Workflow
Drug Development Costs
icon
Search documents
The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
a16zยท 2025-11-14 16:08
Two venture capitalists dissect why biotech burns billions while China runs trials in weeks, and why the next Genentech won't look anything like the last one. Elliot Hershberg reveals the "three horsemen" strangling drug development as costs explode to $2.5 billion per approval, while Lada Nuzhna exposes how investigator-initiated trials in Shanghai are rewriting the competitive playbook faster than American founders can file INDs. When the infrastructure that built monoclonal antibodies becomes the commodi ...