Core Insights - SenesTech, Inc. reported a 43% increase in revenues to $690,000 for Q3 2025, marking a record for the company, with Evolve® Rodent Birth Control product sales growing 77% year-over-year, now accounting for 85% of total revenue [7][4][1] Financial Highlights - Revenues increased to $690,000 from $482,000 in Q3 2024, representing a 43% growth [7] - Gross profit margin was reported at 62.8% [7] - Net loss for Q3 2025 was $1.3 million, an improvement from a loss of $1.5 million in Q3 2024 [7] - Adjusted EBITDA loss improved to $1.2 million, compared to $1.4 million in the same quarter of the prior year [7] - Cash and short-term investments totaled $10.2 million, providing a solid operating runway [7] Operational and Strategic Highlights - Evolve Rat and Evolve Mouse products, launched in 2024, grew 77% year-over-year and are the largest revenue drivers, representing 85% of total revenue [7] - E-commerce revenue increased by 55% year-over-year, with significant growth in Amazon sales [7] - Municipal revenue grew 139% year-over-year, driven by expanded deployments in cities like New York and Chicago [7] - Retail revenue surged 254% year-over-year, largely due to increased adoption by Ace Hardware and follow-on orders from Bradley Caldwell [7] - Revenue from pest management professionals increased by 29% year-over-year, contributing nearly 20% of overall revenue for Q3 2025 [7]

Core Insights - SenesTech, Inc. has launched its Evolve® Rat Birth Control® product on Lowes.com, marking a significant milestone in consumer accessibility and retail distribution [1][4][5] - Evolve Rat is the first soft bait targeting rat reproduction, providing a humane and sustainable solution to manage rat populations without poisons [2][4] - The partnership with Lowes, which has over 1,700 stores and $11 billion in online sales, is expected to enhance brand visibility and accelerate adoption among consumers [3][4] Company Overview - SenesTech focuses on humane pest management through fertility control, aiming to create healthier environments by reducing reliance on traditional poisons [5] - The company’s mission includes creating cleaner cities and healthier communities with effective and sustainable products [5] Market Opportunity - The launch on Lowes.com is seen as a strategic move to expand Evolve Rat's retail footprint, potentially leading to stronger revenue streams and increased market presence [4][8] - The product addresses a critical issue in pest management by targeting the root cause of population growth rather than merely increasing death rates [4][7]

Core Insights - SenesTech, Inc. will report its third quarter 2025 financial results on November 10, 2025, after market close, followed by a conference call at 5:00 p.m. Eastern time to discuss the results [1][2] Company Overview - SenesTech is focused on humane pest management through fertility control, having developed ContraPest®, the only U.S. EPA-registered contraceptive for both male and female rats, along with Evolve Rat and Evolve Mouse, which are EPA-designated minimum risk contraceptives for rodents [3] Conference Call Details - The conference call on November 10, 2025, will be accessible via a live webcast, with a replay available for 90 days on the company's Investor Relations website [2]

Core Insights - SenesTech, Inc. has launched a pilot program in Swampscott, Massachusetts, utilizing Evolve® Rat Birth Control to manage rat populations humanely without harsh chemicals [1][4] - The initiative aims to provide a sustainable solution to pest control, focusing on prevention rather than short-term elimination [4] Company Overview - SenesTech specializes in fertility control for pest management, having developed products like ContraPest and Evolve Rat, which are designed to be humane, effective, and sustainable [5] - The company’s mission is to improve public health by managing animal pest populations through innovative fertility control methods [5] Pilot Program Details - The pilot program is a collaboration with Speak Up for Animals and local advocate Debora Norman, aiming to protect public health while minimizing risks to children, pets, and wildlife [2] - Evolve Rat works by controlling rat reproduction, addressing the root cause of infestations, and has shown success in various settings across the country [3] Community Impact - Swampscott is one of the first communities in Massachusetts to implement this innovative pest control method, reflecting a commitment to safer and more responsible rodent management [4] - The pilot will be monitored closely, with potential expansion to additional neighborhoods in 2026 if successful [4]

Core Insights - SenesTech, Inc. has reported successful results from urban deployments of its Evolve™ Rat Birth Control in Hong Kong and San Francisco, demonstrating a faster and more sustainable approach to rodent control by combining fertility control with traditional rodenticides [1][3][5] Group 1: Urban Rodent Challenges - Global cities are facing persistent rodent issues due to dense infrastructure, hard-to-access breeding sites, and abundant food sources, leading to the inadequacy of traditional rodenticide programs over time [2] - Rodents have shown adaptability to poisons, resulting in unchecked reproduction despite aggressive control measures [2] Group 2: Integrated Pest Management Strategy - The integrated strategy employed in Hong Kong involved deploying Evolve's palatable soft bait alongside conventional rodenticide blocks, leading to a significant reduction in rodent sightings and no new litters detected within three months [3][4] - In San Francisco, a similar approach resulted in reduced visible rodent activity, decreased overall poison usage, and a measurable drop in new rodent births [4] Group 3: Industry Implications - The success of these deployments indicates that fertility control can serve as a practical tool for pest professionals, enhancing integrated pest management (IPM) programs and reducing reliance on rodenticides [5] - The company is preparing for a container-sized order from Hong Kong, signaling rapid expansion and increased demand for its products [5] Group 4: Market Opportunities - Fertility control solutions like Evolve align with evolving environmental regulations and public demand for humane, low-toxicity pest management, offering improved outcomes and better ROI for pest control professionals and property owners [6] - This trend indicates a rapidly growing global market for next-generation rodent control solutions that complement traditional methods [6]

Company Overview - SenesTech, Inc. is a leader in fertility control for managing animal pest populations, having developed products like ContraPest and Evolve, which are designed to be humane, effective, and sustainable [5]. - The company has entered into an exclusive distribution agreement with Asa Jaya Mandiri LTD (AJM) for the commercialization of Evolve™ in Indonesia, marking its eleventh international distribution agreement [1][4]. Industry Context - Rats are a significant threat to palm oil plantations in Indonesia, causing estimated yield reductions of 5-10% annually, which translates to potential economic losses of USD 540 million to USD 1.08 billion each year, given the palm oil market's value of approximately USD 10.8 billion in 2024 [2]. - The rapid reproduction and adaptability of rats to traditional control methods make long-term population management challenging, highlighting the need for effective fertility control solutions [3]. AJM Profile - Asa Jaya Mandiri LTD (AJM) is a prominent Indonesian trading company with a specialized pest management operation, committed to high quality and standards in its offerings [4][7]. - AJM has over a decade of experience and a diverse portfolio of products sourced globally, enabling it to cater to the unique needs of its customers [7].

As filed with the Securities and Exchange Commission on November 27, 2023 Registration No. 333-273370 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 AMENDMENT NO. 2 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SENESTECH, INC. (Exact name of registrant as specified in its charter) | | | (State or other jurisdiction of (Primary Standard Industrial (I.R.S. Employer incorporation or organization) Classification Code Number) Identification Number) 23460 N 19th Ave. ...

As filed with the Securities and Exchange Commission on November 22, 2023 Registration No. 333-273370 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 AMENDMENT NO. 1 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SENESTECH, INC. (Exact name of registrant as specified in its charter) | | | (State or other jurisdiction of (Primary Standard Industrial (I.R.S. Employer incorporation or organization) Classification Code Number) Identification Number) 23460 N 19th Ave. ...

As filed with the Securities and Exchange Commission on July 21, 2023 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 SENESTECH, INC. (Exact name of registrant as specified in its charter) (State or other jurisdiction of (Primary Standard Industrial (I.R.S. Employer incorporation or organization) Classification Code Number) Identification Number) Delaware 2879 20-2079805 23460 N 19th Ave., Suite 11 ...