Antibody complement therapeutics

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Dianthus Therapeutics Highlights Claseprubart Data Presentations Planned for 2025 AANEM Annual Meeting
Globenewswire· 2025-10-02 12:00
NEW YORK and WALTHAM, Mass., Oct. 02, 2025 (GLOBE NEWSWIRE) -- Dianthus Therapeutics, Inc. (Nasdaq: DNTH), a clinical-stage biotechnology company dedicated to advancing the next generation of antibody complement therapeutics to treat severe autoimmune diseases, today announced that the results of the Phase 2 MaGic trial of claseprubart in generalized Myasthenia Gravis (gMG) will be presented in an oral presentation at the American Association of Neuromuscular and Electromagnetic Medicine (AANEM) Annual Meet ...
Dianthus Therapeutics Appoints Simon Read, Ph.D., to Board of Directors
Globenewswire· 2025-05-22 20:10
Core Insights - Dianthus Therapeutics has appointed Simon Read, Ph.D., to its Board of Directors, bringing over 30 years of biopharmaceutical leadership and expertise [1][2] - The company is focused on advancing its mid- and late-stage clinical programs, particularly the DNTH103 therapy for severe autoimmune diseases [2][3] - Lonnie Moulder will transition from the Board, having played a significant role in the company's growth from a private entity to a publicly traded company with three ongoing clinical trials [2] Company Overview - Dianthus Therapeutics is a clinical-stage biotechnology company dedicated to developing next-generation antibody complement therapeutics aimed at treating severe autoimmune and inflammatory diseases [3] - The company is based in New York City and Waltham, Massachusetts, and is led by an experienced team of biotech and pharma executives [3] Leadership Background - Dr. Read previously served as CEO and founder of Mariana Oncology until its acquisition by Novartis in 2024 and as Chief Scientific Officer at Ra Pharma until its acquisition by UCB in 2020 [1][2] - He has held leadership roles in R&D at major pharmaceutical companies, including GlaxoSmithKline, AstraZeneca, and Roche/Genentech, contributing to the development of well-known immunology drugs [2] Clinical Development - The company is currently executing three clinical programs, with Phase 2 MaGic results for DNTH103 expected in September [3] - Dr. Read expressed confidence in the potential of DNTH103 as a best-in-class therapy for patients with severe neuromuscular conditions [3]
Dianthus Therapeutics Completes Enrollment of Phase 2 MaGic Trial of DNTH103 in Generalized Myasthenia Gravis With Top-Line Results Expected in September
Globenewswire· 2025-05-05 11:00
MaGic trial exceeded enrollment target of 60 patients Top-line results anticipated this September will be the first of three DNTH103 catalysts by YE'26 Building a neuromuscular franchise with DNTH103 in gMG, CIDP and MMN with a potential best-in-class, potent classical pathway inhibitor intended as a self-administered autoinjector dosed once every two weeks NEW YORK and WALTHAM, Mass., May 05, 2025 (GLOBE NEWSWIRE) -- Dianthus Therapeutics, Inc. (Nasdaq: DNTH), a clinical-stage biotechnology company dedicat ...