炒股就看金麒麟分析师研报，权威，专业，及时，全面，助您挖掘潜力主题机会！ 出品：新浪财经上市公司研究院 作者：喜乐 2025年上半年，港股IPO市场以"冰火两重天"的极端分化态势迎来近四年最强复苏：42家企业登陆港交所，合计募资1067亿港 元，较2024年上半年同比激增688%。这场由A to H大盘股与新经济赛道驱动的盛宴背后，中介机构的角色正经历深刻重构 ——头部保荐机构以百亿级承销规模主导市场格局，互联网券商借散户打新狂潮抢占份额，然而破发率高企、绿鞋机制失效、 承销"蹭单"成风等乱象，暴露出繁荣表象下中介责任的缺位。 （全文数据截至2025年6月30日） 中资机构凭借A to H项目资源优势占据市场主导地位 2025年上半年港股保荐市场呈现中资机构主导格局。前5名中，共有3家中资中介机构，其中中金公司以13单保荐、214.6亿港 元规模位居榜首，保荐规模较第二名华泰证券（9单、133.9亿港元）领先近2倍。中资券商在保荐市场的崛起，一方面得益于 港股IPO中A to H项目占据半壁江山，中资券商对A股公司的资源积累更具优势；另一方面也与近年外资机构活跃度降低，外 资中介对海外投资者的覆盖优势削弱等因 ...

一、活动时间 报名时间：即日起-2025年7月20日。 比赛时间：2025年7月16日-9月30日。 二、活动内容 4、ESG投资加分（5分）：鼓励选手在投资组合中持有ESG股票（ESG评级为A及以上），ESG投资情 况将作为决赛加分项（评分标准包括持仓期限、持仓比例、选股策略等）。 ESG股票参考产品列表下载查看： 方式一：关注微信公众号"东方财富金融素养"，回复"ESG股票"，获取产品列表。 方式二：网盘下载链接: https://pan.baidu.com/s/1wHUXjd224N9toZ7oxQRTqQ?pwd=43jb（提取码: 43jb） 5、仓位规定：大赛启动10个交易日内仓位达到60%-95%，且交易期间仓位需保持60%-95%。如在10个 交易日后低于或超出仓位上限，须在5个交易日内做出调整；停牌等特殊情况除外，允许在恢复正常交 易后3个交易日内再做出调整。 本赛事面向全国高校全日制本硕博学生，选手以个人形式报名参赛。大赛分为初赛和决赛：初赛阶段， 选手使用大赛模拟交易系统进行组合投资，初赛按照模拟投资综合收益率排名，最终排名前10名的选手 进入决赛。决赛为线下评比，根据选手初赛的投资业绩 ...

Core Insights - The article discusses the author's academic and professional background in Machine Learning, Economics, and Finance, highlighting expertise in Data Science and Machine Learning applications within the banking and finance sectors [1]. Group 1: Academic Background - The author holds a PhD in Machine Learning with a focus on Economics and Finance [1]. - The author has academic affiliations with IESE Business School, ESADE Business School, and the Barcelona Supercomputing Center [1]. Group 2: Professional Experience - The author has worked at Deloitte Financial Advisory, specializing in Data Science and Machine Learning applications for clients in banking, insurance, and finance [1]. - The author currently teaches Asset Pricing and Introduction to Corporate Finance at ESADE Business School at the MSc/BSc level [1]. Group 3: Research Focus - The current research of the author focuses on Generative AI in sustainable finance [1]. - The author's interests include machine learning and generative AI applications in finance and economics [1]. Group 4: Technical Proficiency - The author is proficient in programming languages such as Python, R, and SQL [1].

证券代码：300296 证券简称：利亚德 利亚德光电股份有限公司投资者关系活动记录表 编号：2025-11 | | ■特定对象调研 □分析师会议 | | --- | --- | | 投资者关 | □媒体采访 □业绩说明会 | | 系活动类 | □新闻发布会 □路演活动 | | 别 | ■现场参观 | | | □其他（电话会议） | | 参与单位 | 偕沣资产 王荣风 | | 名称及人 | 财达证券 李海潮 | | 员姓名 | | | 时间 | 2025 年 7 月 4 日 14:30-16:30 | | 地点 | 会议室 | | 上市公司 | 刘阳 董事会秘书兼副总经理 | | 接待人员 | 梁清筠 证券事务代表 | | 姓名 | | | | 本次调研以现场参观和会议交流的方式举行，会议中，董秘刘阳总对 | | | 公司整体业务进行了介绍并回答了投资者的提问，主要内容如下： | | | 一、公司整体业务情况 | | 投资者关 | 公司主营业务有三大板块，其中营收占比85%以上的是LED智能显示板块， | | 系活动主 | 另外两块是通过外延并购扩展的业务，一个是文旅夜游，这个业务曾经一度占 | | 要内容介 ...

Financial Performance & Growth - Total revenue for Q1 2025 reached $125 million, representing a 15% growth [6] - Galafold revenue in Q1 2025 was $1042 million, with a 14% patient demand growth [23] - Pombiliti + Opfolda revenue in Q1 2025 was $21 million, showing a 92% growth at CER [50] - The company expects to surpass $1 billion in total revenue in FY 2028 [6] Strategic Priorities & Guidance - The company aims for a total revenue growth of 15-22% at CER in FY 2025 [7, 77] - Galafold revenue is projected to grow by 10-15% at CER in FY 2025 [6, 7] - Pombiliti + Opfolda revenue is expected to increase by 50-65% at CER in FY 2025 [6, 7, 53, 77] - The company anticipates positive GAAP net income during H2 2025 [7, 77] Product & Market Overview - The global Fabry market is projected to reach approximately $3 billion by 2029 [14, 15] - The global Pompe market was approximately $15 billion in 2024 and is expected to exceed $2 billion by 2029 [42, 43] - DMX-200, a Phase 3 program for FSGS, addresses a market affecting over 40000 people in the US [67]

Clinical Programs & Data - CT-0508 monotherapy showed stable disease (SD) in 29% (4/14) of patients, with 44% SD in HER2 3+ patients [13] - 75% (6/8) of HER2 3+ patients exhibited a decrease in ctDNA, with reductions up to 93% [17] - CT-0525, a CAR-Monocyte therapy, has a ~2,000-fold increased exposure compared to CT-0508 in preclinical models [44] - The first patient was treated with CT-0525 in 2Q 2024, with initial data expected in 4Q 2024 [43] In Vivo CAR-M Collaboration with Moderna - The collaboration includes up to 12 targets, with 7 nominated [64] - Carisma received an $80 million upfront payment and is eligible for over $3 billion in potential milestones and royalties [64] - Nomination of the first development candidate targeting GPC3 for HCC triggered a $2 million milestone payment [6, 65] Financial Status - As of June 30, 2024, Carisma had $40.4 million in cash and cash equivalents [100] - The company's cash runway is expected to last into 3Q 2025 [6, 100] Fibrosis Program - Preclinical data demonstrates that engineered macrophages can reduce liver fibrosis, with Relaxin-IL10 macrophages showing >100% reduction in collagen in one model [84] - Nomination of a development candidate for liver fibrosis is expected in 1Q 2025 [8, 93]

212越野车旗下升级款 T01检阅官焕新亮相 近日，212越野车品牌旗下升级款T01检阅官的全新亮相。升级款 T01检阅官整合五大升级：视觉焕新、内饰升 级、舒适越级、越野强化、专属仪式感，令产品价值感实现全方位跃升。212越野车总经理陆云然表示："212越野 车一直在路上，与心怀年轻的人同频共振。年轻不仅是年龄的数字，更是热爱与探索。作为一个具有探索精神的 品牌，212越野车正在持续拓展自己的边界。" 升级款T01检阅官推出四款全新车色：龙血红、鸣沙黄、月岩灰、星辉银。新增方向盘加热和座椅通风功能，搭 配人体工学座椅和座椅按摩功能，其中方向盘加热功能，可在零下20℃低温环境，实现20秒内迅速升温。开启座 椅通风后，在35℃高温下，体感温度可快速降低3-5℃。新车采用前后50:50动力分配，共同实现更好、更稳定、 更硬核的脱困能力。搭配三种模式的分时四驱，从容应对不同路况。配备的防空灯在小于60km/h的低速越野时， 支持向左180°调节、向右30°探照，照亮前行路。 作为MG ALL in新能源的首款车型，全新MG4将率先实现OPPO在⻋机互联的全部能⻋，手机语音备车、手车应用 融合、手车无感互联、手机摇一 ...

7月4日盘后数据显示，兴业股份因价格波动登上龙虎榜。从买卖双方营业部构成来看，东方财富证券旗 下拉萨多个营业部及国信证券浙江互联网分公司成为当日交易焦点。 买入金额前五席位中，国信证券浙江互联网分公司以1268.81万元居首，该营业部近三个月上榜次数达 259次，其参与个股上榜后3日内上涨概率约35.14%。东方财富证券拉萨东环路第二营业部、团结路第 一营业部及金融城南环路营业部分别以1236.79万元、1155.39万元和1003.83万元紧随其后，三者在近三 个月的活跃度均超过700次上榜记录。此外，中国银河证券北京中关村大街营业部以886.78万元位列买 方第五。 卖出席位方面，东方财富证券拉萨团结路第一营业部以1009.13万元成为抛售主力，其近三个月上榜次 数高达907次。拉萨金融城南环路营业部、东环路第二营业部及东环路第一营业部分别卖出967.25万 元、957.10万元和881.71万元，国信证券浙江互联网分公司则以859.72万元位列卖方第五。值得注意的 是，拉萨系营业部在买卖双方榜单中均高频出现，显示其交易风格偏向短线博弈。 公开信息显示，兴业股份近一个月内累计上榜10次，近三个月上榜频率与 ...

Financial Status - Enanta Pharmaceuticals reported a strong balance sheet with $193.4 million in cash as of March 31, 2025[6] - The company is leveraging ongoing royalties to support its robust pipeline[6] Respiratory Syncytial Virus (RSV) - Zelicapavir (EDP-938) - Zelicapavir is the only N-inhibitor in clinical development for RSV[17] - A Phase 2 pediatric study showed a viral load decline of 1.18 log at Day 5 in a prespecified subset of patients[25] - A Phase 2 pediatric study showed a viral load decline of 1.4 log at the end of treatment in Part 2[30] - EDP-323, an RSV L-protein inhibitor, demonstrated an 85-87% reduction in viral load AUC in a human challenge model[42] Immunology - KIT Inhibitor (EPS-1421) - EPS-1421 inhibits KIT with nanomolar potency in both binding and cellular assays[63] - EPS-1421 exhibits greater than 500-fold selectivity for KIT over other KIT family members[68] - In mice, EPS-1421 inhibits SCF-mediated histamine release with an EC50 (free drug) of 0.25nM[65] Immunology - STAT6 Inhibitor - Prototype STAT6 inhibitors exhibit nanomolar inhibition in biochemical and cellular assays[84] - Prototype STAT6 inhibitor demonstrates good selectivity, with greater than 1000x biochemical selectivity for STAT6 over other STATs[88] - Prototype STAT6 oral inhibitor results in complete inhibition of pSTAT6 in a mouse model[93]

创业板指今日下跌0.36%，报收2156.23点，创业板全日成交额4204.54亿元，比上个交易日增加384.48亿 元。今日可交易创业板股中，237只股收盘上涨，涨幅超过10%的有10只，其中，广生堂、杭州园林、 隆扬电子等5股涨停，涨幅在5%至10%之间的有21只，收盘下跌的有1134只，跌幅超10%的有1只。 证券时报·数据宝统计显示，换手率方面，创业板今日平均换手率为4.42%，换手率区间分布显示，换手 率超过20%的有57只，换手率10%~20%之间的有144只，换手率5%~10%的有267只，换手率1%~5%的有 848只，换手率不足1%的有66只。 换手率最高的是逸豪新材，该股今日收盘上涨5.94%，全天换手率59.80%，成交额11.74亿元；其次是满 坤科技，该股今日收盘上涨2.88%，全天换手率46.59%，成交额7.76亿元；换手率居前的还有西测测 试、智立方、隆扬电子等，换手率分别为45.38%、43.96%、43.73%。 | 300030 | 阳普医疗 | 7.99 | 2.44 | 22.30 | -266.26 | | --- | --- | --- | --- | --- | ...