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Segmented Configuration: Booting the Processing System (PS) First
AMD· 2025-06-23 12:31
Welcome to the Segmented Configuration: Booting the PS First tech module. Here is the agenda for this tech module. We will focus on the need for faster boot processes.Introducing the segmented configuration flow for enabling accelerated boot time. Describing how segmented configuration works. Describing how reconfiguring the programmable logic works in the segmented configuration flow.As technology advances, the pace of development and deployment has become a critical area of focus. Modern computing systems ...
Candel Therapeutics Appoints Charles Schoch as Chief Financial Officer
Globenewswire· 2025-06-23 12:05
Core Viewpoint - Candel Therapeutics has appointed Charles Schoch as the permanent Chief Financial Officer after his successful tenure as interim CFO, demonstrating strong financial leadership and guiding the company through significant operational and financial milestones [1][2]. Company Leadership - Charles Schoch has been with Candel since November 2021, serving in various financial roles, including VP of Finance and Corporate Controller, before becoming interim CFO in January 2024 [2][3]. - Under Schoch's leadership, the company raised approximately $86 million following positive phase 3 clinical trial results for CAN-2409 in localized prostate cancer [2]. Financial Management - Schoch has established strong investment banking relationships and has effectively managed capital during a complex market environment, supporting Candel's strategic priorities [2][4]. - The finance function under Schoch oversees financial close processes, internal controls, SEC reporting, financial planning, procurement, payroll, and treasury operations [2]. Clinical Development - Candel is focused on developing multimodal biological immunotherapies, with CAN-2409 as the lead product candidate from its adenovirus platform [5]. - The company has completed successful phase 2a clinical trials for CAN-2409 in non-small cell lung cancer and pancreatic ductal adenocarcinoma, and a pivotal phase 3 trial in localized prostate cancer [6][7]. Regulatory Designations - CAN-2409 has received Fast Track Designation from the FDA for multiple cancer treatments and has also been granted Regenerative Medicine Advanced Therapy Designation for localized prostate cancer [6][7]. - The company is preparing for a Biologics License Application submission for CAN-2409 in localized prostate cancer [2]. Future Outlook - Schoch expressed optimism about Candel's financial foundation and disciplined capital allocation, focusing on sustainable growth and advancing the clinical pipeline [4].
Larimar Therapeutics (LRMR) Earnings Call Presentation
2025-06-23 11:32
Larimar Therapeutics Nomlabofusp Regulatory Update June 2025 1 pro Forward-Looking Statements This presentation contains forward-looking statements that are based on the beliefs and assumptions of Larimar Therapeutics, Inc. ( "Company") and on information currently available to management. All statements contained in this presentation other than statements of historical fact are forward-looking statements, including but not limited to Larimar's ability to develop and commercialize nomlabofusp (CTI-1601) and ...
别被伪专业建议误导!精准干预与大众科普中间有边有界
Jing Ji Guan Cha Bao· 2025-06-21 00:45
想象一位深受焦虑障碍困扰的来访者,咨询师可能会用这样的表述引导:"让我们一起探索当你感到心 跳加速时,身体里那个'危险警报器'是如何被误触发的。"短短一句话,却蕴含着多重心理学原理。 它首先通过认知重构,将生理反应—心跳加速,重新定义为心理机制,危险警报器的误判,巧妙削弱了 症状带来的威胁感,让来访者不再对自身反应感到恐惧和无助; 其次,借助"警报器"这一隐喻,将抽象的情绪具象化,为来访者搭建起理解和管理情绪的桥梁,帮助他 们在混沌的情绪中找到抓手; 这样的表述还为后续的行为实验埋下伏笔,咨询师可能会据此布置"记录触发场景"的作业,将语言层面 的干预切实转化为可操作的改变。 (原标题:别被伪专业建议误导!精准干预与大众科普中间有边有界) 在心理健康领域,我们常常会遇到两种截然不同的语言体系:心理咨询师与来访者对话时的专业用语, 以及各类科普文章、媒体报道中面向大众的表述。这两种语言就像同一枚硬币的两面,虽同属心理学科 普范畴,却有着天壤之别的功能与使命,背后隐藏着深刻的专业逻辑与传播智慧。 心理咨询中的语言,堪称"靶向干预"的精准工具,严格遵循"症状-机制-干预"的医学模型。 就像网络上曾流行的"治愈"建议: ...
533.39亿元!前五个月青岛沪深交易所债券融资再创新高
Sou Hu Cai Jing· 2025-06-20 10:20
青岛日报社/观海新闻6月20日讯 观海新闻记者自青岛证监局获悉,今年前5个月,青岛市各类市场主体在沪深交易所累计发行债券融资533.39 亿元,同比增长10%。新增公司债券加权平均利率2.66%,较2024年下降32个基点,较5年期以上LPR利率低84个基点,全市新增交易所债券发 行主体6家。 不仅仅是融资总量的提升和融资成本的下降,在有效助力科技创新、助力城投产业化转型、推动存量资产盘活等方面,交易所债券也发挥积极 作用。 赋能科技创新,服务新质生产力 科技创新是发展新质生产力的"牛鼻子"。为了支持科技创新,银行间债券市场和交易所债券市场推出科技创新债券。2021年沪深交易所启动科 技创新债券试点,2022年进入常态化发行。2025年5月7日,中国人民银行、中国证监会联合发布《关于支持发行科技创新债券有关事宜的公 告》,从扩大发行范围、丰富产品体系、完善配套支持机制等方面,对支持科技创新债券发行提出多项举措。紧随其后,上交所、深交所、北 交所、交易商协会等发布实施细则。 5月30日,山东融发腾达产业发展集团有限公司在交易所发行青岛首单高成长产业债暨新政后首单科技创新公司债券5亿元;6月3日,青岛融合 产业发 ...
Why we don't sleep | Aisha Cortoos | TEDxUHasselt
TEDx Talks· 2025-06-18 16:37
Hi everyone. Have you ever been in a situation where you came home from work, very busy day, and you were quite tired, maybe even exhausted, and so you decided to go to bed just a little bit earlier? You're lying in bed and after 30 minutes or so you suddenly realize I am not falling asleep and then this feeling creeps up on you a jolt of anxiety, frustration and you start to think about all the reasons why you should fall asleep right now. Maybe you have an important meeting, a deadline, an exam, a TED tal ...
Critcal Compassion: A Marriage to Save Our Worlds | Angelyna Siahaan | TEDxYouth@MISJ
TEDx Talks· 2025-06-18 16:32
Does anyone here read romance novels? Yeah, I see you over there. I love romance novels. And there are so many different tropes, right? There's the childhood best friends to lovers, second chance romance, fake dating, but I have to say the one that takes the cake for me. My absolute favorite trope of all has to be enemies to lovers. I mean, think about it. These are two people with polar opposite beliefs to each other. And imagine when the stakes are really high. Think Romeo and Juliet. The Montigues and th ...
Problems With Humans | Nikolay Grigorov | TEDxYouth@AASSofia
TEDx Talks· 2025-06-18 16:25
Okay, let me show you something. Something big is happening around the world and everyone is talking about it. In fact, constant discussion has made new tech seem like it's constantly shouting AI here to save more like destroy the world.People are scared. It is hard to go online these days without encountering AI content, often highlighting inspiring opportunities for its use, but always delving into potential dangers to keep us on edge. However, in the minds of international conglomerates, AI is just anoth ...
How to reconnect with nature | Mark Walvoord | TEDxUCO
TEDx Talks· 2025-06-18 15:50
Environmental Impact & Climate Change - Human activity has increased greenhouse gases, leading to a 1.1°C temperature rise over the last century [2] - This temperature increase has caused an 8-inch rise in ocean levels due to melting glaciers [2] - Climate change has put 3.6 billion people at risk, leading to 15 times greater mortality in the last decade for those individuals [2] - Oklahoma County has experienced 3.2% fewer days below freezing per decade [2] Biophilia Hypothesis & Ecological Identity - The biophilia hypothesis suggests humans evolved to be connected with nature [1] - Empirical studies show that connection to nature leads to physical, mental, cognitive, and affective health benefits [1] - Integrating nature components into built environments can provide similar health benefits [1] - Centralizing ecological identity, seeing oneself as part of nature, is crucial for promoting pro-nature behaviors [2][3] Actions for Reconnection - Increase eco-literacy by learning about nature, climate, and sustainable choices [2] - Spend more time in nature to mitigate climate challenges and eco-anxiety [2] - Critically reflect on one's place in nature through mindfulness and dialogue [3][5] - Engage in dialogue with others to question assumptions and worldviews about nature [6]
Middle East: IAEA's Grossi on Iran Nuclear Sites Damage, Risks
Bloomberg Television· 2025-06-18 12:11
The UN nuclear watchdog saying enrichment facilities in Iran have taken direct military strikes. Joining us now is, I'm so pleased to say, the IAEA Director General Rafael Grossi. Director General, you've had a very busy couple of weeks.Thank you so much for making time for us. I want to just start with what damage has been done and what remains operational in Iran. Well, thank you very much.A pleasure to be with you. There has been a number of of there have been a number of attacks since the beginning of t ...