XtalPi's AI + Robotics Platform Powers First Clinical Milestone for ReviR's Rare Neurological Drug RTX-117 [Accessibility Statement] Skip Navigation- RTX-117 is an investigational small molecule designed to modulate the Integrated Stress Response (ISR) pathway, with the goal of restoring protein translation homeostasis implicated in Charcot-Marie-Tooth disease (CMT) and Vanishing White Matter disease (VWM)- ReviR has dosed the first participant in a Phase 1 trial of RTX-117, initially evaluating safety, tol ...