Core Insights - Myriad Genetics announced that treatment informed by the GeneSight test resulted in faster initial remission and response in patients with Major Depressive Disorder (MDD), with benefits persisting over six months [1][2][3] Group 1: Study Overview - The PRIME Care study is the largest pharmacogenomic randomized controlled trial in mental health, enrolling 1,944 U.S. Veterans with depression to assess the impact of GeneSight results on treatment outcomes [2][4] - The study found that patients whose clinicians had GeneSight results were significantly more likely to achieve remission over 24 weeks, with a 28% higher likelihood compared to the usual care group [5][6] Group 2: Post-Hoc Analysis Findings - The post-hoc analysis included 1,764 veterans and focused on the time to first remission and response, showing that GeneSight test results increased the rate of remission and response over time [3][6] - Patients who took the GeneSight test were 27% more likely to achieve remission and 21% more likely to experience a significant reduction in depressive symptoms [8] Group 3: GeneSight Test Information - The GeneSight Psychotropic test is a leading pharmacogenomic test for over 60 medications commonly prescribed for mental health conditions, aimed at reducing the trial-and-error process in medication prescribing [7][8] Group 4: Company Background - Myriad Genetics is a leader in molecular diagnostic testing and precision medicine, dedicated to advancing health and well-being through molecular tests that guide treatment decisions across various medical specialties [8][9]

Core Insights - Myriad Genetics, Inc. (MYGN) has demonstrated the superiority of its GeneSight Psychotropic test over treatment-as-usual (TAU) for patients with major depressive disorder (MDD) who have experienced treatment failure, as evidenced by a recent meta-analysis published in the Journal of Clinical Psychopharmacology [1][9] Company Summary - The GeneSight Psychotropic test analyzes 64 medications commonly prescribed for depression, anxiety, ADHD, and other psychiatric conditions, helping clinicians understand how a patient's genetics may affect their response to these medications [6] - The recent meta-analysis included six prospective, controlled trials with a total of 3,532 unique adults with MDD, showing that patients using the GeneSight test were 41% more likely to achieve remission and 30% more likely to respond compared to those receiving TAU [7][8][9] - Myriad Genetics has a market capitalization of $631.8 million and a long-term EPS growth rate of 33.1%, significantly higher than the industry average of 21.1% [5] Industry Summary - The mental health tester market is projected to reach $5.10 billion by 2033, growing at a compound annual growth rate of 8.6% from 2026 to 2033, driven by increasing awareness of mental health issues and demand for effective assessment methods [10]

Core Insights - Myriad Genetics announced a meta-analysis showing that the GeneSight Psychotropic test significantly improves response and remission rates in patients with major depressive disorder (MDD) compared to treatment as usual (TAU) [1][2][3] Study Details - The meta-analysis included six prospective controlled studies with a total of 3,532 adults with MDD who had experienced at least one treatment failure [4] - Response was defined as a 50% or greater improvement in depression scores, while remission was defined as a score of seven or less on the Hamilton Depression Rating Scale (HAM-D17) or five or less on the Patient Health Questionnaire (PHQ-9) [4] GeneSight Test Overview - The GeneSight Psychotropic test analyzes how a patient's genes may affect their response to 64 commonly prescribed psychiatric medications, aiming to reduce the trial-and-error process in medication management [5] Company Background - Myriad Genetics is a leader in molecular diagnostic testing and precision medicine, focusing on improving patient care and reducing healthcare costs through molecular insights [6]

Core Insights - A significant majority of Americans diagnosed with depression and/or anxiety believe mental health medications are effective, yet concerns about side effects prevent over half from taking them [1][2] - Genetic testing for mental health medications is viewed positively, with 54% of patients believing it could alleviate concerns regarding side effects [2][3] Company Overview - Myriad Genetics, Inc. is a leader in molecular diagnostic testing and precision medicine, offering the GeneSight test which analyzes how a patient's genes may influence their response to mental health medications [1][11] - The GeneSight test is recognized as a category-leading pharmacogenomic test for over 60 medications commonly prescribed for psychiatric conditions [11][12] Survey Findings - The GeneSight Mental Health Monitor survey indicates that 62% of patients whose providers did not use PGx testing wished they had been informed about it [3] - The survey also revealed that 67% of Americans believe it is socially acceptable to take medications for mental health, and 66% have a positive view of others taking such medications [8][9] Patient Experience - The case of a patient, Lisa Roberts, illustrates the practical benefits of the GeneSight test in prescribing effective medication without the lengthy trial-and-error process [5][6] - The survey results show that respondents rated the effectiveness of mental health medications similarly to medications for other chronic conditions, such as high blood pressure and high cholesterol [6]