THE WOODLANDS, TX, Nov. 26, 2025 (GLOBE NEWSWIRE) -- Autonomix Medical, Inc. (NASDAQ: AMIX) (“Autonomix” or the “Company”), a medical device company dedicated to advancing precision nerve-targeted treatments, today announced the next CEO Corner segment has been published on the Company’s website. For the segment, Brad Hauser, President and CEO of Autonomix, discussed two key areas that are shaping the Company’s path forward: protecting the strength of its platform through intellectual property, and explorin ...

Core Insights - Autonomix Medical, Inc. will present at the TCT 2025 Annual Scientific Conference, showcasing its innovative nerve-targeted treatment technology [1][2] - The presentations will focus on the initial phase results of a clinical study aimed at alleviating pain in pancreatic cancer patients through transvascular energy delivery [2] Company Overview - Autonomix is a medical device company dedicated to advancing technologies for diagnosing and treating diseases related to the nervous system [4] - The company's platform technology includes a catheter-based microchip sensing array designed to detect and differentiate neural signals with high sensitivity [4][5] - Initial development efforts are concentrated on pain management, particularly for pancreatic cancer, which currently lacks effective treatment options [5] Conference Details - TCT 2025 is a four-day educational conference focused on interventional cardiovascular medicine, taking place from October 25-28, 2025, in San Francisco [3] - The conference is organized by the Cardiovascular Research Foundation and has grown significantly since its inception in 1988, now attracting thousands of attendees [3]

Core Viewpoint - Autonomix Medical, Inc. has initiated a Good Laboratory Practice (GLP) preclinical study for its Sensing and RF Ablation System aimed at treating pancreatic cancer pain, marking a significant step towards regulatory approval and potential clinical trials in the U.S. by 2026 [1][2][3] Company Overview - Autonomix is focused on advancing innovative medical technologies for diagnosing and treating diseases related to the nervous system, utilizing a first-in-class platform technology that includes a catheter-based microchip sensing array [6][7] - The company's technology aims to provide transvascular diagnosis and treatment of peripheral nervous system diseases, with initial development targeting pain management in pancreatic cancer [7] Regulatory Pathway - The GLP study is essential for ensuring the reliability and integrity of Autonomix's devices, which is a prerequisite for submitting data to the FDA for Investigational Device Exemption (IDE) clinical trials [2] - The company is on track to file its IDE application, with plans to commence clinical studies in the following year if approved [3] Technological Potential - Autonomix's technology has the potential to address multiple high-need therapeutic areas, including cardiology, resistant hypertension, interventional pain management, and gastrointestinal disorders [4][6] - The platform is designed to tackle a wide spectrum of diseases, indicating a broad market opportunity for the company [7]

Core Insights - Autonomix Medical, Inc. has reported long-term data indicating a nearly 66% reduction in pain for patients with severe pancreatic cancer pain, with a mean reduction of 5.08 on the VAS pain scale [1][7] - 100% of responders were opioid-free at the 3-month follow-up, highlighting the potential of the technology as a non-opioid alternative for pain management [2][7] - The company is expanding its proof-of-concept studies to include additional visceral cancers, indicating a broader market opportunity [3][4] Group 1: Study Results - The PoC 1 study demonstrated statistically significant pain relief as early as 24 hours post-procedure, with sustained relief lasting up to five months [3][9] - Responding patients reported a mean 76.5% improvement in global health and a 51.5% improvement in functional ability at 7 days post-procedure [7][9] - The study enrolled 20 patients, with 19 treated successfully, and showed a strong safety profile with no serious adverse events related to the procedure [11][9] Group 2: Technology and Market Potential - Autonomix's technology is a platform that could address various indications, including cardiology and chronic pain management, beyond just cancer pain [4][12] - The follow-on PoC 2 phase aims to evaluate pain management for additional visceral cancers, expanding the potential addressable market significantly [3][4] - The company's catheter-based microchip sensing array technology is designed to detect and differentiate neural signals, which may enhance treatment efficacy [10][12]

Core Viewpoint - Autonomix Medical, Inc. has announced agreements for the immediate exercise of existing warrants, allowing the purchase of up to 1,477,596 shares of common stock at a reduced exercise price of $1.723 per share, expected to generate approximately $2.5 million in gross proceeds [1][4]. Group 1: Warrant Exercise and Financial Details - The company has entered into agreements with certain warrant holders for the immediate exercise of outstanding warrants, which were originally issued in November 2024 [1]. - The gross proceeds from the exercise of these warrants are anticipated to be around $2.5 million before placement agent fees [1]. - New unregistered warrants will be issued for the immediate exercise, allowing the purchase of the same number of shares at the same exercise price of $1.723 per share, valid for five and a half years [3]. Group 2: Transaction Closing and Use of Proceeds - The transaction is expected to close on or about July 23, 2025, pending customary closing conditions [4]. - The net proceeds from this offering will be utilized for working capital and general corporate purposes [4]. Group 3: Company Overview and Technology - Autonomix Medical is focused on advancing innovative technologies for diagnosing and treating diseases of the nervous system, utilizing a catheter-based microchip sensing array [7]. - The company is initially developing its technology for pain treatment, particularly targeting pancreatic cancer, and aims to address various conditions across a wide disease spectrum [8].