Core Insights - Molecular Instruments and Standard BioTools have announced a strategic collaboration to enhance Imaging Mass Cytometry (IMC) workflows using HCR imaging technologies, specifically the HCR HiFi Encoder for protein imaging with any primary antibody [1][4][5] Group 1: Collaboration Details - The partnership aims to create a unified platform for high-fidelity multi-omic analysis of RNA and protein targets in complex tissues, enabling amplified detection through HCR Gold and direct protein encoding via the HCR HiFi Encoder [2][4] - This collaboration integrates HCR Gold for RNA and protein imaging with the Hyperion Imaging System, marking the first time amplified detection for both RNA and protein is introduced in IMC technology [3][4] Group 2: Technological Advancements - The integration of HCR amplification with the Hyperion platform is expected to increase sensitivity, enhance flexibility, and accelerate the path from discovery to clinical translation [5] - The collaboration allows researchers to utilize their own primary antibodies in a simplified workflow while achieving robust visualization of low-abundance markers, significantly improving the sensitivity and flexibility of IMC spatial biology workflows [3][4] Group 3: Future Developments - Joint development activities are currently underway, with early-access opportunities available for interested collaborators [6]