Core Insights - PacBio has joined the 1000 Genomes Long Read Sequencing Project to contribute long-read transcriptome data, enhancing the understanding of human genomics [1][2][3] - The collaboration aims to provide new transcript-level insights from approximately 1,000 samples, supporting accurate gene expression interpretation and regulatory element analysis [2][3] - The project emphasizes transparency and open data, with all sequencing data and analysis pipelines to be publicly available [4][5] Company Contributions - PacBio will utilize its Kinnex RNA kits and Revio sequencing platform to generate full-length isoform sequencing data, with each sample expected to yield around 10 million full-length transcript reads [3] - The collaboration involves key laboratories, including the University of Washington and Johns Hopkins University, to deliver a high-quality RNA resource and scalable bioinformatics pipelines [3][4] Industry Impact - The addition of isoform sequencing to the 1000 Genomes Project is expected to enrich the foundational genomic resource, aiding in diverse applications from basic biology to rare disease diagnostics [3] - The initiative aims to advance equity, access, and innovation in human genetics research, contributing to the fast-growing field of long-read transcriptomics [5]