Summary of Niagen Bioscience Conference Call Company Overview - Niagen Bioscience is focused on the development and commercialization of nicotinamide riboside (Niagen), a molecule that elevates NAD levels in cells, which is crucial for energy metabolism and cellular repair [5][7][8] - The company has over 90 patents protecting its core molecule and has built a strong scientific foundation with extensive research [8][14] Core Points and Arguments - **Scientific Research and Clinical Studies**: Niagen has conducted 40 peer-reviewed clinical studies demonstrating the safety and efficacy of its product, particularly in age-related conditions [7][18][24] - **Unique Positioning**: Unlike many dietary supplement companies, Niagen is rooted in scientific research and intellectual property, which differentiates it from competitors that primarily engage in marketing [11][14][17] - **Regulatory Challenges**: The company faces strict regulations that prevent it from making health claims typically associated with drugs, which influences its marketing strategy [23][24] - **Market Strategy**: Niagen relies on word-of-mouth and expert endorsements rather than direct consumer claims to build trust and credibility [24][25] Recent Developments - **Product Launches**: The company launched the Niagen Plus line, which includes IV products and at-home injectables, generating significant media attention and interest from celebrities and influencers [34][35][40] - **Clinical Trials**: A phase three clinical study on Parkinson's disease with 400 participants is nearing completion, which could significantly impact the company's valuation and credibility in the biotech space [18][54] - **Financial Health**: Niagen is cash flow positive, has no debt, and does not require additional capital for its operations, which is atypical for biotech companies [52][54] Potential Risks and Concerns - **Market Competition**: The rise of fraudulent companies claiming to offer NAD products poses a risk to the overall market perception and could impact Niagen's reputation [27][29] - **Consumer Education**: There is a need to educate consumers about the differences between Niagen and other NAD products, particularly regarding bioavailability and efficacy [27][37] Future Outlook - **Injectable Products**: The company plans to introduce a self-injection product within the next year, tapping into the growing trend of self-administered health solutions [49][50] - **Pharmaceutical Opportunities**: Niagen is exploring drug indications beyond dietary supplements, which could enhance its market position and attract sophisticated investors [54] Conclusion - Niagen Bioscience is well-positioned in the NAD market with a strong scientific foundation, innovative products, and a clear strategy to navigate regulatory challenges while maintaining financial stability. The company's focus on research and quality sets it apart from competitors, and its future product developments could significantly expand its market reach and impact.

Core Insights - Safety Shot, Inc. is expanding its patented wellness approach into the high-growth cognitive and restorative sleep markets, focusing on scientific rigor and unique formulations [1][3] - The company aims to leverage its expertise in developing its existing product, Sure Shot, to create new nootropic and sleep aid products [3][4] Company Developments - Safety Shot is initiating research and development for new product lines targeting nootropics and sleep aids, with prototypes expected later this year [1][6] - The company emphasizes a commitment to efficacy and tangible results, with a focus on advanced technologies to create distinct advantages in the market [4][6] Market Potential - The global nootropics supplements market is valued at approximately $6.5 billion and is projected to exceed $14.9 billion by 2034, with a compound annual growth rate (CAGR) of 8.7% [5] - The sleep-related supplements market was valued at $6.8 billion in 2023, with an anticipated CAGR of 5.1%, reaching $11.8 billion by 2034 [5] Product Focus - The new nootropic product will be engineered to enhance focus, cognition, and overall brain health for daily use [7] - The sleep aid aims to improve sleep quality and duration, addressing the critical role of sleep in productivity and mental clarity, with a unique formulation not typically found in existing products [7]

Core Viewpoint - Safety Shot, Inc. is holding its Annual Shareholders' Meeting on June 12, 2025, in a virtual format, emphasizing the importance of shareholder participation and voting [1][4]. Meeting Details - The meeting will commence at 11:00 AM EDT and requires prior registration for attendance [1]. - The record date for stockholders entitled to vote is April 28, 2025 [2]. Proxy Proposals - Several key proposals will be voted on during the meeting, including: 1. Approval of the issuance of Safety Shot Shares to Yerbaé Shareholders [5]. 2. Amendment to the Safety Shot 2024 equity incentive plan to increase the number of shares reserved for issuance [5]. 3. Authorization for the issuance of promissory notes and shares related to a securities offering completed on January 20, 2025 [5]. 4. Approval for the issuance of up to 20,000,000 Safety Shot Shares to Core 4 Capital Corp. in non-public offerings [5]. 5. Granting authority for a reverse stock split within a specified range [5]. 6. Proposal for adjournment of the meeting if necessary to solicit additional proxies [5]. Voting Information - Shareholders received a Notice of Internet Availability of Proxy Materials in early May, detailing how to access the Proxy Statement and annual report [3]. - Voting can be conducted via internet, telephone, or mail, with dedicated phone numbers provided for assistance [1][3]. Company Overview - Safety Shot, Inc. specializes in wellness and dietary supplements, with its flagship product, Sure Shot, designed to lower blood alcohol content while enhancing clarity and energy [5][6]. - The company plans to expand its business-to-business sales of Sure Shot to various distributors and retailers throughout 2025 [6].

Group 1 - NYO3 launched its Ageless series, a new anti-aging product line, at international exhibitions in Europe and China, marking a strategic upgrade in the global anti-aging market [1][3] - The Ageless Aurora Skin Capsule combines European skin barrier repair technology with Korean whitening patented ingredients, targeting three core mechanisms of aging: light aging, oxidation, and collagen loss [3][5] - The product achieved significant sales success, topping Tmall International's oral beauty rankings in its first month, with sales exceeding 2 million in one hour during a live stream [5][7] Group 2 - NYO3 has partnered with Tmall International to enhance its market presence through data-driven user insights and targeted marketing, aiming to create a new consumption scenario for anti-aging products [5][7] - The Ageless product line currently includes four key products, with plans to expand to over 20 supplements addressing various health and beauty needs [5][7] - The company emphasizes user experience and results-driven commitments, such as a 90-day skin improvement program with a full refund guarantee if results are not achieved [7]

高纯度 Omega-3丨 白皮书 核心摘要： 在健康中国战略全面推进的背景下，国民健康管理意识显著提升，健康需求从 "被动治疗"向"主动预防"加 速转型。随着慢性病防控与亚健康改善成为全民健康的核心议题，膳食营养补充剂已成为全民健康管理的重 要工具，其市场发展与科学认知深化同步推进。基于这一现状，本白皮书旨在深入探讨高纯度 Omega-3 在中国居民健康管理中的作用及应用现状，加强公众对其生理功效的认知，为公众提供更加专业的营养指 导。白皮书从以下五个章节展开： 一、中国居民健康管理现状 国家政策推动全民健康管理向主动预防转型，面对慢性病年轻化与全周期防护挑战，需构建监测、干预与营 养支持体系。膳食营养补充剂通过定向支持和免疫力提升，成为公众践行主动健康管理的核心工具，助力实 现从治疗到预防的跨越。 二、膳食营养补充剂市场认知及应用表现 在国民健康管理需求升级与膳食营养补充剂市场快速发展的双轮驱动下，服用膳食营养补充剂已进阶为现代 人健康管理的核心方案。在消费者决策矩阵中，产品本身与品牌背书构成购买双引擎。但不同人群对成分需 求呈现差异化特征，折射精准健康管理趋势。 三、 Omega-3 产品与应用现状 Om ...

Core Insights - Julydeer® is a dietary supplement brand founded in 2012 in Colorado, USA, focusing on "scientific, rigorous, innovative, and safe" principles in its product development and manufacturing [1] - The brand emphasizes technological innovation and has established a comprehensive R&D and production system for dietary supplements, ensuring product safety and efficacy through various certifications [1] - The company combines traditional herbal wisdom with modern scientific research, adhering to evidence-based medicine principles in its product formulations [1] Product Range - **Liver Protector: Milk Thistle Hard Capsules** - Contains 10,000mg of North American wild milk thistle seeds and 500mg of concentrated silymarin extract per serving - Designed for individuals with liver damage from alcohol, fatty liver, or abnormal liver indicators, showing clinical evidence of improving liver function [2] - **Cardiovascular Shield: Natto Hard Capsules** - Contains 150mg of natto kinase per bottle, supporting cardiovascular health with a gentle and safe thrombolytic effect [2] - **Krill Oil Soft Capsules** - Contains 1,000mg of Antarctic krill oil, enhancing Omega-3 absorption and showing significant effects on blood lipid regulation [3] - **Fish Oil Soft Capsules** - Contains 400mg of DHA and 100mg of EPA, supporting brain and eye health, particularly beneficial for children's brain development and elderly cognitive maintenance [4] - **Joint and Respiratory Health: Quercetin Hard Capsules** - Demonstrates a 15% reduction in blood uric acid levels and a 35% decrease in gout attack risk [6] - **Anti-Aging and Immune Support: PQQ Collagen Hard Capsules** - Activates mitochondrial function and reduces oxidative damage to skin cells [7] - **Astaxanthin Soft Capsules** - Features a patented extraction method that improves absorption by 260%, significantly enhancing its antioxidant effects [8] - **Women's Multivitamin Tablets** - Provides a comprehensive nutrient profile to improve hair loss and enhance immunity [9] - **Brain Health and Sleep Management: Phosphatidylserine Hard Capsules** - Supports cognitive function and alleviates anxiety, particularly beneficial for students and high-pressure workers [14] Brand Positioning - Julydeer® aims to redefine dietary supplements with a focus on "precision nutrition," adhering to high standards of purity, concentration, absorption, and transformation [1] - The brand's claims are supported by scientific literature, avoiding absolute terms and disease treatment claims, thus ensuring compliance with advertising laws and health food regulations [1]