Core Points - Karyopharm Therapeutics Inc. (KPTI) experienced a significant stock decline of 11.86 percent, dropping $0.68 to a price of $5.09 following the announcement of financing and capital structure transactions [1] - The company is expected to secure $100 million in funding, which will extend its cash runway into the second quarter of 2026 [1] Stock Performance - The current trading price of Karyopharm shares is $5.03, down from a previous close of $5.77 on the Nasdaq [2] - Shares opened at $4.65 and have fluctuated between $4.51 and $5.15 during the trading day, with a trading volume of 2.1 million shares, significantly higher than the average of 173,000 shares [2] - Over the past 52 weeks, Karyopharm shares have traded within a range of $3.51 to $16.95 [2]