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Forbes· 2025-07-16 04:30
McDonald’s AI Breach Reveals The Dark Side Of Automated Recruitment https://t.co/HJ0kDmFTP4 https://t.co/uoeYjEOUwl ...
Akeso Announces First Patient Enrolled in the Phase III Trial(AK112-312/HARMONi-GI6)of Ivonescimab for First-Line Treatment of Advanced Metastatic Colorectal Cancer
Prnewswire· 2025-07-16 01:47
Core Viewpoint - Akeso, Inc. has initiated a Phase III clinical trial for ivonescimab as a first-line treatment for advanced metastatic colorectal cancer (mCRC), addressing a significant unmet clinical need in this area [1][2][7]. Industry Overview - Colorectal cancer is the third most common cancer globally and the second leading cause of cancer-related deaths, with over 1.9 million new cases and approximately 904,000 deaths reported in 2022 [3]. - About 95% of mCRC cases are classified as microsatellite stable (MSS) or proficient mismatch repair (pMMR), which traditionally show poor responses to immunotherapy [3]. - Current standard treatments for mCRC include chemotherapy combined with targeted therapies, but the overall efficacy remains limited, with a five-year survival rate for advanced patients of less than 20% [4]. Company Initiatives - The Phase III trial (AK112-312/HARMONi-GI6) aims to validate the clinical benefits of ivonescimab, which has shown promising Phase II efficacy data in combination with chemotherapy for MSS/pMMR-type mCRC [5][7]. - The combination of ivonescimab with FOLFOXIRI demonstrated an overall response rate (ORR) of 81.8% and a disease control rate (DCR) of 100%, indicating compelling anti-tumor activity in this difficult-to-treat patient population [6]. Future Prospects - If successful, ivonescimab could provide a novel first-line immunotherapy treatment option for patients with advanced mCRC, potentially improving outcomes compared to existing therapies [7].
Vance Boelter indicted on federal charges in killing of Minnesota lawmaker and her husband
NBC News· 2025-07-15 22:55
A grand jury indicting a Minnesota man on federal murder charges in the death of a state lawmaker and her husband last month. He's also accused of seriously hurting a state senator and his wife. Officials have described the attacks as politically motivated.Attorneys for the suspect did not immediately return a request for comment. ...
Algoma Steel Announces Conference Call and Provides Guidance for the Second Quarter 2025
Globenewswire· 2025-07-15 21:30
Core Viewpoint - Algoma Steel Group Inc. is set to release its Q2 2025 financial results on July 29, 2025, with a conference call scheduled for July 30, 2025, to discuss the results and recent developments [1][3] Financial Performance - Total steel shipments for the quarter are expected to be approximately 472,000 tons [2] - Adjusted EBITDA is anticipated to be in the range of ($30) million to ($35) million [2] Company Strategy and Operations - The CEO highlighted that the results were in line with expectations, particularly noting strength in the plate business despite macroeconomic uncertainties and tariff policies affecting the sector [3] - Algoma is advancing its transformation into one of North America's greenest steel producers, having achieved first arc and first steel production from its electric arc furnace project [3][8] Company Overview - Algoma is a fully integrated producer of hot and cold rolled steel products, including sheet and plate, and is a key supplier in North America [7] - The company is modernizing its plate mill and adopting electric arc technology to significantly lower carbon emissions, emphasizing its commitment to environmental stewardship [8]
Hancock Whitney HWC Q2 2025 Earnings Transcript
The Motley Fool· 2025-07-15 21:29
Core Insights - The company reported an expansion in Net Interest Margin (NIM) by six basis points in Q2 2025, indicating improved profitability [2][15] - Adjusted Return on Assets (ROA) was 1.37% for Q2 2025, reflecting transaction expenses related to the Sable Trust acquisition [3][20] - Adjusted net income decreased slightly to $118 million, or $1.37 per share, compared to $120 million, or $1.38 per share, in the previous quarter [3][20] - Pre-Provision Net Revenue (PPNR) increased by $5 million, or 3%, reaching 1.95% of assets [3][20] - Fee income rose by $4 million, or 4%, primarily driven by trust fees from the Sable Trust acquisition [4][20] Financial Performance - Net Interest Income (NII) increased by $7 million, or 2%, quarter-over-quarter [3][20] - Expenses rose by $5 million, or 2%, after adjusting for one-time items, with $2.5 million attributed to the Sable Trust acquisition [4][20] - Efficiency Ratio improved to 54.91% from 55.22% in the previous quarter, indicating better cost management [5][21] - Loans grew by $364 million, representing 6% annualized linked-quarter growth, with guidance for low single-digit annual growth remaining unchanged [5][15] Deposits and Funding - Deposit balances decreased by $148 million, primarily due to certificate of deposit (CD) run-off and reduced public funds [5][16] - Demand Deposit Account (DDA) mix increased to 37%, with management guiding for 37%-38% by year-end 2025 [5][24] - CD maturities repriced from 3.85% to 3.59%, with an 86% renewal rate; an additional $3.6 billion is expected to mature in the second half of 2025 [6][23] Capital and Shareholder Returns - Tangible common equity (TCE) stood at 9.84% and common equity Tier 1 at 14.03% post-acquisition [7][25] - The company repurchased 750,000 shares, spending approximately $40 million, with plans to maintain this capital return pace [8][26] - Management expects a common equity Tier 1 operating level of 11%-11.5% and a TCE comfort zone near 8% [9][29] Credit Quality - Allowance for Credit Losses (ACL) was maintained at 1.45% of loans, down four basis points from the last quarter [7][25] - Net charge-offs increased to 31 basis points, with full-year 2025 guidance unchanged at 15-25 basis points [7][25] - Criticized commercial loans declined by 4% to $594 million, and nonaccrual loans fell by 9% to $95 million, indicating stable credit quality [7][25] Growth Initiatives - The company added ten new bankers and finalized five new financial center locations in the Dallas area, with three openings slated for late 2025 and the remainder in early 2026 [8][17] - Management expects continued CD repricing at lower rates, forecasting at least an 81% renewal rate in the second half of 2025 [12][24] - The organic hiring plan targets a compounded 10% increase in bankers annually, with flexibility to exceed this if high-quality talent becomes available [12][76]
Bipartisan bill to provide legal status to certain migrants is not ‘amnesty’: Republican co-sponsor
NBC News· 2025-07-15 21:04
As the Trump administration ramps up its mass deportation efforts today, a group of bipartisan lawmakers announced a bill that would provide legal status for some undocumented immigrants. The Dignity Act, sponsored by Florida Republican Congresswoman Maria Salazar and Texas Democratic Congresswoman Veronica Escobar, would allow undocumented immigrants who have been in the US since before 2021 to apply for up to 7 years of legal status with work authorization, provided that they pay restitution and check in ...
Cricut to Announce Second Quarter 2025 Financial Results on August 5, 2025
Globenewswire· 2025-07-15 20:05
SOUTH JORDAN, Utah, July 15, 2025 (GLOBE NEWSWIRE) -- Cricut, Inc. (“Cricut”) (NASDAQ: CRCT), the creative technology company that has brought a connected platform for making to millions of users worldwide, today announced it will report its financial results for the second quarter ended June 30, 2025 after the U.S. markets close on Tuesday, August 5, 2025. Cricut management will host a conference call and webcast to discuss the results that afternoon at 3:00 p.m. Mountain Time (5:00 p.m. Eastern Time). A l ...
Can OXY's Integrated Portfolio Continue to Create Long-Term Value?
ZACKS· 2025-07-15 15:51
Core Insights - Occidental Petroleum Corporation (OXY) is distinguished in the oil and gas sector due to its strategically integrated portfolio, which enhances operational efficiency and supports long-term growth in shareholder value [1] Upstream Operations - Occidental's upstream strength is highlighted by its leadership in the Permian Basin, where it possesses extensive low-cost acreage, leading to consistent production growth and operational efficiencies [2] - The integration of midstream operations allows Occidental to optimize transportation costs and maintain robust margins, even during price downturns [2] Chemical Manufacturing - OxyChem serves as a valuable hedge through the production of essential basic chemicals and PVC, contributing to earnings diversification and stabilizing overall performance amid fluctuating commodity prices [3] Capital Allocation and Financial Health - With a disciplined capital allocation strategy and ongoing debt reduction, Occidental is positioned to deliver sustainable shareholder returns, supported by its balanced portfolio across oil, gas, chemicals, and infrastructure [4] Integrated Business Model Benefits - Oil and gas companies benefit from integrated assets by enhancing cost efficiency, improving supply-chain control, and ensuring stable cash flows across fluctuating commodity cycles [5] Earnings Performance - Occidental has consistently beaten earnings estimates over the past four quarters, with an average surprise of 24.3% [7][9] Stock Valuation - Occidental's shares are currently trading at a premium, with a trailing 12-month EV/EBITDA of 5.27X compared to the industry average of 4.91X [10] - The company's shares have increased by 19.2% over the past three months, outperforming the Zacks Oil and Gas-Integrated-United States industry's growth of 12.4% [12]
Digital asset ETPs surge in Q2 as investors flock to regulated crypto exposure, Fineqia analysis shows
Proactiveinvestors NA· 2025-07-15 15:46
About this content About Angela Harmantas Angela Harmantas is an Editor at Proactive. She has over 15 years of experience covering the equity markets in North America, with a particular focus on junior resource stocks. Angela has reported from numerous countries around the world, including Canada, the US, Australia, Brazil, Ghana, and South Africa for leading trade publications. Previously, she worked in investor relations and led the foreign direct investment program in Canada for the Swedish government ...
Mike Waltz faces grilling from Senators in UN confirmation hearing after Signal-gate
MSNBC· 2025-07-15 14:55
So Ryan, Democrats have warned this is going to be a brutal hearing. What do we expect. Well, there's no doubt that Democrats feel as though they have not gotten the answers that they've been looking for as it relates to this controversy over this signal chat that appeared to provide sensitive information about a military operation in which a journalist was inadvertently added to.They have questioned other administration officials about it in a public forum, most specifically the Secretary of Defense Pete H ...