Financial Data and Key Metrics Changes - The company is currently valued at approximately $15 million, which is significantly lower than the potential value of its esophageal cancer test, estimated to be worth hundreds of millions within a year [44] - The anticipated cash recovery from Crown Medical Collections is around $50 million, which is more than three times the company's current market cap [10][27] Business Line Data and Key Metrics Changes - Prophase Biopharma is focusing on the esophageal cancer test, which has recently been awarded a critical patent for eight key protein biomarkers associated with esophageal cancer [30][38] - Nebula Genomics has undergone significant restructuring, including shutting down its lab and changing its business model to focus on subscription renewals, which is expected to lead to profitability [48][49] Market Data and Key Metrics Changes - The esophageal cancer test market is substantial, with approximately 67 million endoscopies performed annually in the U.S., leading to a potential reimbursement of up to $28 billion from insurance companies [33][34] - The company is targeting a network of gastroenterologists to adopt its test, leveraging relationships with key opinion leaders and institutions like Mayo Clinic [64][103] Company Strategy and Development Direction - The company is pursuing a crypto treasury strategy, aiming to attract significant partners and raise capital through authorized shares, which is seen as crucial for future growth [67][78] - The management is focused on commercializing the esophageal cancer test and plans to publish studies in major journals to gain legitimacy and acceptance in the medical community [92][94] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in recovering funds from insurance companies through legal action, anticipating a court date within four to eight weeks [106] - The CEO highlighted the importance of shareholder support for the proposed increase in authorized shares to facilitate future capital raises and attract large partners [87][90] Other Important Information - The company has a history of success in the lab business, previously outperforming 95% of labs during the COVID testing phase, and aims to replicate that success with the new initiatives [15][28] - The management emphasized the need for clinical studies to support product claims, particularly for the Equivir product, which is currently awaiting final results [60] Q&A Session Summary Question: What are the next steps for BSmart? - The next steps include publishing a study in a major journal and engaging key opinion leaders to promote the test [92][93] Question: When will the esophageal cancer test hit the retail markets? - The test will be integrated into existing endoscopy procedures, requiring no additional steps from patients or doctors [99][100] Question: Can you provide an update on the timing for collecting from Crown? - The company expects to start collecting within four to eight weeks after the bankruptcy court proceedings begin [106] Question: What line of crypto investing opportunities are being considered? - The focus is primarily on Bitcoin, with aspirations to model the company's strategy after MicroStrategy [108]

Financial Data and Key Metrics Changes - The company reported a significant reduction in overhead costs, with a decrease in employee count from 96 to 25, leading to a more streamlined operation [20][21] - Shareholders' equity increased from approximately $7 million to over $15 million following the sale of a manufacturing facility, effectively doubling net assets [18][33] - The company anticipates substantial liquidity events in the second half of the year, potentially bringing in $50 million to $70 million [24][100] Business Line Data and Key Metrics Changes - Prophase Labs is focusing on three main business lines: B Smart esophageal cancer test, Nebula Genomics, and dietary supplements [7][12] - The B Smart esophageal cancer test is projected to have a market potential of $7 billion to $14 billion, with reimbursement expected to be between $1,000 to $2,000 per test [44][37] - DNA Complete is generating approximately $5 million in annual revenues, with potential to reach $10 million with increased marketing efforts [93] Market Data and Key Metrics Changes - The company is exploring strategic alternatives for Nebula Genomics, which has a significant genomic database of 16 petabytes, positioning it as a valuable asset in the market [56][58] - The esophageal cancer test is expected to be commercialized later this year, targeting a market of approximately 7 million endoscopies annually in the U.S. [38][80] Company Strategy and Development Direction - The company is focused on restructuring and cleaning up its balance sheet, with plans to avoid diversifying into new businesses and instead concentrate on existing operations [104] - Management is prioritizing debt financing over equity issuance to minimize shareholder dilution, aiming for a strong cash position once liquidity events occur [23][100] - The company is not pursuing vaccine development but is concentrating on its existing product lines and potential acquisitions [87][89] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the upcoming liquidity events and the potential for significant cash inflow, which is expected to improve the company's financial standing [100][102] - The CEO emphasized the importance of maintaining a lean operation and avoiding excessive spending on sales force development, opting for partnerships with existing sales networks instead [84][82] - Management is optimistic about the company's future, citing a strong alignment with shareholder interests and a commitment to improving operational efficiency [29][21] Other Important Information - The company is currently under NASDAQ compliance scrutiny but is confident in receiving a six-month extension based on meeting all other qualifications [30][91] - The CEO has deferred a significant portion of his salary until liquidity events occur, demonstrating commitment to the company's recovery [26] Q&A Session Summary Question: What is the realistic timeline for B Smart commercialization? - The CEO anticipates the first patient testing on a commercial basis later this year, but full commercialization will be a multi-year process [80] Question: What vaccines or illnesses are being worked on? - The company is not working on any vaccines and is focusing on the Acrovir product and dietary supplements [87] Question: What steps are being taken to meet NASDAQ compliance? - The CEO confirmed that an extension has been filed and expressed confidence in receiving it due to meeting all other criteria [90] Question: Has the DNA Complete division started generating revenues? - Yes, DNA Complete is generating around $5 million annually, with potential for growth through increased marketing [93] Question: Are we still looking at June/July for COVID testing payments? - The CEO indicated that payments could start coming in as early as June, depending on the progress with Crown Medical [96]

Financial Data and Key Metrics Changes - The company reported a significant increase in shareholders' equity, which roughly doubled from approximately $7 million to over $15 million following the sale of a manufacturing facility [16][34][92] - The company is currently operating at breakeven for its Nebula Genomics division, which is expected to generate substantial cash flow in the future [60][89] Business Line Data and Key Metrics Changes - The b smart esophageal cancer test is anticipated to have a market potential of $7 to $14 billion, with the company expecting to receive reimbursement of $1,000 to $2,000 per test [46][47] - DNA Complete is generating around $5 million in annual revenues, with potential to reach $10 million with increased marketing efforts [93] Market Data and Key Metrics Changes - The company is exploring strategic alternatives for Nebula Genomics and DNA Complete, aiming to clean up its capital structure and reduce pressure on the stock price [54] - The company has a large genomic dataset of 16 petabytes, which is one of the largest in the world, enhancing its market position [58] Company Strategy and Development Direction - The company plans to focus on debt financing rather than issuing shares, aiming to maintain shareholder value while preparing for upcoming liquidity events [22][102] - The management is committed to a methodical approach to commercialization of the b smart esophageal cancer test, leveraging existing sales networks rather than building a new sales force [84] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in collecting approximately $20 million in uncollected accounts receivable, with expectations that actual collections could exceed this amount [106] - The company anticipates significant cash inflows in the second half of the year, driven by collections and the potential sale of Nebula Genomics [99][104] Other Important Information - The company has deferred a significant portion of executive compensation until liquidity events occur, demonstrating alignment with shareholder interests [25] - The company is actively working on legal matters with Crown Medical to recover underpaid reimbursements from insurance companies, which could lead to additional cash inflows [70][73] Q&A Session Summary Question: What is a realistic timeline for the commercialization of BSmart? - The first patient testing is expected to occur later this year, but commercialization will likely be a multiyear process [81] Question: What vaccines or illnesses are being worked on? - The company is not currently working on any vaccines and is focusing on the b smart esophageal cancer test and dietary supplements [88] Question: What steps are being taken to meet Nasdaq compliance? - The company has filed for an extension and is confident it will receive it, as it meets all other qualifications [90][91] Question: Has the DNA Complete division started generating revenues? - DNA Complete is generating around $5 million annually, with potential for growth through increased marketing [93] Question: Are we still looking at June/July for COVID testing payments? - The company is optimistic about receiving payments in June, with significant capital expected to flow in the second half of the year [96][99] Question: Have you accessed the line of credit from the global private equity group? - A small amount of capital has been taken in, and the company is exploring additional debt financing options [102] Question: What milestone items should shareholders be aware of for the balance of 2025? - Key milestones include the development of the esophageal cancer test and the rollout of Equivira, with a focus on maintaining cash reserves [104]