Core Insights - MaxCyte, Inc. reported total revenue of $7.3 million for Q4 2025, which is at the top of the previously announced range, and full-year revenue of $33.0 million, also at the top of the range [1][13] - The company expects 2026 revenue to be between $30 million and $32 million, with core revenue projected at $25 million to $27 million and SPL Program-related revenue at approximately $5 million [1][20] Financial Performance - Q4 2025 total revenue decreased by 16% compared to Q4 2024, while core business revenue fell by 22% in the same period [7][9] - For the full year 2025, total revenue decreased by 15% compared to 2024, with core business revenue down by 9% [13][14] - Gross profit for Q4 2025 was $5.7 million, representing a gross margin of 78%, compared to a gross margin of 74% in Q4 2024 [10] - The company reported a net loss of $9.6 million for Q4 2025, an improvement from a net loss of $10.6 million in Q4 2024 [12] Strategic Developments - In 2025, MaxCyte signed 4 new SPL agreements and aims to expand its sales pipeline across its ExPERT electroporation platform and SeQure assay services [3] - The company anticipates supporting up to four therapies in Phase III by the end of 2026, having already received a milestone payment for one of these therapies [3] Cash Position - As of December 31, 2025, total cash, cash equivalents, and investments were $155.6 million, with expectations to end 2026 with at least $136 million [1][16]

Core Viewpoint - MaxCyte, Inc. is set to release its financial results for Q4 and full year 2025 on March 24, 2026, after U.S. market close, with a conference call scheduled for 4:30 p.m. Eastern Time to discuss these results [1]. Group 1: Financial Results Announcement - The financial results for the fourth quarter and full year 2025 will be announced after the U.S. market closes on March 24, 2026 [1]. - A conference call will be held at 4:30 p.m. Eastern Time to discuss the financial results [1]. Group 2: Conference Call Details - Investors interested in the conference call must register online, with a recommendation to register at least a day in advance [2]. - A live and archived webcast of the conference call will be available on the MaxCyte website [2]. Group 3: Company Overview - MaxCyte is a leading cell-engineering company focused on advancing the discovery, development, and commercialization of next-generation cell therapies [3]. - The company utilizes Flow Electroporation technology and SeQure DX gene editing risk assessment services to enable precise and scalable cell engineering [3]. - With over 25 years of experience, MaxCyte aims to shape the future of medicine by empowering researchers globally to develop safe and effective treatments [3].

Core Viewpoint - MaxCyte, Inc. is set to release its financial results for Q3 2025 on November 5, 2025, after the U.S. market closes, followed by a conference call to discuss these results [1]. Company Overview - MaxCyte is a leading cell-engineering company focused on advancing the discovery, development, and commercialization of next-generation cell therapies [3]. - The company utilizes its Flow Electroporation technology and SeQure DX™ gene editing risk assessment services to enable precise and scalable cell engineering [3]. - With over 25 years of experience, MaxCyte aims to empower researchers globally to engineer diverse cell types and payloads, thereby accelerating the development of safe and effective treatments [3]. Investor Relations - Investors interested in the upcoming conference call must register online, with a recommendation to do so at least a day in advance [2]. - A live and archived webcast of the conference call will be available on the MaxCyte website [2].

Core Insights - MaxCyte has signed a Strategic Platform License agreement with Moonlight Bio to utilize its Flow Electroporation technology and ExPERT™ platform for T cell therapy development [1][2][3] - The partnership aims to enhance the scalability and efficiency of Moonlight Bio's gene-edited T cell therapies, particularly targeting solid tumors [2][3][5] Company Overview - MaxCyte is a leading cell-engineering company focused on advancing cell-based therapeutics through its Flow Electroporation technology and SeQure™ gene editing services [4] - The company has over 25 years of experience in cell engineering and aims to empower researchers globally to develop safe and effective treatments [4] Moonlight Bio's Objectives - Moonlight Bio is a preclinical-stage biotechnology company dedicated to developing enhanced T cell therapies for cancer patients, particularly for solid tumors [5] - The company seeks to overcome the limitations of current therapies that fail to provide durable responses in solid tumor treatments [5]

Core Insights - MaxCyte, Inc. reported a total revenue of $8.5 million for Q2 2025, a decrease of 18% compared to $10.4 million in Q2 2024, primarily due to changes in the operating environment and customer inventory management [7][5][3] - Core business revenue increased by 8% to $8.2 million in Q2 2025 from $7.6 million in Q2 2024, driven by sales of instruments and consumables [5][7] - The company has lowered its 2025 guidance, expecting core revenue to be flat to a 10% decline compared to 2024, and SPL Program-related revenue to be approximately $5 million for the year [11][14] Financial Performance - Gross profit for Q2 2025 was $7.0 million, representing an 82% gross margin, down from $8.9 million and 86% gross margin in Q2 2024 [8][7] - Operating expenses increased to $21.2 million in Q2 2025 from $20.9 million in Q2 2024, contributing to a net loss of $12.4 million compared to a net loss of $9.4 million in the same period last year [10][9] - The installed base of instruments grew to 814 units in Q2 2025, up from 723 units in Q2 2024 [6] Strategic Developments - MaxCyte added two new Strategic Platform License (SPL) clients, Adicet Bio and Anocca AB, bringing the total number of SPL agreements to 31 [5][3] - The company remains focused on enhancing operational efficiencies and investing in product improvements, including SeQure Dx, to support its position in the cell and gene therapy industry [3][5] Cash Position - As of June 30, 2025, total cash, cash equivalents, and investments were $165.2 million, reflecting a decrease due to acquisition-related costs [5][11] - The company expects to end 2025 with at least $155 million in total cash, cash equivalents, and investments [11]

Core Viewpoint - MaxCyte, Inc. is set to release its financial results for Q2 2025 on August 6, 2025, after the U.S. market closes, followed by a conference call to discuss these results [1]. Group 1: Financial Results Announcement - The financial results for the second quarter of 2025 will be announced after the U.S. market closes on August 6, 2025 [1]. - A conference call will be hosted by company management at 4:30 p.m. Eastern Time to discuss the financial results [1]. Group 2: Conference Call Details - Investors interested in the conference call must register online, with a recommendation to register at least a day in advance [2]. - A live and archived webcast of the event will be available on the "Events" section of the MaxCyte website [2]. Group 3: Company Overview - MaxCyte is a leading cell-engineering company focused on advancing the discovery, development, and commercialization of next-generation cell therapies [3]. - The company utilizes Flow Electroporation technology and SeQure DX™ gene editing risk assessment services to enable precise and scalable cell engineering [3]. - With over 25 years of experience, MaxCyte aims to shape the future of medicine by empowering researchers globally to develop safe and effective treatments [3].

Core Viewpoint - MaxCyte and Ori Biotech have formed a strategic collaboration to enhance the efficiency, scalability, and productivity of cell therapy manufacturing by integrating their respective platforms, ExPERT™ and IRO® [1][4]. Group 1: Collaboration Details - The collaboration combines MaxCyte's ExPERT™ platform, known for its efficient transfection capabilities, with Ori's IRO platform, which automates cell therapy manufacturing [2][3]. - The initial evaluation will focus on optimizing the yield and manufacturing timelines of MaxCyte-engineered primary T cells using CD19 CAR expression via CRISPR knock-in [2][3]. Group 2: Technological Integration - MaxCyte's technology provides flexibility and efficiency in transfecting cells at a clinical scale, integrating well with various processes in cell therapy workflows [3]. - Ori's IRO platform enhances cell culture efficiency through automated fluid handling and customizable mixing, contributing to improved scalability [3]. Group 3: Leadership Insights - MaxCyte's CEO expressed excitement about the collaboration, emphasizing the commitment to improving manufacturing processes and accelerating the availability of cell therapies [4]. - Ori's CEO highlighted the partnership as a demonstration of their dedication to providing scalable solutions that address challenges in cell and gene therapy manufacturing [4]. Group 4: Industry Impact - The collaboration aims to enable therapy developers to adopt integrated solutions, thereby accelerating the transition from research to commercialization and increasing patient access to next-generation treatments [4].