Core Insights - Heartflow, Inc. reported a strong financial performance for Q4 2025, achieving a 40% year-over-year revenue growth, concluding a record year for the company [3][4][13] - The company anticipates continued growth in 2026, projecting total revenue between $218 million and $222 million, representing approximately 24% to 26% growth year-over-year [11] Financial Performance - Total revenue for Q4 2025 was $49.1 million, a 40% increase from $34.98 million in Q4 2024 [4][28] - U.S. revenue reached $44.8 million, up 41% year-over-year, while international revenue was $4.3 million, a 35% increase [4] - Gross profit for Q4 2025 was $39.1 million, compared to $26.3 million in the prior year, with a gross margin of 79.5% [5][6] - Total operating expenses were $56.8 million, or 116% of total revenue, down from 121% in the prior year [7][16] - The net loss for Q4 2025 was $24.4 million, or ($0.29) per share, significantly improved from a net loss of $33 million, or ($5.59) per share, in Q4 2024 [9][10] Annual Overview - For the full year 2025, Heartflow reported total revenue of $176 million, a 40% increase from $125.8 million in 2024 [13][28] - The gross margin for the full year was 76.8%, up from 75.1% in the previous year [15] - The net loss for 2025 was $116.8 million, or ($3.17) per share, compared to a net loss of $96.4 million, or ($17.98) per share, in 2024 [17] Market Position and Growth Strategy - Heartflow's technology is being adopted by over 1,800 institutions globally, with a focus on expanding its commercial presence [20] - The company has made significant progress in scaling account activations and driving early physician adoption of Heartflow Plaque Analysis [3] - Aetna's coverage of Heartflow Plaque Analysis has increased the total U.S. covered lives for Plaque to approximately 75% [11] Future Outlook - Heartflow's 2026 guidance reflects strong business fundamentals and confidence in consistent execution, with commercial, innovation, and clinical catalysts anticipated [3] - The company expects non-GAAP gross margin to be between 80% and 81% for 2026 [11]

Investor Presentation January 2026 Disclaimers Forward-Looking Statements This presentation includes express or implied forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this presentation, including statements regarding our strategy, future financial condition, future operations, projected costs, prospects, plans, objectives of management ...