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Selective oestrogen receptor degrader
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Positive phase III results show Roche’s giredestrant significantly improved progression-free survival in ER-positive advanced breast cancer
Globenewswire· 2025-09-22 05:00
evERA met its co-primary endpoints; giredestrant plus everolimus demonstrated significant benefit in ITT and ESR1-mutated populations in post-CDK inhibitor setting, compared with standard of care plus everolimus The all-oral combination was well tolerated and adverse events were consistent with the known safety profiles of the individual study treatments; no new safety signals were observed evERA is the first positive head-to-head phase III trial investigating an all-oral selective oestrogen receptor deg ...
Positive phase III results show Roche's giredestrant significantly improved progression-free survival in ER-positive advanced breast cancer
Globenewswire· 2025-09-22 05:00
evERA met its co-primary endpoints; giredestrant plus everolimus demonstrated significant benefit in ITT and ESR1-mutated populations in post-CDK inhibitor setting, compared with standard of care plus everolimus The all-oral combination was well tolerated and adverse events were consistent with the known safety profiles of the individual study treatments; no new safety signals were observed evERA is the first positive head-to-head phase III trial investigating an all-oral selective oestrogen receptor deg ...