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Enlivex Therapeutics to Present Clinical Data of Allocetra in Osteoarthritis at EULAR 25 European Congress of Rheumatology
Globenewswire· 2025-06-10 12:30
Dr. Oren Hershkovitz, CEO, and Einat Galamidi, MD, CMO, will attend the conference and be available for meetings with stakeholders and members of the scientific community. Ness-Ziona, Israel, June 10, 2025 (GLOBE NEWSWIRE) -- Enlivex Therapeutics Ltd. (Nasdaq: ENLV, the "Company"), a clinical-stage macrophage reprogramming immunotherapy company, today announced that it will present a poster at the European Alliance of Associations for Rheumatology (EULAR) European Congress of Rheumatology, taking place June ...
Enlivex Announces Completion of Enrollment In The Phase II stage Of Its Phase I/II Trial Evaluating Allocetra In Patients With Moderate To Severe Knee Osteoarthritis
Newsfilter· 2025-04-21 12:30
Nes-Ziona, Israel, April 21, 2025 (GLOBE NEWSWIRE) -- Enlivex Therapeutics Ltd. (NASDAQ:ENLV, the "Company")), a clinical-stage macrophage reprogramming immunotherapy company, today announced that the Company completed enrollment of all patients in the Phase II stage of its randomized, controlled, blinded Phase I/II trial of Allocetra™ in patients with moderate to severe knee osteoarthritis. Overall, 133 patients were randomized and treated in the Phase II stage.   Oren Hershkovitz, Ph.D, CEO of Enlivex, co ...
Enlivex Announces the Dosing of the First Patient in a Phase I Trial Evaluating Allocetra in Patients with TMJ Osteoarthritis
Newsfilter· 2025-04-03 12:00
Company Overview - Enlivex Therapeutics Ltd. is a clinical-stage company focused on macrophage reprogramming immunotherapy, specifically developing Allocetra™ [1][6] - Allocetra™ is designed as a universal, off-the-shelf cell therapy aimed at restoring macrophage homeostasis, which is critical for immune system balance and addressing life-threatening conditions [4][6] Clinical Trial Announcement - The first patient has been dosed in a Phase I trial to evaluate the safety, tolerability, and initial efficacy of Allocetra™ for treating temporomandibular joint (TMJ) osteoarthritis [1][3] - The trial is being conducted by the Rheumatology Unit and the Department of Oral and Maxillofacial Surgery at Sheba Medical Center, which is ranked among the top 10 hospitals globally [2] Trial Details - The trial aims to recruit six patients who have not adequately responded to conventional therapies for TMJ osteoarthritis [3] - Primary safety endpoints will measure the frequency and severity of adverse events, while efficacy endpoints will assess changes in TMJ pain, joint functionality, and other disease parameters over 12 months [3] TMJ Osteoarthritis Insights - TMJ disorders affect 5% to 12% of the global population, with an annual health cost estimated at $4 billion [5][8] - TMJ osteoarthritis is the most common form of arthritis in the TMJ, leading to pain and stiffness, and currently lacks effective long-term treatments [5][8]
Enlivex Receives Notice of Allowance for Chinese Patent Application Covering the Use of Allocetra in Patients with Osteoarthritis
Globenewswire· 2025-03-17 12:00
Nes-Ziona, Israel, March 17, 2025 (GLOBE NEWSWIRE) -- Enlivex Therapeutics Ltd. (Nasdaq: ENLV, the “Company”), a clinical-stage macrophage reprogramming immunotherapy company, today announced that the China National Intellectual Property Administration (CNIPA) issued a notice of allowance for patent application number 2020800620493. Once issued, the resulting patent will provide Enlivex with added intellectual property protection in China through at least 2040 with claims covering methods of using Allocetra ...