Core Viewpoint - The approval of the drug "Mairuisheng" (Injectable Agrelin α) by the National Medical Products Administration marks a significant milestone for the company, being its first innovative drug to be launched and the first G-CSF drug in China developed using albumin fusion technology [2][3]. Drug Information - Drug Name: Injectable Agrelin α - Dosage Form: Injection - Specification: 20mg/vial - Indication: For adult patients with non-myeloid malignancies undergoing chemotherapy that may cause febrile neutropenia, to reduce the incidence of infections associated with febrile neutropenia [2][3]. Clinical Trial Results - In Phase III clinical trials, the incidence of grade 4 neutropenia during the first cycle of chemotherapy was slightly lower in the 8MW0511 group compared to the control group, and significantly lower in subsequent cycles [4]. Market Demand and Growth - The demand for long-acting G-CSF drugs in China is substantial, with the market expected to reach CNY 10.27 billion by 2025 and CNY 13.54 billion by 2030, indicating a positive market outlook [6]. - Over 50% of new cancer cases globally require chemotherapy, with the number of patients needing the first course of chemotherapy projected to increase from 9.8 million in 2018 to 15 million by 2040, a growth of 53% [5]. Impact on the Company - The launch of 8MW0511 is expected to enhance the company's revenue scale and improve its profitability and core competitiveness, providing a new treatment option for clinical experts and better clinical benefits for patients undergoing chemotherapy [6].

5月29日晚间，特宝生物（688278.SH，股价80.86元，市值328.94亿元）公告称，国家药品监督管理局 官方网站公示，公司申报的怡培生长激素注射液（商品名：益佩生）获批上市。 公告显示，益佩生是一款长效生长激素，可实现每周给药一次，适用于治疗3岁及以上儿童的生长激素 缺乏症所致的生长缓慢。 值得注意的是，在益佩生所处的长效生长激素赛道，长春高新旗下子公司金赛药业此前一直是市场上唯 一一家长效生长激素生产销售方。此次益佩生的获批上市，将打破金赛药业长达十年的垄断格局。 首个挑战者出现，长效生长激素市场迎变局 根据民生证券发布的研报，生长激素临床应用主要为治疗矮小症。目前，我国矮小症患者接受正规治疗 比例较低。根据第七次人口普查数据，按我国需要治疗的4至15岁人群基数及约3%的患病率计算，现存 矮小症发病人数约640万。 此次获批上市的益佩生，是特宝生物自主研发的一款采用40kD Y型分支聚乙二醇进行单分子修饰的长 效生长激素。其核心技术在于通过优化选择非N-末端位点为主的修饰组分，提高生物学比活性，延长 半衰期，从而在保证疗效的同时，降低给药剂量，获得更佳的长期药物安全性。 民生证券称，此前，金赛药业 ...

Core Viewpoint - The article emphasizes the commitment of SPD Bank Chongqing Branch to implement consumer protection policies as a core mission, actively exploring the construction of a long-term collaborative mechanism for financial education [1] Group 1: Financial Education Initiatives - SPD Bank Chongqing has established a collaborative public welfare brand called "Red Partner" in partnership with community service platforms, regularly dispatching financial educators and setting up knowledge promotion points to provide ongoing consultation services [2] - The bank focuses on hot issues such as illegal fundraising and fraud prevention, using case studies and interactive Q&A to enhance risk awareness among the public [2] - In 2023, the bank has conducted 30 activities, reaching over 5,000 people, and has received multiple commendations from the district financial office and community streets [4] Group 2: Targeted Outreach Programs - The bank has tailored its financial education content to meet the needs of different groups, such as labor workers focusing on fraud prevention and elderly individuals emphasizing investment risk warnings [4] - Specific initiatives include the "Financial Knowledge into Construction Sites" program, which provides practical knowledge on safe use of salary cards and fraud prevention during lunch breaks for new citizens like construction workers and delivery riders [2][4] - The bank also conducts quarterly promotions of the deposit insurance system, using simple language to explain policies to key demographics, including the elderly and new citizens [2]

转自：北京日报客户端 生态综合补偿是推动生态保护与治理、协调区域之间生态经济利益、推动各方保护生态环境的有效手 段。党的二十届三中全会《决定》指出：要"推进生态综合补偿，健全横向生态保护补偿机制，统筹推 进生态环境损害赔偿。"进一步推进生态文明建设，要持续健全生态综合补偿机制，激发优质生态区域 特别是国家重点生态功能区的"生态转换动力"，推动生态补偿由原来的区域内部省份之间、省份内城市 间以及中央政府对地方政府间"碎片化"的生态补偿机制，向中央政府以及全流域各地方政府共同参与的 综合生态补偿转变。 让高颜值的"绿水青山"转化为高价值的"金山银山" 当前，亟须通过进一步强化生态保护补偿长效机制建设，让高颜值的"绿水青山"转化为高价值的"金山 银山"。 以市场作为生态产品与保护付出之间的桥梁，能够有效调动各方参与生态保护的积极性，是对政府补偿 的有效补充。一方面，应充分发挥市场机制作用，做好生态产品价值实现与生态保护补偿制度的有效衔 接，鼓励社会力量以及地方政府按照市场规则购买生态产品和服务，通过激发保护区域的土地资源、劳 动力、资本和自然景观等要素的活力，提升生态产品价值转化能力。另一方面，拓宽生态保护补偿资金 ...

截至5月21日，专项行动的工作平台共汇集各地区各部门问题线索6232条，督促办理5246条。整治的问 题涉案金额3.35亿元，为企业挽回损失9881.35万元。 目前，司法部正在研究制定《行政执法行为规范》，厘清行政执法人员权力边界和行为边界，明确行政 执法人员禁止性行为和纪律要求，有效解决实践中出现的执法人员滥用职权、徇私枉法和粗暴执法等问 题。此外，司法部正在研究制定行政执法人员管理办法，健全执法人员准入和退出机制，坚决杜绝不具 备资格的人执法。 整治涉企乱收费，杜绝违规收费政策"带病"出台 当前部分领域的乱收费问题仍然存在，一些单位凭借优势地位违规收费屡禁不止，部分电子政务平台隐 性收费问题也比较突出，企业对此反映比较强烈。对此，市场监管总局市场稽查专员嵇小灵表示，今年 将坚持长短结合、标本兼治，从四个方面深化整治。 针对粗暴执法、任性执法和机械执法等问题，强化执法人员管理 司法部副部长胡卫列表示，这次专项行动目标明确，就是聚焦企业反映强烈的突出问题，精准监督，动 真碰硬，加大纠治力度，推进严格规范公正文明执法，促进行政执法机关、执法人员依法履职，该严则 严，当宽则宽，切实维护企业的合法权益，持续优化营 ...

同时，加大相关制度的落实力度。在规范行政执法行为方面，国家已经陆续出台过相关的制度，包括行 政执法公示制度、执法全过程记录制度和重大执法决定法制审核制度，这些制度对执法程序都作了严格 的规范。在健全行政裁量权基准制度方面，以及罚款的设定和实施方面出台了相关规定，对行政执法权 力的边界、范围、幅度都作了严格的规范和限制。"要通过强化执法监督，推动这些好的制度在实践中 得到不折不扣地执行，长效化地遏制执法乱象。"刘波表示。 在这次专项行动中，各地方、各部门在集中纠治执法突出问题上进行了积极探索，形成了一些好的做法 和经验，有的已上升为长效制度机制。在健全完善制度机制方面，将加快制定出台行政执法监督条例。 据介绍，目前已经完成了向社会公开征求意见，收集到不少好的意见和建议，下一步会抓紧推进出台。 针对执法突出问题制定具体的规则。涉企行政执法专项行动重点纠治的四类问题，具有反复性、复杂 性、顽固性，必须通过建立制度规范，从根本上加以解决。特别是随着新业态的出现，由于企业的生 产、经营、运输、销售这些环节会涉及不同地方，行政检查和行政处罚也会涉及异地执行的问题。前段 时间出台的国务院办公厅关于严格规范涉企行政检查的意见 ...

诚志股份有限公司投资者关系活动记录表 3、问董秘:公司研发人员有多少，其中研究生、博士生所占 比例是多少？公司发展离不开高端人才，薪酬分配能不能向一线 人才倾斜，不要十多个高管就分走了总薪酬的三分之一，公司那 么多概念，谁便一项搞得好，都不是现在的业绩。 证券代码： 000990 证券简称：诚志股份 编号：2025-002 | 投资者关系活动 | □特定对象调研 □ 分析师会议 | | --- | --- | | 类别 | 媒体采访 业绩说明会 □ √ | | | 路演活动 □ 新闻发布会 □ | | | □ 现场参观 | | | □ 其他 （请文字说明其他活动内容） | | 参与单位名称及 | 投资者网上提问 | | 人员姓名 | | | 时间 | 2025 年 5 月 21 日 (周三) 下午 14:30~17:00 | | 地点 | 公司通过全景网"投资者关系互动平台"（https://ir.p5w.net） | | | 采用网络远程的方式召开业绩说明会 | | 上市公司接待人 | 1、公司董事、总裁韦俊民 | | 员姓名 | 2、公司副总裁、董秘左皓 | | | 投资者提出的问题及公司回复情况 | | ...

Core Viewpoint - The company is enhancing its international check-in services to meet the growing and diverse demands of travelers during the busy season, aiming for a "zero time difference" quality service standard [1][5]. Group 1: Service Improvement Initiatives - The company is restructuring its international check-in service standards to synchronize service response speed with international timeliness standards [1]. - A three-dimensional training system has been established, combining theory, practical exercises, and reviews to prepare staff for unexpected situations during international flight operations [2]. - A standardized response process has been implemented, ensuring that check-in staff can effectively manage emergencies with a response time of 1 minute, resolution in 3 minutes, and closure in 5 minutes [2]. Group 2: Training and Development - Specialized training has been organized for new routes, focusing on visa validity calculations and operational guidelines for international flights [2]. - A comprehensive training program has been introduced, including bilingual communication, service skills, and etiquette, to enhance the service quality of check-in staff [3]. - The company is selecting key personnel to learn from advanced practices at other airports, ensuring continuous improvement in service delivery [2][3]. Group 3: Collaboration and Communication - The international check-in team has established a "policy direct communication group" with border inspection, customs, and relevant airlines to improve coordination and response capabilities during emergencies [3]. - The company is implementing a "first inquiry responsibility system" and a "5-minute response mechanism" to ensure timely resolution of passenger issues, thereby enhancing overall customer satisfaction [3]. Group 4: Long-term Service Strategy - The company plans to establish a long-term empowerment mechanism for international service operations, including regular retraining and case-sharing sessions to maintain high service standards [5].

圣兆药物 20250520 摘要 • 圣兆药物拥有 26 个在研管线，覆盖恶性肿瘤、精神分裂症等适应症，业 务模式以委托生产加自主生产为主，依托 MAH 制度，与吉林敖东、海正 药业和澳亚生物合作，其中盐酸多柔比星脂质体已获批上市并在集采中中 标。 • 公司核心技术团队由 90 多名研发人员组成，硕博比例高达 75%，包括多 位曾担任 CDE 新药审评专家的核心骨干，具备创新制剂领域丰富的产业化 经验，是国内创新制剂领域技术实力最强的团队之一。 • 复杂注射剂研发难度大，涉及工艺、原料药和质量控制等多个环节，但市 场规模巨大，如布比卡因 V0 等产品国内销售额均超 50 亿人民币，且具有 较高的技术壁垒和较快的临床周期，为企业带来高利润空间。 • 圣兆药物在复杂注射剂领域已申报并获批 8 个产品，其中 2 个已获批，6 个正在审评中，预计 2026 年左右获批，突破国外产业化技术壁垒，实现 线性放大连续化生产工艺，并拥有全球最大单批次产能，已授权 99 项发 明专利。 Q&A 圣兆药物的业务模式和技术平台有哪些特点？ 圣兆药物是一家专注于长效缓释和靶向制剂产品研发与产业化的医药企业。公 司成立于 2011 年 ...

Core Points - The newly revised "Regulations on Strictly Practicing Frugality and Opposing Waste by Party and Government Organs" aims to address the issue of extravagance within government agencies, emphasizing practical measures and clear guidelines to curb wasteful practices [1][2] - The regulations specifically target "hidden waste" and impose strict constraints on seemingly minor issues, such as prohibiting high-end meals and luxury configurations for official vehicles, thereby closing loopholes in daily operations [2][3] - The regulations are designed to combat formalism and bureaucratism, which are seen as significant challenges to governance, by halting unnecessary projects that waste public resources and financial assets [3][5] Implementation and Oversight - Effective implementation of the new regulations requires rigorous internal supervision, with government agencies expected to align their practices with the new rules and conduct thorough audits of expenditures related to public funds [5][6] - There is an emphasis on public involvement in monitoring compliance, with mechanisms in place for accountability and penalties for officials responsible for significant waste [6] - The ultimate goal of these regulations is to ensure that government savings translate into improved living standards for citizens, directing funds towards essential services such as education, healthcare, and rural revitalization [6]