Summary of Hangzhou Tigermed Consulting Conference Call Industry Overview - The conference call focused on China's clinical Contract Research Organization (CRO) industry, highlighting significant trends and developments from 2019 to 2025 [2][3]. Key Points 1. **CRO Outsourcing**: Approximately 50% of clinical trials conducted in China were outsourced to CROs during the period from 2019 to 2025 [3]. 2. **Market Growth Rates**: The market's compound annual growth rate (CAGR) slowed from 25% during the COVID-19 period (2020-2022) to 4% in the post-COVID period (2023-2024). However, it is projected to accelerate to 13% from 2025 to 2028 according to Frost & Sullivan and the Human Genetic Resources Administration [3]. 3. **CRO Overcapacity**: The number of Chinese CROs decreased from 500 in 2024 to 480 in 2025, while the average number of annual trials conducted per CRO increased from 35.6 to 42.9 [3]. 4. **Clinical Trial Approvals**: In 2025, the number of clinical trial approvals (INDs) and Phase 1 trial starts in China rose by 19% and 13%, reaching 2,703 and 1,168 respectively [4]. 5. **Outlicensing Deals**: China executed 178 novel drug outlicensing deals to the US and Europe from 2024 to 2025, accounting for 14% of the world's total, an increase from 85 deals (9% of the total) from 2022 to 2023 [4]. 6. **Biotech Funding**: Chinese biotech companies raised $5.2 billion from private equity and venture capital in 2025, up from $4.2 billion in 2024. Total upfront payments from outlicensing also increased from $4.4 billion to $7.5 billion [4]. 7. **Global Drug Pipeline Contribution**: China now contributes approximately 30% to the global innovative drug pipeline [5]. 8. **Patient Enrollment Efficiency**: The average time to enroll a patient in China for an oncology trial is 60 days, compared to the global median of 150 days [5]. 9. **New Orders for Tigermed**: New orders for Tigermed increased across various customer types from January to November 2025, with biotech companies and multinational corporations (MNCs) being the largest contributors at 38% and 25% respectively. MNCs are responsible for 25-30% of Phase 3 trials in China [5]. 10. **Trial Pricing Trends**: Prices for Phase 1 and 2 trials reached their lowest point in 2024 and began to rise in 2025, aligning with levels similar to 2023 but remaining significantly below the peak levels seen during COVID-19 in 2022 [6]. Financial Metrics for Hangzhou Tigermed Consulting - **Stock Rating**: Overweight - **Price Target**: RMB 81.00, representing a 35% upside from the current price of RMB 60.03 as of January 20, 2026 [7]. - **Market Capitalization**: RMB 52.383 billion [7]. - **Revenue Projections**: Expected revenue growth from RMB 6.603 billion in 2024 to RMB 8.458 billion by 2027 [7]. - **Earnings Per Share (EPS)**: Projected EPS growth from RMB 0.46 in 2024 to RMB 1.85 in 2027 [7]. - **Return on Equity (ROE)**: Expected to increase from 1.9% in 2024 to 7.2% in 2027 [7]. Risks Identified - **Upside Risks**: Faster growth in clinical R&D outsourcing, accelerated recovery of domestic demand, and new collaboration deals [13]. - **Downside Risks**: Slower-than-expected recovery in clinical CRO demand, rising pricing pressure, geopolitical risks, and potential impairment of goodwill and intangible assets [13]. This summary encapsulates the critical insights from the conference call regarding the clinical CRO industry in China and the financial outlook for Hangzhou Tigermed Consulting.

Summary of Hangzhou Tigermed Consulting Conference Call Company Overview - **Company**: Hangzhou Tigermed Consulting (300347.SZ) - **Industry**: China Healthcare - **Market Capitalization**: Rmb46,720 million - **Current Stock Price**: Rmb53.54 - **Price Target**: Rmb93.10, indicating a potential upside of 74% [7][10] Key Financial Highlights - **3Q25 Revenue**: Rmb1,775 million, up 3.9% YoY - **3Q25 Earnings**: Rmb637 million, up 98.7% YoY - **Recurring Earnings**: Rmb115 million, down 54.3% YoY - **Net New Orders Backlog**: Rmb7.0 billion, up approximately 15% YoY [3][10] Core Insights - **Recovery Cycle**: The company is entering a recovery phase as old projects are phased out, with a sequential revenue improvement of 5% in 3Q25. However, margins are still pressured due to declining average unit prices YoY against a fixed cost base [3][4] - **New Orders Composition**: In 3Q25, 30.3% of new orders by value came from multinational pharma companies, while 17.5% came from large Chinese pharma [3] - **Clinical Trials**: There was an increase in new orders from Phase 1-2 clinical trials, reflecting improved funding conditions. Management noted a clear recovery in private financing during 3Q25, with aggregate financing in China reaching its highest value for a single quarter since 2022 [3][4] Industry Dynamics - **CRO Industry Growth**: The global biopharma sector is re-accelerating investments in R&D and clinical trials, with China's CROs providing cost and efficiency advantages. Key drivers include: - Increased private financing activity supporting preclinical and early-phase drug pipelines - Robust out-licensing activity in China, which is driving trial starts for additional indications and replenishing cash reserves of local biotechs [4] - **Industry Consolidation**: Potential normalization of supply and average prices due to industry consolidation, as evidenced by a peer's recent divestment of its CRO segment [5] Risks and Considerations - **Upside Risks**: Faster growth in clinical R&D outsourcing, accelerated recovery of domestic demand, and new collaboration deals [13] - **Downside Risks**: Slower-than-expected recovery in clinical CRO demand, rising pricing pressure, geopolitical and currency risks, and potential impairment of goodwill and intangible assets [13] Valuation Metrics - **EPS Estimates**: Expected EPS for FY25 is Rmb0.96, with projections of Rmb1.29 for FY26 and Rmb1.99 for FY27 [7] - **P/E Ratio**: Projected P/E ratios are 107.5 for FY25, decreasing to 25.3 by FY27 [7] - **ROE**: Expected ROE is projected to increase from 2.1% in FY25 to 8.3% by FY27 [7] Conclusion Hangzhou Tigermed Consulting is positioned to benefit from a recovery in the biopharma sector, supported by increasing private financing and a growing backlog of new orders. The company’s strategic focus on early-phase clinical trials and the advantages offered by China's CRO landscape are expected to drive future growth, despite potential risks associated with market dynamics and competition.