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Could we detect breast cancer with your fingerprint? | Simona Francese | TEDxManchester
TEDx Talksยท 2025-06-16 17:01
Breast Cancer Statistics and Screening Challenges - Globally, breast cancer caused 670,000 deaths in 2022, with 11,500 deaths in the UK, equating to 32 deaths per day, and cases are predicted to rise to 70,000 by 2040 [1] - While death rates are falling by 44% due to interventions, better screening, and treatments, low screening uptake remains a concern, especially among underserved populations [1] - NHS backlogs, exacerbated by decades of underfunding and COVID-19, contribute to reduced resources and disproportion between screenings needed and available radiologists and mammographic equipment [1] - Accessibility problems are significantly worse for underserved populations, with cultural unacceptability, invasiveness, fear of radiation, and pain deterring women from undergoing mammography [1] - A survey revealed that 21% of 2,000 women cited embarrassment and fear of pain as reasons for avoiding screening [1] Fingerprint-Based Breast Cancer Screening Innovation - A novel fingerprint-based test is proposed as a non-invasive, radiation-free, and painless alternative to mammography, bypassing NHS backlogs and resource constraints [1] - The technology utilizes mass spectrometry (MALDI) to analyze molecular patterns in fingerprints, identifying proteins indicative of an individual's state, including potential biomarkers for breast cancer [1] - Research demonstrated the ability to differentiate between male and female fingerprints with 86% accuracy by analyzing protein profiles [2] - A study involving 135 samples from 15 women showed that a machine learning algorithm could distinguish between early breast cancer, benign conditions, and metastatic cancer with 97.8% accuracy [2] - The fingerprint test aims to reduce NHS costs, increase accessibility (potentially at GP practices or at home), improve compliance, and ultimately save lives [2]