Group 1 - The core viewpoint of the articles emphasizes that lifestyle factors have a more significant impact on health and aging than genetic factors [4][6][7] - A study involving 500,000 participants revealed that environmental factors account for 17% of mortality risk differences, while genetic susceptibility accounts for less than 2% [6][7] - Key environmental factors affecting biological aging include smoking, socioeconomic status, physical activity, and living conditions [6][7] Group 2 - Sleep quality is crucial for immune system function, with even one night of sleep deprivation significantly altering monocyte characteristics and increasing chronic inflammation risk [9][11][12] - Research indicates that sleep disorders are linked to chronic diseases such as type 2 diabetes and cardiovascular diseases [9][11] - Improving sleep quality may serve as an effective intervention strategy to reduce inflammation and enhance health [13] Group 3 - Short-term high-calorie diets can lead to long-term detrimental effects on brain function, even without immediate weight gain [14][17][18] - A study found that five days of high-calorie intake altered brain insulin response and reward sensitivity, mimicking patterns seen in obese individuals [17][18] - These changes in brain structure and function may create a vicious cycle that promotes overeating and metabolic disorders [18]