Financial Data and Key Metrics Changes - The company reported a strong fiscal year 2025, with EPS and adjusted operating income both up 16% [4] - The stock price has compounded at 25% over the past several years, with a 55% increase recently [4] - Long-term operating income guidance has been raised to 6%-9% growth, with U.S. healthcare operating income growth expected at 9%-11% for 2026 [4][5] Business Line Data and Key Metrics Changes - The U.S. operating income growth is projected at 9%-11%, with a potential 10%-12% growth when excluding a 1% headwind from a competitor acquisition [5][6] - The specialty business continues to drive outsized growth, particularly in pharmaceutical utilization trends and sales of specialty products [7][8] Market Data and Key Metrics Changes - The international healthcare solutions segment saw weaker performance, with 85% of operating income coming from the U.S. and only 15% from international [50] - The 3PL market is identified as the fastest-growing part of the international distribution business, with improvements noted in the global specialty logistics business [51][53] Company Strategy and Development Direction - The company is focusing on expanding its MSO business, particularly in oncology and retina, to provide higher value services to physician practices [15] - A commitment to remain pharmaceutical-centric in all strategic moves, leveraging innovation in the pharmaceutical market and demographic trends for long-term growth [9][15] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in long-term growth driven by pharmaceutical innovation and demographics, despite expecting normalization in growth rates post-fiscal 2026 [9][10] - The company is optimistic about the international business for fiscal year 2026, with a turnaround in the global specialty logistics business noted [51][53] Other Important Information - The company plans to invest approximately $900 million in capital expenditures for infrastructure and technology in the current year [62] - A balanced capital deployment strategy includes strategic acquisitions, opportunistic share repurchases, and a commitment to increasing dividends [63][64] Q&A Session Summary Question: What are the key growth drivers for the MSO business? - The MSO business is evolving through organic growth and acquisitions, with a focus on providing management services to physician practices [15][17] Question: How does the company view potential headwinds from drug pricing? - The company has historically advocated for community providers and believes that pharmaceuticals are the most efficient form of care, which should mitigate potential pricing headwinds [24][25] Question: What is the impact of biosimilars on the business? - Biosimilars are expected to benefit the company from a distribution and GPO standpoint, as they offer higher margins compared to brand-name drugs [27][28] Question: How is the relationship with Walgreens affected by its privatization? - The relationship remains strong, with contracts in place until 2029, and the company continues to work on improving operational efficiencies [42][43] Question: What actions are being taken regarding the PharmaLex business? - The company is focusing on the more attractive parts of PharmaLex, particularly in pharmacovigilance, market access, and regulatory affairs, while evaluating strategic alternatives for less competitive segments [56][57]

Financial Data and Key Metrics Changes - Cencora achieved adjusted operating income and adjusted diluted EPS growth of 16% in fiscal 2025 [3][11] - Adjusted diluted EPS for Q4 was $3.84, a 15% increase, with consolidated revenue of $83.7 billion, up 6% [12][19] - Consolidated gross profit was $2.9 billion, up 18%, with a gross profit margin of 3.47%, an increase of 37 basis points [12][13] - Consolidated operating income was $1.0 billion, up 20% compared to the prior year quarter [13][19] - Consolidated revenue for fiscal 2025 was $321.3 billion, up 9% [19] Business Line Data and Key Metrics Changes - U.S. healthcare solutions segment revenue was $75.8 billion, up approximately 6% year-over-year, with operating income increasing by 25% to $872 million [15][16] - International healthcare solutions segment revenue was $7.9 billion, an increase of 8% on an as-reported basis, but operating income decreased by 2% [16][17] - GLP-1 products contributed $876 million, or 10% year-over-year growth, to the U.S. healthcare solutions segment [15][16] Market Data and Key Metrics Changes - The international healthcare solutions segment saw a rebound in global specialty logistics business, with shipment volumes returning to growth [17][56] - The U.S. healthcare solutions segment continues to benefit from strong utilization trends, particularly in specialty [15][52] Company Strategy and Development Direction - Cencora's strategy focuses on three growth priorities: leading with market leaders, enhancing patient access to pharmaceuticals, and strengthening its position in specialty [4][29] - The company is raising long-term guidance for adjusted operating income growth to 6-9% and adjusted EPS growth to 9-13% [4][28] - Significant investments totaling $1 billion through 2030 are planned to enhance distribution network and specialty distribution capacity [9][10] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in continued market growth and the strength of the business, emphasizing the importance of strategic investments [3][4] - The company is focused on enhancing productivity and efficiency in serving the pharmaceutical supply chain [5][10] - Management acknowledged the impact of losing an oncology customer but remains optimistic about future growth [26][40] Other Important Information - The company announced a 9% increase in its quarterly dividend, marking the 21st consecutive annual dividend increase [20] - A strategic review led to the identification of businesses that do not align closely with future strategy, including MWI Animal Health and certain components of Pharmalex [7][21] Q&A Session Summary Question: Strategic view on business and potential divestitures - Management emphasized a focused strategic execution and the importance of investing in areas aligned with their strategy [31][32] Question: Next steps for the MSO platform - Management discussed leveraging capabilities across MSO platforms and the potential for shared resources to enhance care delivery [36][37] Question: U.S. healthcare segment performance and growth durability - Management highlighted strong performance in the U.S. segment, with adjusted operating income growth of 25%, and expressed confidence in sustaining growth despite headwinds [39][40] Question: International business growth outlook - Management indicated confidence in returning to growth in the international segment, driven by strong demand for specialty logistics and a tailored portfolio [55][56] Question: Profitability and strategic alternatives for businesses in the "other" segment - Management confirmed that all businesses in the "other" segment are currently profitable and discussed the potential for strategic alternatives to enhance long-term success [59][60]