Hereditary Cancer

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Tempus AI's 89% Genomics Surge: Will the Momentum Keep Building?
ZACKS· 2025-06-20 13:46
Core Insights - Tempus AI reported $193.8 million in Genomics revenues for Q1 2025, marking an increase of nearly 89% year over year, driven by a 20% growth in oncology test volumes and higher average revenue per test due to increased Medicare reimbursement rates [1][8] - The company is set to launch a new liquid biopsy assay, xM for treatment response monitoring, which will track changes in tumor fraction during immune-checkpoint inhibitor therapies, potentially influencing treatment decisions [2] - Tempus is also preparing to launch its first whole-genome sequencing test, Xh, aimed at detecting clinically relevant variants in hematological oncology by next year [3] - A companion diagnostic test is being developed in collaboration with Verastem Oncology, leveraging Tempus' FDA-approved xT CDx assay in clinical trials for ovarian cancer treatment [4] Industry Updates - Guardant Health reported a 20% year-over-year growth in oncology revenues, with a 25% increase in test volumes, and launched a hereditary cancer test [5] - Exact Sciences is experiencing strong international adoption of its Oncotype DX genomic test and has launched Cologuard Plus, which is expected to reduce false positives significantly [6] Financial Performance - Tempus AI shares have increased by 105.3% year to date, outperforming the industry average growth of 28% [7] - The company is trading at a forward Price-to-Sales ratio of 8.60X, compared to the industry average of 6.02X [9] - The Zacks Consensus Estimate for Tempus AI's 2025 earnings has been trending upward over the past 90 days, indicating positive market sentiment [11]
Myriad Genetics Highlights New Research Advancements and Oncology Innovations at 2025 ASCO Annual Meeting
Globenewswire· 2025-05-27 20:05
Core Insights - Myriad Genetics will present data from seven new research studies at the 2025 ASCO Annual Meeting, focusing on Molecular Residual Disease (MRD) clinical outcomes from the MONSTAR-SCREEN-3 study [1][3] - The company emphasizes its commitment to advancing precision oncology through its comprehensive portfolio of genetic and tumor genomic testing solutions [1][3][7] MRD Studies - An oral abstract titled "Ultra-sensitive pan-cancer molecular residual disease assessment using whole-genome sequencing-based personalized ctDNA panel" will be presented, showcasing successful ctDNA detection across over 100 patients with a baseline detection rate of 100% [2] - The interim results indicate the ability to detect tumor fractions as low as 0.0001% and provide a lead time in detecting recurrence compared to imaging [2] Myriad Oncology Portfolio - Myriad Oncology will unveil a new brand identity at the ASCO meeting, highlighting its streamlined approach to germline testing, tumor profiling, and companion diagnostic testing [4] - Upcoming product innovations include the integration of Myriad's oncology portfolio with Flatiron's OncoEMR and Epic cloud-based platforms, enhancing workflow for clinicians [6] Product Innovations - The Precise MRD test, based on whole genome sequencing, is designed to monitor tumor-specific variants and is expected to launch commercially in 2026 [11] - The Prolaris Prostate Cancer Prognostic Test, utilizing AI technology, is anticipated to launch in early 2026, providing clinicians with data-driven insights for treatment decisions [11] - An expanded MyRisk Gene Panel is set to launch later this year, incorporating more clinically actionable genes based on national guidelines [11]
Myriad (MYGN) Q1 Earnings: Taking a Look at Key Metrics Versus Estimates
ZACKS· 2025-05-07 00:35
Core Insights - Myriad Genetics reported $195.9 million in revenue for the quarter ended March 2025, reflecting a year-over-year decline of 3.1% and an EPS of -$0.03 compared to -$0.01 a year ago [1] - The revenue fell short of the Zacks Consensus Estimate of $199.96 million by 2.03%, while the EPS exceeded the consensus estimate of -$0.05 by 40% [1] Revenue Performance by Product - Prenatal revenue reached $49.30 million, surpassing the estimated $44.69 million, marking a year-over-year increase of 59.6% [4] - Hereditary Cancer revenue was $86.30 million, below the average estimate of $92.46 million, representing a year-over-year decline of 2% [4] - Pharmacogenomics revenue totaled $31 million, slightly below the estimated $32.46 million, with a year-over-year decrease of 20.3% [4] - Tumor Profiling revenue was $29.30 million, compared to the average estimate of $30.66 million, indicating a year-over-year decline of 5.2% [4] Stock Performance - Myriad's shares have returned -4.6% over the past month, contrasting with the Zacks S&P 500 composite's increase of 11.5% [3] - The stock currently holds a Zacks Rank 2 (Buy), suggesting potential outperformance against the broader market in the near term [3]