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4th Generation Lentiviral Vector (LV) TetraVecta™ System
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OXB to Present at the 28th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT)
Globenewswire· 2025-05-09 11:00
Core Viewpoint - OXB will participate in the 28th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT) from May 13 to May 17, 2025, showcasing its expertise in viral vector development and manufacturing [1][2]. Group 1: Event Participation - OXB will exhibit at Booth 1611, allowing delegates to meet its team of viral vector experts and explore its capabilities in lentiviral, AAV, and other viral vector types [2]. - The company will contribute to the scientific program with an industry-sponsored symposium, five poster presentations, and two oral presentations [2]. Group 2: Presentations and Topics - The industry-sponsored symposium is titled "Accelerate Time to Clinic: A Process and Analytics Platform Approach" [3]. - Poster presentations will cover various topics, including: - "The 3 Rs of Replication-Competent Lentivirus (RCL) Formation Risk: Real, Rare, or Artificial?" - "Enhancing Titers of Therapeutic Lentiviral Vectors using PKC Agonists" - "Optimising the Production of the 4th Generation Lentiviral Vector (LV) TetraVecta™ System: Towards Plug-and-Play LV Manufacturing" - "The Impact of Individual Helper Genes on AAV Productivity" [4]. Group 3: Oral Presentations - Oral presentations will include: - "Enhancing Upstream Processes for High-Yield, High-Quality AAV Vector Production Using a Novel In-House Cell Line" - "Diving Deeper: Using a SYBR Gold Capsid Ejection Assay as an Orthogonal Method of Measuring Potency and VP1 Deamidation in AAV9 Drug Product Samples" [6]. Group 4: Company Background - OXB is a global quality and innovation-led contract development and manufacturing organization (CDMO) specializing in cell and gene therapy, with 30 years of experience in viral vectors [9][10]. - The company collaborates with leading pharmaceutical and biotechnology firms, providing expertise in various viral vector types, including lentivirus and AAV [9]. - OXB's capabilities range from early-stage development to commercialization, supported by robust quality-assurance systems and regulatory expertise [9].