Core Insights - The company achieved a third consecutive quarter of year-over-year revenue growth, driven by a strategic pivot towards the high-demand U.S. AI-driven discovery market [1] - The company signed its first one-year enterprise Lens AI platform contract, transitioning from one-off project fees to predictable, monthly recurring revenue [1] Technology and Innovation - The Lens AI platform is differentiated by focusing on the 'invariant functional layer' of biology (HIFT) rather than surface sequence similarity, enabling the detection of IP risks and functional adjacencies that competitors may overlook [1] - The HIFT approach was validated by identifying a single conserved functional feature across over 2,000 influenza sequences, representing a potential target for a universal immunogen [1] - The dengue program was advanced by targeting a single conserved epitope present in all four serotypes, aiming to address the historical 'antibody-dependent enhancement' failure mode of previous vaccines [1] - The B Cell LAMA platform was launched to address the 'chain-pairing problem' in multispecific antibody development by utilizing naturally matured llama nanobodies that lack light chains [1] Strategic Focus - The company divested its European operations to concentrate capital and resources on North American commercial growth and Canadian laboratory capabilities [1]

Financial Data and Key Metrics Changes - Fiscal year 2025 marked a record-setting year for the company, with fourth-quarter revenue reaching $7 million, the highest in the company's history, representing an 8.1% increase year-over-year and a 13.5% increase quarter-over-quarter [4][16] - Gross margin improved to 64% in the fourth quarter, up from 48% in the same quarter last year, and 55% for the full fiscal year, an increase from 49% in fiscal year 2024 [4][17] - Adjusted EBITDA loss narrowed to $316,000 in the fourth quarter, a significant improvement from a loss of $1.7 million in the same quarter last year [6][19] - Cash position improved to $10.8 million as of April 30, 2025, compared to $3.5 million at the end of fiscal year 2024 [20] Business Line Data and Key Metrics Changes - The BioStrand segment experienced exceptional growth, increasing over 180% year-over-year, with gross margins approaching 90% [5][17] - Canadian business showed strong growth, with sales orders reaching $4.3 million in the fourth quarter, more than double historical quarters, and year-over-year sales in Canada increased by 47% [6][17] Market Data and Key Metrics Changes - The company is actively divesting its Dutch subsidiary, with the process in the final stages, which is expected to streamline operations and generate additional cash [7][8] - The company plans to rebrand shortly after the divestiture to reinforce its position as a bio-native AI platform [9] Company Strategy and Development Direction - The company is shifting from a service-oriented model to a customizable platform-driven business, focusing on AI and data integration in drug discovery [9] - Strategic collaborations have been established, including partnerships with Ribopro and a publicly traded technology company, aimed at enhancing therapeutic development offerings [10][11] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in entering the new fiscal year with a financially disciplined position to support growth, driven by strong cash position and validated AI economics [20] - The company anticipates continued growth in its core capabilities and expects the trend of increased inquiries related to IND applications to persist [35] Other Important Information - The FDA's plans to phase out animal testing for monoclonal antibodies align with the company's Lens AI capabilities, which predict toxicity and immune response [11] - The company regained compliance with Nasdaq's minimum bid price requirement, reflecting growing market confidence [13] Q&A Session Summary Question: What should be expected for the clinical development of GLP-one peptides? - The company is working with two partners on drug product manufacturing and unique administration routes, with plans to bring in a financial sponsor for clinical trials [22][24] Question: What milestones are needed to recognize payments from the biotech partner on oncology assets? - Initial payments are expected to be visible in the second quarter, with no unusual deal-breaking milestones [25][27] Question: What traffic has been seen for services since the FDA's guidance on AI-based systems? - There has been a significant increase in inquiries related to IND applications, particularly for immunogenicity and epitope mapping [29][35] Question: How far along is the divestment of European facilities? - The divestment process is in the final stages, with a dedicated buyer and no expected detrimental impact on the Canadian facility [36][39]

Financial Data and Key Metrics Changes - Fiscal year 2025 marked a record-setting year for the company, with fourth-quarter revenue reaching $7 million, the highest in its history, representing an 8.1% increase year-over-year and a 13.5% increase quarter-over-quarter [5][18] - Gross margin for the fourth quarter was 64%, up from 48% in the same quarter last year, and gross margins for the full fiscal year increased from 49% to 55% [5][19] - Adjusted EBITDA loss narrowed to $316,000 in the fourth quarter, a significant improvement from a loss of $1.7 million in the same quarter last year [7][21] - Cash position improved to $10.8 million as of April 30, 2025, compared to $3.5 million at the end of fiscal year 2024 [22] Business Line Data and Key Metrics Changes - The BioStrand segment experienced exceptional growth, increasing over 180% year-over-year, with gross margins approaching 90% [6][19] - Canadian business showed strong growth, with sales orders reaching $4.3 million in the fourth quarter, more than double historical quarters, and year-over-year sales in Canada increased by 47% [7][19] Market Data and Key Metrics Changes - Orders from new clients rose 93% year-over-year and 80% quarter-over-quarter, indicating strong market demand [7] - The company is actively divesting its Dutch subsidiary, which is expected to enhance focus and streamline operations [8][9] Company Strategy and Development Direction - The company plans to rebrand to reinforce its position as a bio-native AI platform, shifting from a service-oriented model to a customizable platform-driven business [9][10] - Strategic collaborations have been established, including partnerships with Ribopro and a multibillion-dollar technology company, aimed at enhancing therapeutic development and antibody drug conjugates [11][12] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's financial position and operational efficiencies, anticipating continued growth driven by the BioStrand segment and the Lens AI platform [22][49] - The FDA's plans to phase out animal testing align with the company's capabilities, potentially increasing demand for its AI-driven services [12][33] Other Important Information - The company has made significant advancements in its dengue vaccine program and GLP-1 peptide, showcasing the versatility of its platform [13][14] - The company regained compliance with Nasdaq's minimum bid price requirement, reflecting growing market confidence [14] Q&A Session Summary Question: What should be expected for the clinical development of GLP-1 peptides? - The company is working with two partners on drug product manufacturing and unique administration routes, with plans to bring in a financial sponsor for clinical development [24][25] Question: What milestones are needed to recognize initial payments from the biotech partner? - Initial payments are expected to be visible in the second quarter, with multiple programs launching simultaneously [26][28] Question: What traffic has been seen since the FDA's guidance on AI-based systems? - There has been a significant increase in inquiries related to IND applications, with expectations for continued growth in the use of the Lens AI platform [30][37] Question: How far along is the divestment of the European facilities? - The divestment process is in the final stages, with a dedicated buyer and completion expected soon [38][40] Question: Is the Canadian facility able to handle the increased workload? - The Canadian facility is experiencing rapid growth and is equipped to manage the current workload, with ongoing expansions [41][44]