Core Insights - 22nd Century Group is advancing a 100mm VLN® reduced nicotine content cigarette, targeting an FDA submission by Q4 2025, expanding its product line aimed at nicotine harm reduction [1][4] - The new 100mm product is designed to appeal to approximately half of the U.S. smoking population who prefer this size, enhancing the reach of VLN® products [3][4] - The company emphasizes that its proprietary reduced nicotine content tobacco has been validated through independent clinical studies, demonstrating effectiveness in reducing smoking behaviors [3][6] Product Development - The 100mm VLN® cigarette will be available under both VLN® branding and partner brands like Smoker Friendly and Pinnacle, if authorized [2] - The VLN® cigarette contains 95% less nicotine than traditional cigarettes, which has been shown to help smokers reduce consumption and increase quit attempts [6][9] Market Position - 22nd Century Group is positioned as a pioneering company in nicotine harm reduction within the tobacco industry, focusing on providing smokers with choices to control their nicotine consumption [5][7] - The company operates a manufacturing facility in Mocksville, North Carolina, capable of producing over 45 million cartons of combustible tobacco products annually, with room for expansion [8]