Management Initiates Q4’25 Adjusted Revenue(3) Guidance of 31% to 43% Q-o-Q Growth Over 13 Million HYPE Tokens Staked to Hyperion’s Validator as of October 31, 2025 Ramping Business Lines Expected to Achieve Positive Operating Cash Flows in 2026 LAGUNA HILLS, Calif., Nov. 13, 2025 (GLOBE NEWSWIRE) -- Hyperion DeFi, Inc. (NASDAQ: HYPD) (“Hyperion DeFi” or the “Company”), the first U.S. publicly listed company building a long-term strategic treasury of Hyperliquid’s native token, HYPE, today reported results ...

Core Points - Hyperion DeFi, Inc. is the first U.S. publicly listed company focused on building a long-term strategic treasury of Hyperliquid's native token, HYPE [1][6] - The company will hold its earnings conference call for Q3 2025 on November 13, 2025, at 5:00 p.m. Eastern Time [1][3] - A press release detailing the earnings results will be issued prior to the call [2] Company Overview - Hyperion DeFi, Inc. provides investors with streamlined access to the Hyperliquid ecosystem, which is recognized as one of the fastest-growing and highest revenue-generating blockchains globally [6] - The company benefits shareholders through compounding exposure to HYPE, derived from its native staking yield and additional revenues from its on-chain utility [6] Hyperliquid Platform and HYPE Token - Hyperliquid is a next-generation layer one blockchain optimized for high-frequency, transparent trading, featuring fully on-chain perpetual futures and spot order books [4] - The HYPE token is the native token of Hyperliquid, with over 30 million HYPE autonomously purchased and sequestered by the blockchain as of October 2025 [5] - Staked HYPE offers users reduced trading fees and increased referral bonuses [5] Product Development - Hyperion DeFi is developing the Optejet User Filled Device (UFD), designed for various topical ophthalmic liquids, which may enhance treatment compliance and outcomes for patients with chronic front-of-the-eye diseases [7]

Core Insights - Hyperion DeFi has announced a strategic partnership with Felix to utilize 500,000 HYPE for launching a custom on-chain perpetual futures market, marking a significant advancement in decentralized finance [1][2][3] Group 1: Partnership and Product Development - The HYPE Asset Use Service (HAUS) agreement allows Hyperion DeFi to support Felix in managing a new market using the HIP-3 framework, which facilitates the creation of markets for non-crypto assets [2][3] - This partnership is expected to expand Hyperliquid's product offerings and user base while generating new revenue streams from staked HYPE assets [3][4] Group 2: Market Performance and Future Plans - Felix has achieved a total value locked (TVL) of over $1 billion as of September 2025, indicating strong market traction [4][11] - Felix plans to further integrate its DeFi infrastructure into the development of Felix Exchange, aiming to enhance liquidity access and stablecoin minting [4][5] Group 3: Hyperliquid Platform and HYPE Token - Hyperliquid is a next-generation blockchain designed for high-frequency trading, featuring on-chain perpetual futures and spot order books with rapid transaction times [6] - The HYPE token serves as the native currency of Hyperliquid, with over 30 million HYPE autonomously purchased and sequestered by the blockchain as of October 2025 [7][8]

Core Viewpoint - Hyperion DeFi, Inc. has appointed David Knox as Chief Financial Officer to enhance governance and accelerate its decentralized finance strategy, leveraging his extensive experience in capital markets and financial services [1][2][4]. Company Overview - Hyperion DeFi is the first U.S. publicly listed company focused on building a long-term strategic treasury of Hyperliquid's native token, HYPE [1][7]. - The company aims to provide shareholders with simplified access to the Hyperliquid ecosystem, which is recognized as one of the fastest-growing and highest revenue-generating blockchains globally [7]. Leadership and Expertise - David Knox previously held significant roles at PayPal, where he led the expansion of lending segments and managed financial planning and analysis [2][3]. - Knox's background includes advisory services in capital markets at Cantor Fitzgerald and roles in lending and capital markets at SoFi, Hudson Advisors, and the Royal Bank of Scotland [3]. Strategic Initiatives - The appointment of Knox is part of a broader initiative to position Hyperion DeFi at the forefront of the transition of institutional finance to decentralized platforms [4]. - Knox intends to leverage his industry connections to enhance Hyperion DeFi's offerings in fixed income and structured products [4]. Token and Platform Information - Hyperliquid is a layer one blockchain designed for high-frequency trading, featuring on-chain perpetual futures and spot order books with rapid transaction times [5]. - HYPE, the native token of Hyperliquid, has over 30 million tokens sequestered as of September 2025, making it the 16th-largest cryptocurrency by market capitalization [6]. Employee Incentives - In connection with Knox's appointment, the company granted him a restricted stock unit award of 100,000 shares, which will vest in two equal installments over the next year [4].

Core Insights - Hyperion DeFi, Inc. has increased its total holdings of HYPE tokens to 1,712,195 by acquiring an additional 176,422 tokens at an average price of $38.25 per token [1] - The company emphasizes the importance of HYPE in on-chain governance and plans to utilize its additional holdings for revenue-generating opportunities on HyperCore and HyperEVM [2] - Hyperliquid is a layer one blockchain designed for high-frequency trading, featuring on-chain perpetual futures and spot order books with 70 millisecond block times [3] - HYPE is the native token of Hyperliquid, providing utility through reduced trading fees and referral bonuses, with over 30 million HYPE sequestered by the blockchain as of September 2025 [4] - Hyperion DeFi is the first publicly listed U.S. company focused on building a strategic treasury of HYPE, aiming to provide shareholders with access to the growing Hyperliquid ecosystem [5] - The company is also developing the Optejet User Filled Device for ophthalmic liquids, which may enhance treatment compliance and outcomes for patients [6] Company Overview - Hyperion DeFi, Inc. is focused on creating a long-term treasury of HYPE tokens, benefiting shareholders through staking yields and additional revenues from on-chain utility [5] - The company is positioned within one of the fastest-growing and highest revenue-generating blockchain ecosystems [5] Product and Technology - Hyperliquid's blockchain supports permissionless decentralized financial applications through its HyperEVM, similar to Ethereum [3] - The Optejet User Filled Device is designed for ease of use and enhanced safety in administering topical ophthalmic treatments [6]

Core Insights - Hyperion DeFi, Inc. has announced its first HYPE Asset Use Service (HAUS) agreement with Credo Cayman, marking a significant step in its strategy to generate revenue through decentralized finance [1][2][3] Company Overview - Hyperion DeFi is the first U.S. publicly listed company focused on building a long-term strategic treasury of Hyperliquid's native token, HYPE [1][6] - The company aims to provide shareholders with simplified access to the Hyperliquid ecosystem, which is recognized as one of the fastest-growing and highest revenue-generating blockchains [6] HYPE Token and Hyperliquid Platform - HYPE is the native token of Hyperliquid, which offers reduced trading fees and increased referral bonuses for staked HYPE [5] - As of September 2025, over 30 million HYPE has been sequestered by the blockchain, making it the 16th-largest cryptocurrency by market capitalization [5] - Hyperliquid is a layer one blockchain optimized for high-frequency trading, featuring on-chain perpetual futures and spot order books with 70 millisecond block times [4] HAUS Agreement with Credo - The HAUS agreement involves the use of 100,000 staked HYPE by Credo, allowing the firm to significantly lower transaction fees on Hyperliquid [2] - The net fee savings from this agreement will be shared between Hyperion DeFi and Credo, creating a new revenue stream for both parties [2][3] - Credo's team consists of experienced traders and technologists who have transitioned from centralized venues to Hyperliquid for its lower fees and comparable trade settlement speeds [3] Future Developments - Hyperion DeFi is also developing the Optejet User Filled Device (UFD) for ophthalmic liquids, which aims to improve treatment compliance and outcomes for patients [7]

Core Insights - Kinetiq has launched iHYPE, an institutional-grade liquid staking product, with Hyperion DeFi, Inc. as its first institutional depositor, marking a significant milestone for institutional access to Hyperliquid's DeFi ecosystem [1][2]. Company Overview - Kinetiq is a leading liquid staking protocol on Hyperliquid, enabling seamless staking of HYPE while unlocking liquidity, yield, and DeFi composability, with over $1.3 billion in Total Value Locked (TVL) in its flagship product, kHYPE [8]. Product Features - iHYPE offers fully isolated, compliant staking pools built on a robust architecture, allowing professional allocators to access Hyperliquid-native staking yields without managing validator infrastructure or navigating fragmented DeFi tooling [2][3]. - Each deployment of iHYPE is customizable, KYB/KYC-enabled, and fully interoperable with institutional-grade integrations, facilitating seamless access to DeFi strategies, yield, and liquidity within compliance frameworks [3][4]. Institutional Engagement - Hyperion DeFi is the first U.S. publicly listed company to build a strategic treasury of Hyperliquid's native token, HYPE, providing shareholders with simplified access to the Hyperliquid ecosystem [6]. - The launch of iHYPE follows Kinetiq's previous announcement in June, transitioning the infrastructure from concept to execution and paving the way for broader institutional adoption [5]. Compliance and Integration - iHYPE is integrated with key partners, including trading firms, custodians, and validators, ensuring seamless onboarding and operational continuity for institutional participants [5]. - The product is designed to meet the demands of institutions, offering superior compliance features compared to standard solutions [7].

Core Insights - Hyperion DeFi, Inc. has established a cryptocurrency treasury reserve focused on the HYPE token and is the first publicly listed U.S. company to implement decentralized finance (DeFi) strategies on the Hyperliquid blockchain [1][3] - The company has accumulated over 1.5 million HYPE tokens and has formed a co-branded validator with Kinetiq, enhancing its on-chain engagement strategy [1][6] - The FDA registration for the Optejet User Filled Device (UFD) is on track for September 2025, indicating ongoing development in ophthalmic digital technologies [1][3] Financial Performance - For Q2 2025, the net loss attributable to common stockholders was $8.8 million, or $2.50 per share, an improvement from a net loss of $11.1 million, or $16.65 per share, in Q2 2024 [4][17] - Research and development expenses decreased by 85% to $0.7 million in Q2 2025, down from $4.6 million in Q2 2024, primarily due to a reduction in headcount following the termination of the CHAPERONE study [5] - General and administrative expenses increased by 104% to $7.7 million in Q2 2025, compared to $3.8 million in Q2 2024, driven by a one-time stock-based compensation grant and higher professional fees [7] Corporate Developments - The company closed a private placement financing of $50 million and successfully established its cryptocurrency treasury reserve [6] - A corporate rebranding was implemented, changing the name from Eyenovia, Inc. to Hyperion DeFi, Inc., reflecting its new focus on DeFi and blockchain technologies [6] - The company hosted a corporate update webinar to discuss its transformation and the potential of using blockchain-native assets like HYPE for scalable, yield-generating products [6] Asset and Cash Position - As of June 30, 2025, the company's unrestricted cash and cash equivalents were $7.5 million, a significant increase from $2.1 million at the end of 2024 [8] - Total assets as of June 30, 2025, amounted to $55.7 million, compared to $3.7 million at the end of 2024, indicating substantial growth in the company's asset base [15][16]

Company Overview - Hyperion DeFi, Inc. is the first U.S. publicly listed company focused on building a strategic treasury around the HYPE token, integrating decentralized finance with traditional corporate treasury strategies [4] - The company aims to provide shareholders with simplified access to the Hyperliquid ecosystem, which is recognized as one of the fastest-growing and highest revenue-generating blockchains globally [4] Financial Events - Hyperion DeFi will host its second quarter 2025 earnings call on August 13, 2025, at 4:30 p.m. ET to review financial and operating results [1] - Participants can join the call via a domestic number (1-877-407-9039) or an international number (1-201-689-8470) using the conference code 13754799 [2] Upcoming Meetings - The company reminds investors to vote ahead of its Annual General Meeting scheduled for August 18, 2025 [3] Product Development - Hyperion DeFi is developing the Optejet User Filled Device (UFD), designed for various topical ophthalmic liquids, which may enhance patient outcomes due to its ease of use and potential for better compliance compared to standard eye drops [5] - The company is exploring strategic options for the Optejet technology [5]

Core Viewpoint - Hyperion DeFi, Inc. has expanded its holdings of HYPE tokens to 1,535,772 by acquiring an additional 108,594 tokens at an average price of $36.14 per token, in preparation for deploying HYPE into Kinetiq's iHYPE pool, which is designed for institutional participants [2][3][4] Group 1: Company Developments - The acquisition of HYPE tokens is part of Hyperion DeFi's strategy to implement its HyperEVM DeFi strategy and to earn passive staking yields while enhancing capital efficiency [4][6] - Hyperion DeFi is the first public company to utilize Kinetiq's institutional-grade liquid staking solution, indicating a commitment to innovation in decentralized finance (DeFi) [4][5] - The company plans to participate in Kinetiq's kPoints incentive program, which positions it for future growth within the Kinetiq ecosystem [4][6] Group 2: Investor Engagement - Hyperion DeFi will host an investor webinar on July 29, 2025, to discuss its transformation into a publicly listed firm focused on building a strategic treasury around HYPE [7] - The webinar will include a live Q&A session, allowing investors to engage directly with the management team [7] Group 3: Hyperliquid Platform and HYPE Token - Hyperliquid is a layer one blockchain optimized for high-frequency trading, featuring on-chain perpetual futures and spot order books with rapid transaction times [8] - HYPE, the native token of Hyperliquid, provides utility through reduced trading fees and has autonomously sequestered over 25 million tokens as of June 2025, making it the 12th-largest cryptocurrency by market capitalization [9][10] Group 4: Kinetiq Collaboration - Kinetiq's iHYPE deployment is tailored for institutional clients and has quickly amassed over $600 million in Total Value Locked (TVL) within its first week, establishing it as a leading liquid staking protocol on Hyperliquid [15]