Pathogenic Variant

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🚨David Friedberg: AI is starting to identify and solve problems on its own
All-In Podcast· 2025-08-02 16:54
AI Model Capabilities - AI models, like the EVO2 model from the Ark Institute, can ingest trillions of base pairs of DNA data to identify patterns [1] - These models can identify pathogenic variants in DNA, such as the BA gene variant linked to breast cancer, without prior knowledge or training [2] - AI's ability to identify patterns in DNA suggests potential for uncovering insights into complex phenomena in nature, society, and behavior [3] Limitations and Context - The EVO2 model lacked context for what the DNA represented, including the concept of genes and structured understanding of DNA function [2] - The model's success in identifying the pathogenic variant occurred without knowledge of pathogenic variants for cancer [3]