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Disc Medicine Announces Multiple Presentations Across Portfolio at the European Hematology Association (EHA) 2025 Congress
Globenewswire· 2025-05-14 13:30
Poster presentations across all programs, including data from HELIOS long-term extension trial of bitopertin in erythropoietic protoporphyria (EPP), additional durability data from Phase 1b study of DISC-0974 in anemia of myelofibrosis (MF), and additional data from DISC-3405 studies in healthy volunteersManagement will host a corporate update conference call on Monday June 16 at 8:00 am ET / 2:00 pm CEST WATERTOWN, Mass., May 14, 2025 (GLOBE NEWSWIRE) -- Disc Medicine, Inc. (NASDAQ:IRON), a clinical-stage ...
Connect Biopharma Initiates Phase 2 Seabreeze STAT COPD Study Evaluating Rademikibart for the Treatment of Acute Exacerbations in COPD
Globenewswire· 2025-05-14 13:00
– Expect to report topline data from the Seabreeze STAT COPD study in 1H 2026 – SAN DIEGO, May 14, 2025 (GLOBE NEWSWIRE) -- Connect Biopharma Holdings Limited (Nasdaq: CNTB) (Connect Biopharma, Connect or the Company), a clinical-stage biopharmaceutical company focused on transforming acute and chronic care of asthma and chronic obstructive pulmonary disease (COPD), today announced the initiation of its Phase 2 Seabreeze STAT COPD study (NCT06940154) following written agreement on the final study protocol f ...
TScan Therapeutics (TCRX) 2025 Conference Transcript
2025-05-13 23:40
Summary of T SCAN Therapeutics Conference Call Company Overview - The conference featured T SCAN Therapeutics, represented by CEO Gavin Macbeth, at BofA's 2025 health care conference [1] Core Insights and Arguments - T SCAN is developing a program called Orca 21, which aims to combine IL-23 and IL-17 therapies for psoriasis treatment. The strategy involves using IL-17 for rapid skin clearance followed by IL-23 for maintenance [3][4] - The company is currently in Phase 1 clinical trials for the Orca 1 program, with results expected in the second half of the year. A Phase 2 study will also commence in the same timeframe, with psoriasis data anticipated next year [5][6] - T SCAN has raised over $475 million last year, providing sufficient funding for ongoing clinical trials and a runway for an additional year without needing further capital [6] Key Upcoming Events - Key milestones include: - Phase 1 readout for Orca 1 in the second half of this year - Phase 2 study initiation for psoriasis in the second half of this year - Pharmacokinetic (PK) data expected in the first half of next year [5][6] Important Metrics - The company aims for a 50-day half-life for the molecule to enable six-month dosing and a 75-day half-life for annual dosing, which would be a significant advancement in treatment options [9][10] Additional Considerations - The combination therapy approach has garnered excitement from physicians, indicating potential market interest and acceptance [4] - The reproducibility of psoriasis data across trials is highlighted as a critical factor for the company's future success [5]
定价逻辑切换,业内建议:债市交易应保持谨慎
news flash· 2025-05-13 21:40
贸易争端缓和后,全球债市定价逻辑切换,债券长端收益率快速上行,债市回调压力加大。业内人士建 议,当前投资者应适度控制久期,择机调整资产配置,短债基金和短期理财产品或成稳健选择;持有美 元理财产品的投资者,则需警惕汇率波动与资本利得双重损失。 ...
Rani Therapeutics Reports First Quarter 2025 Financial Results; Provides Corporate Update
Globenewswire· 2025-05-13 20:05
- Announced preclinical data demonstrating the bioequivalence of RT-114, a bispecific GLP-1/GLP-2 receptor agonist (PG-102), delivered orally via the RaniPill® capsule, to subcutaneous administration of PG-102 - - Phase 1 study for RT-114 for the treatment of obesity expected to initiate in mid-2025 - - Announced preclinical data demonstrating successful oral delivery of semaglutide via RaniPill® capsule - SAN JOSE, Calif., May 13, 2025 (GLOBE NEWSWIRE) -- Rani Therapeutics Holdings, Inc. (“Rani Therapeutic ...
Buy 5 Health and Fitness Stocks to Enhance Your Portfolio Returns
ZACKS· 2025-05-12 14:10
Industry Overview - Health and fitness companies focus on improving physical well-being through products and services such as gym memberships, fitness equipment, nutritional supplements, and wellness programs [1] - The industry benefits from consistent demand driven by growing global awareness of health issues and the importance of physical fitness, supported by rising rates of lifestyle-related diseases and a growing emphasis on preventive healthcare [3] - Diverse revenue streams, including subscriptions, product sales, and services, make the health and fitness sector attractive to investors seeking long-term gains [4] Investment Opportunities - Five recommended stocks in the health and fitness space with favorable Zacks Rank include Sprouts Farmers Market Inc. (SFM), DexCom Inc. (DXCM), Hims & Hers Health Inc. (HIMS), United Natural Foods Inc. (UNFI), and GoodRx Holdings Inc. (GDRX) [2] Company Highlights Sprouts Farmers Market Inc. (SFM) - Focus on product innovation, e-commerce, private label offerings, and targeted marketing has led to better-than-expected fourth-quarter 2024 results, with both top and bottom lines growing year over year [6] - Expected net sales growth of 10.5% to 12.5% and comparable store sales increase of 4.5% to 6.5% for 2025 [7] - Projected revenue and earnings growth rates of 13.7% and 33.6%, respectively, for the current year [8] DexCom Inc. (DXCM) - Benefiting from strong contributions from the Sensor segment and both domestic and international revenue growth [10] - Expected revenue and earnings growth rates of 14.3% and 23.2%, respectively, for the current year [11] Hims & Hers Health Inc. (HIMS) - Addresses a $360 million U.S. total addressable market across various healthcare specialties, with over 2 million subscribers driving recurring revenues [12] - Expected revenue and earnings growth rates of 58.5% and more than 100%, respectively, for the current year [13] United Natural Foods Inc. (UNFI) - Demonstrating strong growth supported by wholesale momentum and demand for natural and organic products [14] - Expected revenue and earnings growth rates of 1.9% and more than 100%, respectively, for the current year [16] GoodRx Holdings Inc. (GDRX) - Offers a price comparison platform for prescription drugs, enabling consumers to save on purchases [17] - Expected revenue and earnings growth rates of 4% and 14.7%, respectively, for the current year [19]
CervoMed Reports First Quarter 2025 Financial Results and Provides Corporate Updates
Globenewswire· 2025-05-12 12:00
Reported positive 16-week results from the extension phase of the Phase 2b RewinD-LB trial, demonstrating proof-of-concept for neflamapimod as a potential treatment for dementia with Lewy bodies (DLB) Plan to initiate Phase 3 trial of neflamapimod in DLB in mid-2026 following meeting with regulatory authorities Initiating separate Phase 2a trials to evaluate neflamapimod in patients with primary progressive aphasia and patients in the recovery phase after ischemic stroke BOSTON, May 12, 2025 (GLOBE NEWSWIRE ...
CytomX Therapeutics Announces Pricing of $100 Million Underwritten Offering of Common Stock
Globenewswire· 2025-05-12 10:50
SOUTH SAN FRANCISCO, Calif., May 12, 2025 (GLOBE NEWSWIRE) -- CytomX Therapeutics, Inc. (NASDAQ:CTMX), a leader in the field of masked, conditionally activated biologic therapeutics, today announced the pricing of an underwritten offering of 76,923,076 shares of its common stock at an offering price of $1.30 per share, before underwriting discounts and commissions. All of the shares are being offered by the Company. The gross proceeds from the offering are expected to be approximately $100 million before de ...
CytomX Therapeutics Announces First Quarter 2025 Financial Results and Provides Business Update
Globenewswire· 2025-05-12 10:15
Core Insights - CytomX Therapeutics announced positive interim clinical results for CX-2051, an EpCAM-directed antibody-drug conjugate (ADC) for advanced colorectal cancer (CRC), highlighting its strategic importance for the company [3][7] - The company has initiated dose expansions for CX-2051 at 7.2 mg/kg, 8.6 mg/kg, and 10 mg/kg, with a Phase 2 study planned for the first half of 2026 [7][3] - Financial results for Q1 2025 show total revenue of $50.9 million, an increase from $41.5 million in Q1 2024, driven by collaborations with Bristol Myers Squibb and Amgen [9][10] Pipeline Program Updates - CX-2051 is currently in a Phase 1 dose escalation study, with an update on data from at least 70 patients expected by Q1 2026 [7] - CX-801, a PROBODY interferon alpha-2b, is also in development, with initial Phase 1a translational data expected in the second half of 2025 [7][5] - The company is focusing on combination therapy with CX-801 and KEYTRUDA, aiming to initiate this in 2025 [7] Financial Overview - As of March 31, 2025, the company reported cash, cash equivalents, and investments totaling $79.9 million, down from $100.6 million at the end of 2024 [8] - Total operating expenses for Q1 2025 were $28.3 million, a decrease from $29.8 million in Q1 2024, with R&D expenses at $18.9 million, down from $22.1 million [10][11] - The net income for Q1 2025 was $23.5 million, compared to $13.8 million in Q1 2024, reflecting improved operational efficiency [18]
Talen Energy: Disappointing Q1 Earnings, But Strong Demand Keeps This Stock A Hold
Seeking Alpha· 2025-05-11 09:12
The utility energy industry is undergoing a unique transformation driven by the global push toward decarbonization, technological innovation, and evolving regulatory landscapes. There is a surge in renewable energy investment, and demand is rapidly increasing due to AI-driven dataI am an investment author with passion for finance and global markets. I enjoy gearing toward economic analysis, specifically on a macro level. Through current and forward looking market trends, fundamental and technical analysis, ...