Core Insights - Integra LifeSciences Holdings Corporation (IART) reported adjusted earnings per share (EPS) of 83 cents for Q4 2025, exceeding the Zacks Consensus Estimate by 4.7%, but down 14.4% year over year [1][2] - Total revenues for Q4 2025 were $434.9 million, a decrease of 1.7% year over year, but slightly above the Zacks Consensus Estimate by 0.1% [3] - The company provided guidance for 2026, expecting revenues between $1.66 billion and $1.70 billion, and adjusted EPS between $2.30 and $2.40 [11][12] Financial Performance - GAAP loss per share was 2 cents in Q4 2025, compared to earnings of 25 cents in the same period last year [2] - Full-year 2025 adjusted EPS was $2.23, down 12.9% year over year [2] - Gross profit for Q4 2025 totaled $220.9 million, down 11.3% year over year, with a gross margin of 50.8%, a contraction of 549 basis points [7][9] Revenue Breakdown - Revenues in the Codman Specialty Surgical segment rose 2.7% year over year to $323.3 million, with Neurosurgery sales growing 1.4% [4] - Tissue Technologies' revenues fell 12.8% year over year to $111.6 million, with Wound Reconstruction sales declining 21.4% on an organic basis [5] - Private Label sales grew 20.1% due to improved partner orders [6] Operational Insights - The adjusted operating profit was $26.8 million, down 31.9% year over year, with an adjusted operating margin of 6.2%, a contraction of 272 basis points [9] - The company ended Q4 2025 with approximately $235 million in cash and cash equivalents, down from $246.4 million a year ago [10] - Cumulative net cash provided by operating activities was $50.4 million, compared to $129.4 million a year ago [10] Future Guidance - For Q1 2026, reported revenues are expected to be between $375 million and $390 million, with adjusted EPS anticipated in the range of 37 to 45 cents [12] - The Zacks Consensus Estimate for Q1 2026 revenues is pegged at $395 million, and for adjusted EPS at 43 cents [12]