homeland Security Secretary, raising questions about potential delays in emergency relief [22][23] - Kerr County did not alert cell phones as the flooding began, and there were delays in sending out code red alerts [24][25] - The FEMA administrator has not been visible or involved in the disaster response, raising questions about FEMA's autonomy [17][18][20]
Texas 'deserves transparency!' Noem, Trump facing backlash over FEMA response
MSNBC· 2025-07-11 16:56
Today, multiple Democratic lawmakers, including some from Texas, are formally demanding answers from the administration about the impact of budget cuts and DHS policies on the government's ability to respond to the devastating floods. Texas Democratic Congressman Greg Quesar is one of them, chair of the Congressional Progressive Caucus, and he joins me now. Congressman, it's good to have you on the program again.What are the specific concerns both that you've heard raised but also the questions you want ans ...
X @TechCrunch
TechCrunch· 2025-07-11 16:40
Security Vulnerability - CISA confirms hackers are actively exploiting critical 'Citrix Bleed 2' bug [1]
A Maverick's Blueprint: Connecting Confidence and Goals | Alexia Hoffman | TEDxBrown County Schools
TEDx Talks· 2025-07-11 16:38
Goal Setting & Achievement - The speaker initially aimed to sell $100,000 in real estate, highlighting the importance of setting goals [1][11] - The speaker emphasizes identifying "joy trends" to understand one's true "why" behind goals, suggesting that perceived reasons may differ from actual passions [2][5] - The speaker advises setting a 5-10 year goal aligned with an ideal life, rather than pursuing goals based on external expectations [8][10] Personal Fulfillment & Authenticity - The speaker advocates for vulnerability and authenticity as essential for fulfillment, citing examples of public figures who shared their stories [14][15][16] - The speaker highlights the importance of aligning actions with one's true self for achieving fulfillment [17] Environment & Community - The speaker stresses the significant impact of one's environment and community on mindset, goals, and available resources [17][18] - The speaker shares a personal experience where sharing a goal with supportive coworkers led to encouragement and bigger thinking [19][20] Taking Action & Overcoming Fear - The speaker encourages taking bold action towards one's vision, even without feeling fully prepared [21] - The speaker shares the experience of opening a coffee shop with limited experience, emphasizing the value of real-life learning [21][22][24][25] - The speaker encourages listeners to begin working towards their goals without waiting for permission or feeling completely ready [26]
The power of genuine communication for meaningful connections | Hicham Jadaoun | TEDxLAU Byblos
TEDx Talks· 2025-07-11 16:28
Communication Skills Development - Communication skills can be improved like any other skill, regardless of innate talent [5] - Honesty and transparency enhance credibility in communication [9] - Continuous improvement is crucial, adapting to individual needs without altering one's core identity [10] - Personalizing communication by adding a unique touch is important [12] Authenticity and Uniqueness - Maintaining authenticity is as important as excelling in communication [6] - Over-reliance on AI can risk losing one's identity and unique self [7] - Embracing judgment and vulnerability is important for personal growth [13] - Genuineness, honesty, and vulnerability are key to impactful communication [13] Practical Tips for Improvement - Crafting a message and practicing it is a starting point [8] - Consistency in voice and attitude is essential; avoid pretense [9] - Every conversation is an opportunity for growth and learning [12] - Find your true self and share it with the world [13][14]
The Rise of the Digital Economy: Career Paths of the Future | Fares Antoun | TEDxLAU Byblos
TEDx Talks· 2025-07-11 16:13
Technology & Future Trends - The pace of change is exponential, requiring proactive shaping of the future rather than passive waiting [1] - Technology is evolving faster than our systems and minds, leading to significant changes in the next 10 years, potentially equivalent to the last 100 years [3] - The focus is shifting from job titles to skills, adaptability, and purpose, emphasizing problem-solving and life design [4] - Emerging platforms are expanding to protect emotional values beyond financial assets [7] Finance & Money - Money is evolving to be intelligent, contextual, connected, customized, and risk-aware, with smart wallets automating savings and investments [6] - Money is transitioning from a physical form to a cloud-based, intelligent, and interactive form, humanizing finance [7] - Over 70% of Gen Z and millennials prefer digital-first platforms powered by AI, quantum computing, blockchain, decentralized financing, and programmable currencies [8] AI & Human Role - AI will create 170 million jobs while replacing 92 million jobs over the next 5 years, according to the World Economic Forum [10] - The emphasis should be on humans being elevated by machines, leveraging empathy, critical thinking, and imagination [9] - The focus should be on how we choose to use AI to build a flexible, meaningful, and inclusive world [9][10] Meaning Economy - People are seeking alignment, values, identity, and purpose beyond paychecks, indicating a shift towards a meaning economy [8] - Profit and purpose are becoming partners, highlighting the importance of values in the modern economy [9]
CDW, Asato Boost Business Observability With AI-Driven IT Intelligence
ZACKS· 2025-07-11 14:56
Core Insights - CDW Corporation has partnered with Asato Corporation to provide AI-powered IT asset intelligence, addressing the complexities of modern IT infrastructures for a wide range of customers, from large enterprises to SMBs [1][9] - The collaboration aims to simplify IT operations, reduce costs, and enhance decision-making through Asato's AI-native business observability platform [2][3] Group 1: Partnership and Platform Benefits - The integration of Asato's platform into CDW's solutions enhances both companies' capabilities, allowing organizations to streamline IT operations and make smarter technology investments [3] - Asato's platform has shown measurable results in pilot deployments, including improved IT asset visibility, reduced technology waste, and enhanced financial planning [4][9] - The partnership provides a direct way for organizations to reduce IT bottlenecks and maximize asset utilization through AI-driven decision-making [5] Group 2: Customer Focus and Market Trends - CDW emphasizes tailored solutions for clients with diverse technology needs, ensuring effective and cost-conscious solutions amid macroeconomic uncertainties [6][8] - A notable project involved migrating a commercial truck manufacturer's HR systems to a cloud-hosted environment, generating over $1 million in professional services fees [7] - Despite cautious spending due to global uncertainties, customers remain focused on mission-critical projects, with CDW assisting in optimizing expenditures and planning [7][8]