For more information visit the Company's website at www.freseniusmedicalcare.com. Disclaimer:This release contains forward-looking statements that are subject to various risks and uncertainties. Actual results could differ materially from those described in these forward-looking statements due to various factors, including, but not limited to, changes in business, economic and competitive conditions, legal changes, regulatory approvals, results of clinical studies, foreign exchange rate fluctuations, uncer ...

Core Insights - Fresenius Medical Care (FMS) has launched the "FME Reignite" strategy aimed at achieving industry-leading profitability while optimizing capital structure and advancing innovation in renal care [1][7] - The strategy includes a significant expansion of the FME25 program, now called FME25+, targeting €1.05 billion in sustainable cost savings by 2027, which is a €300 million increase from previous goals [2] - The establishment of Value-Based Care (VBC) as a standalone segment is expected to enhance transparency and contribute to growth, having generated €1.8 billion in revenues in 2024 [3] Profitability and Operational Focus - The FME25+ program focuses on operational excellence and margin expansion, aiming for mid-teens operating income margin by 2030 across Care Delivery and Care Enablement segments [2] - The program enhances scalability, standardization, and efficiency across clinics and manufacturing sites, leveraging synergies to streamline service delivery while maintaining care quality [4] Capital Structure and Shareholder Value - A new capital allocation framework aims to balance reinvestment and shareholder returns, with plans to allocate €800 million to €1 billion annually for capital expenditures through 2030 [5][8] - Fresenius will initiate a €1 billion share buyback program over two years starting in 2025 and has committed to a dividend payout ratio of 30-40% [8] Technological Advancements - The upcoming U.S. launch of the 5008X CAREsystem, a next-generation dialysis machine, is a cornerstone of the strategy, expected to improve clinical outcomes and operational efficiencies [10][11] - The 5008X system has shown a 4.4% mortality reduction over 2.5 years compared to conventional hemodialysis, promising lower hospitalization rates and improved treatment consistency [10] Competitive Positioning - Through the FME Reignite strategy, Fresenius is positioning itself as a financially disciplined, innovation-driven, and patient-centered leader in renal care, combining cost control with growth investments [12] - Compared to competitors like Baxter International, DaVita Inc., and Outset Medical, Fresenius has outperformed in share price, with a 19.8% increase year-to-date against the industry's decline of 12% [17]

Core Viewpoint - Fresenius Medical Care is advancing its high-volume hemodiafiltration (HVHDF) kidney replacement therapy in the U.S. following FDA clearance for its updated 5008X CAREsystem, marking a significant step in the company's commercialization strategy for 2025 and a full-scale launch in 2026 [1][2][7] Company Developments - The updated 5008X CAREsystem received FDA 510(k) clearance, enabling Fresenius Medical Care to enhance patient care through improved dialysis technology [2][4] - The company plans to deploy the new system in a first wave of Fresenius Kidney Care clinics throughout 2025, with broader implementation expected in 2026 [2][3] - The 5008X CAREsystem features the Fresenius Clinical Data Exchange® (CDX), which allows for direct access to medical information systems at the chairside, optimizing clinic workflows and reducing clutter [2][4] Industry Context - Hemodiafiltration is already the standard treatment in many regions, including Europe, Latin America, and Asia, and the company aims to establish this standard in the U.S. [2] - The CONVINCE study demonstrated a 23% reduction in mortality rates for patients using high-volume hemodiafiltration compared to traditional high-flux hemodialysis, highlighting the potential benefits of this therapy [5][8] Market Potential - There are approximately 160,000 in-center hemodialysis machines in the U.S. that could be replaced with the new standard of care, indicating a significant market opportunity for Fresenius Medical Care [3]