The Transplant Solutions Company •J u n e 5 , 2 0 2 5 Click to edit Master text styles Click to edit Master title style Patrick G, Kidney Transplant Recipient Safe Harbor Statement These slides and the accompanying oral presentation contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. All statements other than statements of historical fact contained in this presentation, including s ...

撰文丨王聪 编辑丨王多鱼 排版丨水成文 由于遗传密码系统的 简并性 （不止一个密码子对应同一个氨基酸） ，并非所有的单碱基突变都会导致氨基酸序列的改变。这类突变被称为 同义突变 ，在进化理 论中传统上被视为中性的。 2022 年，密歇根大学 张建之 教授团队在 Nature 期刊发表论文，指出酿酒酵母的同义突变可能大多是非中性的，同义突变和非同义突同样会破坏细胞适应性 【1】 。但这些发现仍存争议，重新激起了研究人员对于同义突变的生物学效应的兴趣和讨论。此外，一些早期研究显示， 病毒和原核生物中的同义突变可能会影 响它们的适应性。 然而，在非真核生物和酵母中得出的这些发现是否适用于哺乳动物，尤其是人类，目前仍不清楚。 2025 年 6 月 24 日，北京大学 魏文胜 教授、 刘莹 副研究员作为共同通讯作者，在 Nature Biotechnology 期刊发表了题为： Prime editor-based high- throughput screening reveals functional synonymous mutations in human cells 的研究论文 【2】 。 该研究开发了一种名 ...

Faruqi & Faruqi, LLP Securities Litigation Partner James (Josh) Wilson Encourages Investors Who Suffered Losses Exceeding $50,000 In Fortrea To Contact Him Directly To Discuss Their Options If you suffered losses exceeding $50,000 in Fortrea between July 3, 2023 and February 28, 2025 and would like to discuss your legal rights, call Faruqi & Faruqi partner Josh Wilson directly at 877-247-4292 or 212-983-9330 (Ext. 1310). [You may also click here for additional information] NEW YORK, June 24, 2025 (GLOBE NE ...

Ipsos completes the acquisition of The BVA Family Paris, 24 June 2025 - Ipsos, one of the world's leading market research companies, has completed the acquisition of The BVA Family. The operation was concluded after fulfilling all necessary regulatory requirements, including in-depth consultation with employee representatives in France and obtaining relevant competition authority approvals. This acquisition is a significant expansion for Ipsos in France and adds new strength in the UK and Italy. BVA notably ...

此次合作支持亚硝胺杂质检测，让申办方展示利福平在药物相互作用研究中的合理使用北卡罗来纳州达勒姆, June 24, 2025 (GLOBE NEWSWIRE) -- Fortrea（纳斯达克代码：FTRE，以下简称“公司”）是一家全球领先的合同研究组织（CRO），今日宣布与分析及生物分析领域领先的合同研究组织 Emery Pharma 建立战略合作。Emery Pharma 提供符合现行良好生产规范（cGMP）和良好实验室规范（GLP）的检测服务。该合作将为药物相互作用（DDI）研究中的首选药物利福平快速按批次进行1-甲基-4-亚硝基哌嗪（MNP）杂质检测，确保杂质含量低于美国食品药品监督管理局（FDA）指南设定的可接受摄入量（AI）限值。 Fortrea 选择 Emery Pharma，正是基于其在分析及生物分析检测方面的强大能力，以支持 Fortrea 全球临床项目的开展。 Emery Pharma 在该领域的专业优势，助力 Fortrea 在 DDI 研究中将利福平用作诱导 CYP3A4 同工酶的药剂。 此次宣布的合作使申办方能够使用利福平开展 DDI 评估——因其安全性及耐受性表现优异，常被推荐作为此 ...

Gartner Free Cash Flow May 6, 2025 © 2025 Gartner, Inc. and/or its affiliates. All rights reserved. Gartner is a registered trademark of Gartner, Inc. or its affiliates. This presentation, including all supporting materials, is proprietary to Gartner, Inc. and/or its affiliates and is for the sole internal use of the intended recipients. Because this presentation may contain information that is confidential, proprietary or otherwise legally protected, it may not be further copied, distributed or publicly di ...

NEW YORK, June 24, 2025 (GLOBE NEWSWIRE) -- Leading securities law firm Bleichmar Fonti & Auld LLP announces that a lawsuit has been filed against Fortrea Holdings Inc. (NASDAQ: FTRE) and certain of the Company’s senior executives for potential violations of the federal securities laws. If you invested in Fortrea you are encouraged to obtain additional information by visiting https://www.bfalaw.com/cases-investigations/fortrea-holdings-inc-class-action-lawsuit. Investors have until August 1, 2025, to ask th ...

Collaboration enables testing of nitrosamine impurities, allowing sponsors to demonstrate acceptable use of rifampin in drug-drug interaction studies DURHAM, N.C., June 24, 2025 (GLOBE NEWSWIRE) -- Fortrea (Nasdaq: FTRE) (the "Company"), a leading global contract research organization (CRO), today announced a strategic collaboration with Emery Pharma, a leading analytical and bioanalytical CRO providing testing services under current Good Manufacturing Practice (cGMP) and Good Laboratory Practice (GLP), to ...

NEW YORK, June 23, 2025 (GLOBE NEWSWIRE) -- The Gross Law Firm issues the following notice to shareholders of Fortrea Holdings Inc. (NASDAQ: FTRE). Shareholders who purchased shares of FTRE during the class period listed are encouraged to contact the firm regarding possible lead plaintiff appointment. Appointment as lead plaintiff is not required to partake in any recovery. CONTACT US HERE: https://securitiesclasslaw.com/securities/fortrea-holdings-inc-loss-submission-form/?id=153678&from=3 CLASS PERIOD: Ju ...

Here are three stocks added to the Zacks Rank #5 (Strong Sell) List today:Ares Capital (ARCC) is a specialty finance company, which primarily invests in U.S. middle-market companies. The Zacks Consensus Estimate for its current year earnings has been revised 7.8% downward over the last 60 days.Baidu (BIDU)  is a Chinese-language Internet search provider. The Zacks Consensus Estimate for its current year earnings has been revised 6.5% downward over the last 60 days.Bruker (BRKR) designs and manufactures prop ...