Core Insights - Thermo Fisher Scientific Inc. reported third-quarter 2025 adjusted earnings of $5.79 per share, surpassing the street estimate of $5.49 [1] - Quarterly sales reached $11.12 billion, reflecting a 5% year-over-year increase and exceeding the analyst consensus of $10.91 billion, with organic revenue growth of 3% [2] - The company expressed confidence in achieving its 2025 objectives, highlighting strong operational performance and effective management strategies [3] Financial Performance - Life Sciences Solutions sales increased by 8.4% to $2.59 billion, while Analytical Instruments sales rose by 4.7% to $1.89 billion [4] - Specialty Diagnostics revenues reached $1.17 billion, up 4%, and Laboratory Products and Biopharma Services sales increased by 4% to $5.97 billion [4] Guidance - For 2025, Thermo Fisher expects sales between $44.1 billion and $44.5 billion, an increase from the previous guidance of $43.6 billion to $44.2 billion, and above the consensus of $43.99 billion [5] - The company anticipates annual profit per share of $22.60 to $22.86, compared to prior guidance of $22.22 to $22.84 and a consensus of $22.50 [5] - Annual revenue from China is expected to decline in the mid- to high-single digits [5] Analyst Commentary - Analysts noted that revenue exceeded expectations due to strong performance in Life Science Solutions and Analytical Instruments, with adjusted EBIT coming in 7% above targets [6] - The third-quarter results support the view that the worst is over for the tools sector, with future guidance expected to clarify recovery rates [7]

Core Insights - Polen Capital's "Polen Focus Growth Strategy" reported a gross return of 3.34% and a net return of 3.14% for Q3 2025, underperforming the Russell 1000 Growth Index at 10.51% and the S&P 500 Index at 8.12% [1] - The equity market's strong performance was attributed to enthusiasm for generative AI and strength in the semiconductor sector, alongside positive economic surprises and better-than-expected corporate earnings [1] Company-Specific Insights - Thermo Fisher Scientific Inc. (NYSE:TMO) was highlighted as a key stock, with a one-month return of 9.12% but a 52-week loss of 12.65%, closing at $524.58 per share with a market capitalization of $198.088 billion on October 13, 2025 [2] - Polen Focus Growth Strategy eliminated its position in Thermo Fisher Scientific to fund the purchase of Uber, citing ongoing macro, policy, and funding headwinds that are expected to persist [3] - Thermo Fisher Scientific's revenue grew 3% to $10.85 billion in Q2, and it ranked 26th among the 30 most popular stocks among hedge funds, with 117 hedge fund portfolios holding its stock at the end of Q2 [4]

Core Insights - Waters Corporation has launched the Waters Xevo Charge Detection Mass Spectrometer (CDMS), which offers advanced measurement capabilities for large biomolecules essential for next-generation therapeutics and structural biology [2][4] - The Xevo CDMS addresses limitations in existing analytical tools, providing direct mass measurement for molecules exceeding 150 MDa, thus enabling analysis of complex drug modalities [2][4] Product Features - The Xevo CDMS allows for the analysis of viral vector capsids using up to 100-fold less sample volume compared to current methods, delivering results in under ten minutes [3][4] - It enables real-time characterization of gene therapies during development, enhancing the safety and efficacy of advanced therapies [4][6] - The system utilizes the Electrostatic Linear Ion Trap (ELIT) technology for direct measurement of individual ions, developed in collaboration with Indiana University [5][10] Strategic Importance - The introduction of the Xevo CDMS is part of Waters Corporation's strategic investment in large molecules, which is crucial for advancing therapeutic breakthroughs [4][5] - The technology is expected to accelerate the development of genetic medicines and improve accessibility to life-changing therapies for patients [4][5] Market Position - Waters Corporation is recognized as a global leader in analytical instruments and technologies, serving various sectors including life sciences, materials, food, and environmental sciences for over 65 years [7][8]

Core Points - Waters Corporation (NYSE: WAT) will hold its Q3 2025 financial results conference call on November 4th, 2025 at 8:00 a.m. Eastern Time [1] - A live webcast of the presentation will be available on Waters Investor Relations website, with a replay accessible until December 2nd, 2025 [1] - Waters Corporation is a global leader in analytical instruments, separations technologies, and software, serving various sectors for over 65 years [1] - The company operates in over 100 countries with more than 7,600 employees, focusing on the efficacy of medicines, safety of food, purity of water, and sustainability of products [1] Financial Performance - The company reported its financial results for the second quarter of 2025, with sales amounting to $771 million [3]

Financial Data and Key Metrics Changes - The company reported a strong top-line growth of 6% core revenue, with significant contributions from pharma and CAM [3][4] - The guidance for revenue was raised by 25%, driven by broad-based growth, particularly in pharma and CDMO [3][4] - Gross margins were impacted by tariffs, leading to a 200 basis point decline year-on-year, but a sequential improvement of approximately 230 basis points is expected in Q4 [11][12][15] Business Line Data and Key Metrics Changes - Pharma QAQC grew mid-teens in Europe, driven by consolidation of supply chains and new greenfield sites [5][29] - The Infinity Tree product line saw a 15% growth, indicating a steady replacement cycle [6][19] - CDMO experienced a remarkable 20% growth, with bookings extending into 2026 [7][35] Market Data and Key Metrics Changes - The A and G segment showed stability with mid- to high single-digit growth in Europe and 20% growth in China, although the U.S. market faced challenges [24][26] - In China, pharma and biopharma markets are experiencing high innovation rates, with a significant increase in out-licensing [48][50] - The CAM segment reported 10% growth in both chemicals and advanced materials, driven by investments in semiconductors and sustainability initiatives [42][44] Company Strategy and Development Direction - The company is focused on innovation and productivity improvements, particularly in the CDMO and pharma sectors, which are expected to drive growth [30][80] - There is a strategic emphasis on maintaining close ties with the Chinese market, leveraging local manufacturing capabilities [52][56] - The company is disciplined in M&A activities, seeking high-quality targets that align with its growth strategy [75][76] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in a gradual improvement in the operating environment, despite geopolitical uncertainties and tariff impacts [12][74] - The company anticipates a strong performance in 2026, supported by new capacity coming online and a favorable order book [36][37] - There is a cautious but positive outlook for next year, with expectations of mid-single-digit growth [74] Other Important Information - The company has seen a significant increase in variable pay due to improved business performance, impacting margins [15] - The PFAS market is expected to rebound after a temporary slowdown due to regulatory uncertainties, with long-term growth drivers remaining intact [68][70][71] Q&A Session Summary Question: What are the expectations for growth in 2026? - Management is optimistic about growth in 2026, with new capacity coming online and a strong order book supporting this outlook [36][37] Question: How is the company addressing tariff impacts? - The company has implemented mitigations for tariff costs and expects these to decrease by 2026, turning from a headwind to a tailwind [12][15] Question: What is the outlook for the PFAS market? - The PFAS market is expected to recover, with regulations remaining stable and an increase in testing driven by litigation [70][71]

Core Viewpoint - 908 Devices reported strong revenue growth in Q2 2025, with revenue reaching $13.0 million, exceeding Wall Street expectations, but faced challenges in profitability and margin management [1][5][14] Financial Performance - Revenue (GAAP) increased by 14% year-over-year, surpassing estimates by 6.8% [1][5] - GAAP earnings per share were reported at $(0.36), a decline of 63.6% compared to the previous year [2][8] - Adjusted gross margin decreased to 56% from 59% year-over-year, while GAAP gross margin fell to 49% from 54% [2][7] - Operating expenses rose by 46% to $21.5 million compared to Q2 2024 [7] - Net loss from continuing operations widened to $12.9 million from $7.6 million in Q2 2024 [8][9] Business Overview and Strategy - 908 Devices specializes in portable chemical analysis instruments, targeting sectors such as public safety, law enforcement, military, and pharmaceuticals [3] - The growth strategy includes innovation in device miniaturization, acquisitions to enhance technology capabilities, and expanding the customer base [4][10] - Recurring revenue accounted for 36% of total revenue in Q2 2025, reflecting a 28% increase to $4.7 million [6] Operational Highlights - The company placed 164 new devices, increasing the global installed base to 3,336, a 27% year-over-year growth [5][12] - The launch of the VipIR handheld chemical analyzer exemplifies the company's focus on expanding its product offerings [10] - Manufacturing consolidation efforts are expected to streamline costs and improve efficiency, although immediate benefits were not reflected in quarterly margins [11][13] Outlook and Future Prospects - Management raised full-year 2025 revenue guidance to $54 million–$56 million, indicating a projected growth of 13–17% [14] - The company aims to achieve adjusted EBITDA break-even by Q4 2025 and become cash-flow positive in 2026 [14][15] - Opportunities for growth are seen in innovation, diversification into related technologies, and a favorable funding environment in public safety [15]

Core Insights - Waters Corporation reported second quarter 2025 sales of $771 million, reflecting a 9% increase as reported and an 8% increase in constant currency compared to $709 million in the same quarter of 2024 [1][13] - The diluted earnings per share (EPS) for the second quarter of 2025 was $2.47, up from $2.40 in the second quarter of 2024, while non-GAAP EPS grew 12% to $2.95 from $2.63 [2][13] - The company is raising its full-year 2025 sales growth guidance to a range of +5.5% to +7.5% in constant currency and +5.0% to +7.0% reported [4][5] Financial Performance - The company achieved a net income of $147.1 million for the second quarter of 2025, compared to $142.7 million in the same quarter of 2024 [18] - Recurring revenue grew 11% in constant currency, with service growth at 9% and double-digit growth in chemistry [13] - The company reported operating income of $188.2 million for the second quarter of 2025, slightly down from $189.1 million in the same quarter of 2024 [17] Market and Product Insights - Instrument sales grew mid-single digits in constant currency, driven by high-single-digit growth in liquid chromatography (LC) and mass spectrometry (MS) [13] - The pharmaceutical market grew 11% in constant currency, while the industrial market grew 6%, and academic & government declined by 3% [13] - The company noted strong instrument replacement trends, particularly among large pharmaceutical and contract development and manufacturing organization (CDMO) customers [3] Guidance and Future Outlook - For the third quarter of 2025, the company expects constant currency sales growth in the range of +5.0% to +7.0% and reported sales growth of +4.5% to +6.5% [6] - Non-GAAP EPS for the third quarter of 2025 is projected to be in the range of $3.15 to $3.25, reflecting year-over-year growth of approximately +8% to +11% [6] - The company is well-positioned for future growth, particularly through its combination with BD Biosciences & Diagnostic Solutions, which is expected to enhance its strategy in high-growth adjacencies [3]

Company Overview - Waters Corporation (NYSE:WAT) is a global leader in analytical instruments, separations technologies, and software, serving various sectors including life sciences, materials, food, and environmental sciences for over 65 years [2] - The company ensures the efficacy of medicines, safety of food, purity of water, and quality and sustainability of everyday products [2] - Waters Corporation operates in over 100 countries with a workforce of more than 7,600 employees [2] Upcoming Financial Events - Waters Corporation will hold its Q2 2025 financial results conference call on August 4th, 2025, at 8:00 a.m. Eastern Time [1] - A live webcast of the presentation will be available on the Waters Investor Relations website, with a replay accessible until at least September 2nd, 2025 [1]

Strategic Focus and Financial Improvement - The company is shifting its focus to high-growth handheld markets, aligning with trends in opioid crisis response, defense budgets, and border security[8] - The company aims to achieve positive adjusted EBITDA by Q4 2025 and become cash flow positive in 2026, driven by improved gross margins and streamlined operations[8] - The company is divesting its biopharma desktop portfolio to REPLIGEN for $70 million in cash, nearly doubling its balance sheet cash and eliminating NIH/healthcare overhang[8] - The company retains the flexibility to operate in the broader life sciences market beyond the divested bioprocessing PAT segment[9] Financial Performance and Projections - The company's revenue in 2023 was $38.2 million[11] - The company held $146 million cash at year-end 2023[11] - The company experienced a net loss of $30 million in 2023[11] - The company shipped 2,422 devices in 2023[11] - The company projects revenue between $53 million and $55 million for 2024, representing an 11% to 15% year-over-year increase[13] - The company anticipates having over 3,015 devices in the field by the end of 2024, a 25% increase from 2023[13] - The company expects to have $110 million+ cash at year-end 2025[13, 16]

Core Insights - Waters Corporation has launched the Xevo™ TQ Absolute XR Mass Spectrometer, which is positioned as the most sensitive and reliable benchtop tandem quadrupole in the market, surpassing the previous Xevo TQ Absolute model [2][4][10] Product Performance - The Xevo TQ Absolute XR offers up to a six-fold increase in performance robustness and unmatched sensitivity, significantly reducing downtime and enhancing operational efficiency [3][5][9] - The system is designed for high-throughput applications, particularly in pharmaceutical companies and contract testing organizations, addressing the complex needs of these sectors [2][6] Environmental Efficiency - The new mass spectrometer uses up to 50% less power and nitrogen gas, produces 50% less heat, and occupies up to 50% less bench space compared to other high-performing tandem or triple quadrupoles, making it environmentally friendly [6][9] Technological Innovations - The introduction of the StepWave XR Ion Guide minimizes the risk of unplanned downtime while maintaining high sensitivity and precision for complex sample types [7][10] - The design allows for industry-leading quantitation of negatively ionizing compounds, such as PFAS, benefiting bioanalytical, food safety, and environmental testing laboratories [10] Market Availability - The Xevo TQ Absolute XR Mass Spectrometer is currently available for order [11]