Cantor Global Healthcare Conference Format: One-on-one meetings Date: September 3-5, 2025 ROCKVILLE, Md., Aug. 21, 2025 (GLOBE NEWSWIRE) -- I-Mab (NASDAQ: IMAB) (the "Company"), a U.S.-based, global biotech company, focused on the development of precision immuno-oncology agents for the treatment of cancer, today announced that I-Mab's management team will participate in the following upcoming investor conferences in September, 2025: H.C. Wainwright 27 Annual Global Investment Conference Conference details a ...

Extensive experience from senior oncology research roles at Roche, MorphoSys, Boehringer Ingelheim and most recently CSO at SOTIO Biotech ZURICH-SCHLIEREN, Switzerland and CONCORD, Mass., Aug. 21, 2025 (GLOBE NEWSWIRE) -- Ad hoc announcement pursuant to Art. 53 LR Molecular Partners AG (SIX: MOLN; NASDAQ: MOLN), a clinical-stage biotech company developing a new class of custom-built protein drugs known as DARPin therapeutics ("Molecular Partners" or the "Company"), today announced the appointment of Martin ...

Financial Data and Key Metrics Changes - Group revenues increased by 63% year on year, reaching $390 million, driven by growth in Elucix and the addition of third-party revenue from RLS [9][10] - Precision medicine revenues rose by 30% year on year, with EBITDA improving by 24% [9] - Gross margins in the precision medicine business remained stable at 64%, while the group's overall gross margin was 53% [9][10] Business Line Data and Key Metrics Changes - The precision medicine business saw a revenue increase of 29%, with EBITDA improving by $20 million year on year [14] - RLS contributed $79 million in third-party sales, with a gross margin of 7% [10][16] - Selling and marketing expenses increased to 13% of revenue from 10% last year, reflecting preparations for product and geographic expansion [12] Market Data and Key Metrics Changes - Elucix continues to deliver strong growth, with revenues up 25% year on year and dose volumes up 7% [43] - The global rollout of Elucix is progressing well, with marketing authorizations secured in over 23 countries [45] - The company is focusing on expanding into key markets such as France, Germany, Italy, Spain, China, and Japan [45] Company Strategy and Development Direction - The company is transitioning from a single product to a multi-product, multi-region organization, with a focus on long-term growth rather than short-term EPS optimization [21][25] - Strategic investments have been made in R&D, commercial performance, M&A opportunities, and supply chain resilience [19] - The acquisition of RLS is seen as a critical move to enhance U.S. presence and improve distribution capabilities [30] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to navigate the current operating environment and emphasized the importance of strategic investments for long-term growth [21][39] - The company is focused on building long-term asset value and is committed to delivering value for shareholders and patients [75] - Management acknowledged the SEC inquiry but clarified that it has no impact on the commercial portfolio or pipeline development [39] Other Important Information - The company has made significant investments in its global manufacturing infrastructure, with cash on hand at $27 million [10][18] - R&D investments increased by 47% year on year, reflecting a commitment to advancing the therapeutic pipeline [10][12] Q&A Session Summary Question: Outlook for gross margins and impact of PSMA pricing changes - Management noted that Elucix's gross margin remained consistent at 64% and that RLS's gross margin is expected to improve as more Elucix products are integrated [80][81] Question: Guidance and growth of Elucix moving forward - Management confirmed that July 1 marked the end of pass-through status for one product, but they reported 7% growth quarter on quarter, indicating strong performance despite market challenges [86][87] Question: Launch readiness for Zurkayx - Management indicated that specific details about the launch readiness for Zurkayx could not be disclosed at this time [95]

Summary of Conference Call Records Company Overview GeoVax Labs - **Industry**: Biotechnology - **Focus**: Developing vaccines for infectious diseases and therapies for solid tumor cancers, including COVID-19 and MPOXX (monkeypox) [1][2] Bitfufu Inc - **Industry**: Cryptocurrency Mining - **Focus**: Bitcoin mining and mining services, including cloud mining and self-mining operations [24][25] Key Points from GeoVax Labs Business Goals and Focus - GeoVax is a clinical-stage biotech company targeting unserved or underserved populations for vaccine development [4] - The company has a strong patent portfolio, recently announcing a new broad patent for its multi-antigen COVID-19 vaccine [3] Market Opportunities - The global market opportunity for GeoMVA (MPOXX vaccine) exceeds $11 billion [4] - Over 40 million adults in the U.S. and 400 million worldwide have weakened immune systems that do not respond to current vaccines [5][6] Alignment with Government Initiatives - GeoVax aligns with bipartisan efforts for diverse vaccine development and long-term safety, emphasizing transparency in the vaccine industry [7][11] Capital Development Strategy - The company targets raising approximately $30 million annually through equity sales and non-dilutive funding [13][15] - Last year, GeoVax raised over $25 million, enabling continued progress on its programs [14] Competitive Landscape - Bavarian Nordic is currently the only supplier for the Impox MVA vaccine, and its acquisition by a private equity firm raises concerns about monopoly and pricing [18][19] - GeoVax plans to initiate a Phase 3 trial for its GeoMVA vaccine in the second half of next year, aiming for revenue generation within three years [20][21] Key Points from Bitfufu Inc Company Performance - Bitfufu reported a substantial increase in cloud mining revenue, with over half coming from new customers, indicating strong demand [30] - The company holds 1,784 Bitcoin on its balance sheet and has a mining capacity of 38.6 exahash [26][30] Strategic Developments - Bitfufu is acquiring more data centers to reduce leased capacity, which helps lower operational costs [27] - The company has seen a year-over-year decline in self-mining revenue due to the Bitcoin halving event [33] Financial Performance - Bitfufu reported EBITDA of $60.7 million, a significant increase from $8.3 million year-over-year [35] - The company has maintained profitability since its inception, distinguishing itself from many peers in the mining space [36] Growth Strategy - The company is focusing on vertical integration and horizontal innovation, with plans to expand its capacity to over a gigawatt by 2026 [37] - Bitfufu's cloud mining business accounted for 80% of its revenue in the second quarter, reflecting strong demand [38] Institutional Interest - There is a growing interest from institutional investors, particularly in using cloud mining as a corporate treasury strategy [43][44] Additional Important Insights - GeoVax's approach to vaccine development emphasizes expedited registration pathways and collaborations to mitigate risks [4] - Bitfufu's strategic framework with Bitmain allows access to a significant number of mining rigs, enhancing its competitive position [34] - Both companies are positioned to capitalize on their respective market opportunities, with GeoVax focusing on vaccine development and Bitfufu on expanding its mining capabilities and services [21][41]

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On Wednesday, William Blair initiated coverage on Kyverna Therapeutics Inc. KYTX, a small-cap biotechnology company focused on cell therapies for autoimmune disorders. Kyverna's lead CAR T-cell therapy candidate, KYV-101, is advancing through late-stage clinical development with registrational trials for stiff person syndrome and myasthenia gravis, and two ongoing multi-center Phase 1/2 trials for patients with lupus nephritis. Topline data for the registrational Phase 2 trial of KYV-101 in stiff person syn ...

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Core Viewpoint - Calidi Biotherapeutics, Inc. has successfully priced a public offering to raise $6 million, indicating strong interest from both existing and new investors despite challenging market conditions [1][2]. Group 1: Offering Details - The offering consists of 1,472,764 common stock units priced at $2.00 each, and 1,528,000 pre-funded warrant units priced at $1.999 each [2]. - Each common stock unit includes one share of common stock and one Series I warrant, while each pre-funded unit includes one pre-funded warrant and one Series I warrant [2]. - The Series I warrants have an exercise price of $2.00 per share and are exercisable upon issuance, expiring five years from issuance [2]. Group 2: Underwriting and Closing - Ladenburg Thalmann & Co. Inc. is the sole book-running manager for the offering, with Laidlaw & Company (U.K.) Ltd. acting as a co-manager [3]. - The underwriters have a 45-day option to purchase an additional 450,000 shares of common stock and/or warrants at the public offering price [3]. - The offering is expected to close on or about August 21, 2025, pending customary closing conditions [3]. Group 3: Company Overview - Calidi Biotherapeutics is a clinical-stage biotechnology company focused on developing targeted therapies for delivering genetic medicines to disease sites [6]. - The company's proprietary Redtail platform utilizes an engineered enveloped oncolytic virus for systemic delivery to metastatic sites, aiming to enhance the effectiveness of virotherapy [6]. - The lead candidate from the Redtail platform is currently in IND-enabling studies, targeting non-small cell lung cancer, ovarian cancer, and other high unmet medical need tumor types [7].

Company Overview - Longeveron Inc. is a clinical stage biotechnology company focused on developing regenerative medicines to address unmet medical needs [2] - The company's lead investigational product is laromestrocel (Lomecel-B™), an allogeneic mesenchymal stem cell therapy derived from the bone marrow of young, healthy adult donors [2] - Laromestrocel has multiple potential mechanisms of action, including pro-vascular, pro-regenerative, anti-inflammatory, and tissue repair effects, with applications across various disease areas [2] Pipeline and FDA Designations - Longeveron is pursuing four pipeline indications: hypoplastic left heart syndrome (HLHS), Alzheimer's disease, Pediatric Dilated Cardiomyopathy (DCM), and Aging-related Frailty [2] - The HLHS program has received three important FDA designations: Orphan Drug designation, Fast Track designation, and Rare Pediatric Disease designation [2] - The Alzheimer's disease program has received two FDA designations: Regenerative Medicine Advanced Therapy (RMAT) designation and Fast Track designation [2] Upcoming Events - Longeveron will participate in the H.C. Wainwright 27th Annual Global Investment Conference from September 8-10, 2025, in New York City [1] - The company's presentation is scheduled for September 8, 2025, from 4:00 to 4:30 p.m. ET, with a webcast available on the company's website [1]