NeoGenomics (NasdaqCM:NEO) FY Conference November 19, 2025 02:00 PM ET Company ParticipantsJeff Sherman - CFOWarren Stone - COOTony Zook - CEOConference Call ParticipantsMason Carrico - AnalystMason CarricoAll right. Welcome to day two of the Stephens Conference. I'm Mason Carrico. I'm the diagnostics and medtech analyst here at Stephens. Excited to have NeoGenomics joining us today. We've got Tony Zook, CEO, Jeff Sherman, CFO, and Warren Stone, COO. Thank you, guys, for joining us.Tony ZookThanks for havin ...

Financial Data and Key Metrics Changes - Total revenue for Q3 2025 was $188 million, representing a year-over-year growth of 12% [11][18] - Clinical revenue increased by 18% year-over-year, while non-clinical revenue declined by 27% [18] - Adjusted EBITDA was $12.2 million, marking the ninth consecutive quarter of positive earnings [21] - Average revenue per clinical test (AUP) increased by 3% year-over-year, with a sequential increase of 4% from Q2 [19][20] Business Line Data and Key Metrics Changes - Clinical business revenue grew by 15% excluding the Pathline acquisition, driven by effective execution of the commercial strategy [11] - NGS revenue grew by 24% year-over-year, accounting for 33% of total clinical revenue year-to-date [19] - Non-clinical revenue accounted for less than 9% of total revenue in Q3, consistent with expectations [12] Market Data and Key Metrics Changes - The therapy selection and MRD markets represent over $40 billion of addressable market opportunity, both growing rapidly [10] - MRD cancer surveillance and monitoring is estimated to be a $30 billion market, growing at a 30% CAGR with less than 10% market penetration [14] Company Strategy and Development Direction - The company is focused on advancing NGS and MRD long-term growth initiatives, including the launch of the RaDaR ST MRD assay [6][10] - The acquisition of Pathline enhances the company's presence in the Northeast, allowing for faster turnaround times and a broader test menu [8] - The company aims to consolidate send-out testing to simplify operational workflows and improve patient experience [9] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about significant opportunities in cancer testing, particularly in community settings where 80% of cancer care is delivered [7] - The company anticipates continued strong clinical performance and growth in NGS and MRD markets [17] - Full-year consolidated revenue guidance is revised to $720 million-$726 million, representing growth of 9%-10% over 2024 [22][23] Other Important Information - The company received a favorable court ruling regarding the RaDaR ST MRD assay, allowing for broader commercialization [12][13] - Cash flow from operations was positive at $9 million, with total cash at $164 million [21] Q&A Session Summary Question: How comfortable is the company with the guidance and the latest on PanTracer LBx? - Management believes they are in a good position to meet Q4 expectations and confirmed that PanTracer LBx does not need approval from MolDX to meet guidance [26][27] Question: What are the growth drivers expected for 2026? - Growth drivers for 2026 are expected to be similar to 2025, with strong clinical performance and ongoing NGS growth [31] Question: Where is the company seeing the most wins on the customer side for NGS? - Most growth is coming from community oncology practices, with strong performance from the PanTracer family of products [38] Question: What is the expected impact of the LIMS rollout? - The LIMS project is expected to deliver operational efficiencies starting in 2026, with significant benefits in 2027 and beyond [42][44] Question: How is the company addressing the challenges in the pharma business? - The company is focusing on execution excellence and leveraging new products like RaDaR and PanTracer LBx to improve relevance in the pharma space [54][56]

Financial Data and Key Metrics Changes - Total revenue for Q3 2025 was $188 million, representing a year-over-year growth of 12% [11][18] - Clinical revenue increased by 18% year-over-year, while non-clinical revenue declined by 27% [18] - Adjusted EBITDA was $12.2 million, marking the ninth consecutive quarter of positive earnings [18] - Average revenue per clinical test (AUP) increased by 3% year-over-year, with a sequential increase of $15 [19][20] Business Line Data and Key Metrics Changes - Clinical business revenue growth was 15% excluding the Pathline acquisition, driven by effective execution of the commercial strategy [11] - NGS revenue grew by 24% year-over-year, accounting for 33% of total clinical revenue year-to-date [19] - Total test volumes increased by 15% in Q3, with a same-store revenue growth of 15% [18][19] Market Data and Key Metrics Changes - The therapy selection and MRD markets represent over $40 billion of addressable market opportunity, both growing rapidly [10] - MRD cancer surveillance and monitoring is estimated to be a $30 billion addressable market, growing at a 30% CAGR [14] Company Strategy and Development Direction - The company is focused on advancing NGS and MRD long-term growth initiatives, including the launch of the Radar ST MRD assay [6][10] - The acquisition of Pathline enhances the company's presence in the Northeast, allowing for faster turnaround times and a broader test menu [8] - The company aims to consolidate send-out testing to simplify operational workflows and improve patient experience [9] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about significant opportunities in cancer testing, particularly in community settings where 80% of cancer care is delivered [7] - The company anticipates continued strong clinical performance and growth in NGS and MRD markets [17] - Full-year consolidated revenue guidance is revised to a range of $720 to $726 million, representing growth of 9% to 10% over 2024 [22][23] Other Important Information - The company has received Moldex approval for Radar ST in subsets of head and neck and breast cancer, preparing for a robust launch in Q1 2026 [13] - The LIMS project is expected to deliver operational efficiencies starting in 2026 and 2027 [22][44] Q&A Session Summary Question: How comfortable is the company with the guidance and the latest on PanTracer LBx? - Management believes they are in a good position to meet Q4 expectations and confirmed that PanTracer LBx does not require approval to meet guidance [27][32] Question: What is the growth outlook for MRD and its reimbursement? - Management expects MRD to contribute to revenue in 2026, with a slow revenue build anticipated [33][34] Question: Where is the company seeing wins in the NGS business? - Most growth is coming from community oncology practices, with strong performance from the PanTracer family of products [38][41] Question: What are the expected benefits from the LIMS rollout? - The LIMS system will simplify operations, improve turnaround times, and enhance customer experience, with benefits expected to materialize in 2026 and beyond [42][46] Question: How is the company addressing the challenges in the pharma business? - The company is focusing on execution excellence and leveraging new products like Radar ST and PanTracer LBx to regain traction in the pharma segment [54][56]

Financial Data and Key Metrics Changes - In Q2 2025, the company reported revenue of approximately $1,060 million, reflecting a year-over-year decline of about 3% on both constant currency and reported basis [20][21] - Non-GAAP operating margin was 23.8%, an increase of 160 basis points year-over-year, while non-GAAP EPS was $1.19, growing 9% year-over-year and exceeding guidance [5][28][29] - Non-GAAP gross margin was 69.4%, stable year-over-year, with a favorable product mix contributing to improved performance [27] Business Line Data and Key Metrics Changes - Sequencing consumables revenue was approximately flat year-over-year at $740 million, with high throughput consumables showing over 10% sequential growth [21][22] - The transition to the NovaSeq X platform is progressing, with over 80% of sequencing volumes for research customers already transitioned, and clinical customers at approximately 55% [22] - Sequencing instruments revenue was down approximately 18% year-over-year, primarily due to budget constraints from research customers [24] Market Data and Key Metrics Changes - Clinical markets now account for roughly 60% of total sequencing consumables, driven by comprehensive genomic profiling and sequencing-intensive applications [5][21] - Greater China revenue was $63 million, slightly ahead of expectations but down $12 million from 2024, with ongoing discussions with regulators regarding export restrictions [20][32] Company Strategy and Development Direction - The company aims for high single-digit revenue growth and to expand non-GAAP operating margin to 26% by 2027, focusing on growing the core sequencing business and expanding services [9][31] - The acquisition of Somologic for $350 million is expected to enhance the company's capabilities in proteomics, integrating it into their multiomics strategy [30][12] Management's Comments on Operating Environment and Future Outlook - Management expressed caution for the second half of 2025 due to ongoing funding uncertainties in the U.S. research market, despite raising guidance for total company revenue growth [16][17] - The clinical segment is expected to continue driving growth, with significant opportunities in oncology and genetic disease testing [80] Other Important Information - The company repurchased approximately 4.5 million shares for $380 million, with plans to continue share repurchases throughout the year [29][30] - The company ended the quarter with approximately $1,160 million in cash and equivalents, maintaining a gross leverage of approximately 1.7x [30] Q&A Session Summary Question: Guidance change and its components - The guidance increase was attributed to FX and increased expectations for consumables, while instrumentation expectations were reduced due to research market constraints [40][44] Question: Customer behavior in anticipation of competition - The company focuses on customer engagement and innovation to remain competitive, with ongoing efforts to understand customer needs [48][50] Question: Pull forward in customer orders - No significant pull forward was observed in Q2, with a normal quarter reported; however, increased backlog was noted for future orders [56][57] Question: Clinical customer spending patterns - Clinical customers are expected to continue investing in expanding their portfolios, with a gradual transition to the NovaSeq X platform [78][82] Question: Trajectory of X placements - The company anticipates continued placements of NovaSeq X instruments, with expectations of 50-60 placements per quarter [90]

Financial Data and Key Metrics Changes - The company reported revenues of $168 million for Q1 2025, an increase of 8% compared to the prior year, aligning with the previous guidance of 8% to 10% growth [24][29] - Adjusted EBITDA improved by 102% year-over-year to $7 million, marking the seventh consecutive quarter of positive adjusted EBITDA [24][10] - Total clinical revenue increased by $15 million or 11.3% in the quarter, while non-clinical revenue declined by $3.4 million or 15.8% [25][26] Business Line Data and Key Metrics Changes - Clinical testing volumes grew by 8% year-over-year, with NGS (Next Generation Sequencing) revenue growth of 18% [11][24] - Five new NGS products launched accounted for 22% of total clinical revenue in Q1 [11][12] - The company expects to achieve 25% annual growth in NGS, supported by an expanded sales force and upcoming product launches [12][13] Market Data and Key Metrics Changes - The NGS market is projected to grow at an annual rate of 10% to 15%, with the company aiming to grow above this rate [11] - The non-clinical business, which includes pharma, is expected to decline this year due to macroeconomic factors affecting R&D spending [15][27] Company Strategy and Development Direction - The company plans to focus on innovation through R&D, business development, and commercialization of new products to enhance patient care options [6][7] - The acquisition of Pathline is expected to accelerate growth and establish a local presence in the Northeast, contributing $12 million to $14 million in revenue for 2025 [8][29] - The company aims to leverage its strong position in community oncology and enhance its test offerings to drive incremental business [7][13] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the company's strong performance and the potential for growth in the community oncology market [36][40] - There are anticipated headwinds in the pharma sector, but clinical revenue growth is expected to offset these challenges [27][45] - The company is focused on integrating Pathline and optimizing operations to realize synergies in the second half of the year [29][30] Other Important Information - The company ended Q1 with cash and marketable securities of $358 million, a decrease of 7% year-over-year, and expects to maintain sufficient liquidity for investments [28][29] - The company is committed to increasing R&D investments to drive future product innovation [27][31] Q&A Session Summary Question: Can you discuss the last thirty days at the helm and any areas needing attention? - Management confirmed strong performance and positive interactions with the team, noting no surprises but areas for continued focus [36][39] Question: Can you unpack the NGS products driving clinical revenue? - Several new products contribute significantly, with a focus on community oncology, and investments in sales resources align with product launches [40][42] Question: What are the expectations for the pharma business this year? - The pharma segment is expected to decline similarly to last year, but clinical revenue growth will help offset this [45][46] Question: How will the Pathline acquisition impact revenue and integration? - Pathline is expected to contribute to revenue growth in the future, with integration efforts ongoing [29][30] Question: What is the timeline for the next-gen MRD product? - The timeline for the next-gen MRD product is set for 2026, with opportunities for acceleration through partnerships [66][67] Question: How will the sales force maturity impact revenue? - The sales force is expected to reach full productivity in 6 to 9 months, with leverage anticipated in the second half of the year [88][91]

Financial Data and Key Metrics Changes - The company reported revenues of $168 million for Q1 2025, an increase of 8% year-over-year, and adjusted EBITDA of $7.1 million, reflecting over 100% improvement compared to the previous year [10][24][30] - Clinical testing volumes increased by 8% year-over-year, with a 3% increase in revenue per test [10][24] - Adjusted gross margins improved by 146 basis points to 47%, with adjusted gross profits up 11% to $79 million [24] Business Line Data and Key Metrics Changes - Clinical revenue grew by $15 million or 11.3% in Q1 2025, while non-clinical revenue declined by $3.4 million or 15.8% [25][26] - Next Generation Sequencing (NGS) revenue grew by 18%, with five new NGS products launched that accounted for 22% of total clinical revenue [12][24] Market Data and Key Metrics Changes - The NGS market is estimated to grow at an annual rate of 10% to 15%, with the company expecting to grow above this rate [12] - The non-clinical business, which includes pharma, is expected to decline this year due to macroeconomic factors affecting R&D spending [17][26] Company Strategy and Development Direction - The company aims to enhance its oncology solutions by expanding its test menu and focusing on community oncology settings, where 80% of cancer patients are treated [9][10] - The acquisition of Pathline is expected to accelerate growth and improve market presence in the Northeast [9][10][30] - The company plans to invest more in innovation through R&D and commercialization of new products [8][10] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the company's strong performance and the potential for growth in clinical revenue, despite headwinds in the pharma sector [39][46] - The company anticipates that the integration of Pathline will yield positive results in 2026 and beyond, despite short-term challenges [26][30] Other Important Information - The company ended Q1 2025 with cash and marketable securities of $358 million, a decrease of 7% year-over-year [29] - The company expects to pay off its convertible notes due in May 2025 using existing cash and marketable securities [29] Q&A Session Summary Question: Can you discuss the last thirty days at the helm and any areas needing attention? - Management confirmed strong performance and positive interactions with the team, with no unexpected surprises [39] Question: Can you elaborate on the NGS products driving clinical revenue? - Several new products contribute to the 22% of clinical revenue, with a focus on community oncology [41] Question: What are the expectations for the pharma business this year? - The pharma business is expected to decline similarly to last year, but clinical revenue growth is anticipated to offset this [46] Question: How is the company planning to manage cash flow and investments? - The company expects to produce positive free cash flow in 2026 and has sufficient liquidity for investments [56] Question: What is the timeline for the PANTRASER liquid biopsy launch? - The launch is expected to simplify the ordering process and drive concurrent testing, particularly for lung cancer [61] Question: What are the expectations for average revenue per test moving forward? - The average revenue per test may be impacted by the addition of Pathline, but progress is expected on a modality basis [77] Question: How long does it take for the sales force to reach full productivity? - Typically, it takes six to nine months for new sales personnel to reach full productivity [86]